Bone marrow involvement in lymphomas with hemophagocytic syndrome at presentation: A clinicopathologic study of 11 patients in a Western institution

American Journal of Surgical Pathology

Volumn 25, Issue 7, 2001, Pages 865-874

  Allory, Yves ^a,b   Challine, Dominique ^a   Haioun, Corinne ^a   Copie Bergman, Christiane ^a   Delfau Larue, Marie H́ĺne ^a   Boucher, Eric ^e   Charlotte, Fŕd́ric ^c   Fabre, Monique ^d   Michel, Marc ^a   Gaulard, Philippe ^a  

^a HENRI MONDOR HOSPITAL   (France)

^b HÔPITAL TENON   (France)

^c PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^d BICÊTRE HOSPITAL   (France)

^e University of Paris Descartes   (France)

Author keywords

B cell lymphoma; Epstein Barr virus; Hemophagocytic syndrome; Human herpes virus 6; Human herpes virus 8; T NK cell lymphoma

Indexed keywords

CD20 ANTIGEN; CD3 ANTIGEN; VIRUS DNA;

ADOLESCENT; ADULT; AGED; ANTIBODY LABELING; ARTICLE; B CELL LYMPHOMA; BONE MARROW BIOPSY; BONE MARROW CANCER; CANCER DIAGNOSIS; CLINICAL ARTICLE; CLINICAL FEATURE; DISEASE ASSOCIATION; EPSTEIN BARR VIRUS; FEMALE; HEMATOPOIETIC CELL; HEMOPHAGOCYTIC SYNDROME; HISTOPATHOLOGY; HUMAN; HUMAN HERPESVIRUS 6; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; NONHODGKIN LYMPHOMA; OUTCOMES RESEARCH; T CELL LYMPHOMA;

ADOLESCENT; ADULT; AGED; BONE MARROW; FEMALE; HERPESVIRUS 4, HUMAN; HERPESVIRUS 6, HUMAN; HERPESVIRUS 8, HUMAN; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOMA, B-CELL; LYMPHOMA, T-CELL; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES;

EID: 0034956756     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-200107000-00004     Document Type: Article

References (62)

1. Macrophage activation syndromes
2. Gammaherpes viruses and 'hit-and-run' oncogenesis
3. Human herpes virus 6 (HHV-6)-positive Burkitt's lymphoma: Establishment of a novel cell line infected with HHV-6
4. Human herpes virus 8 infection in patients with POEMS syndrome-associated multicentric Castleman's disease
5. Absence of a directly causative role for human herpes virus 7 in human lymphoma and a review of human herpes virus 6 in human malignancy
6. Characteristic clinicopathologic features of Epstein-Barr virus-associated peripheral T-cell lymphoma
7. Primary non-Hodgkin's lymphoma of the nose and nasopharynx: Clinical features, tumor immunophenotype, and treatment outcome in 113 patients
8. Hepatosplenic T-cell lymphoma: A distinct clinicopathologic entity of cytotoxic gamma delta T-cell origin
9. T-cell lymphoma and the virus-associated hemophagocytic syndrome
10. Occult hepatosplenic T-gamma delta lymphoma: Value of genotypic analysis in the differential diagnosis
11. Peripheral T-cell lymphoma associated with hemophagocytic syndrome
12. Contemporary classification of histiocytic disorders. The WHO Committee on histiocytic/reticulum Cell Prolifs
13. Detection of high levels of human herpes virus-6 DNA in a lymphoma of a patient with Sjogren's syndrome
14. The relationship of Epstein-Barr virus to infection-related (sporadic) and familial hemophagocytic syndrome and secondary (lymphoma-related) hemophagocytosis: An in situ hybridization study
15. The oncogenic potential of herpes simplex viruses: Evidence for a 'hit-and-run' mechanism
16. Bone marrow histologic and immunohistochemical findings in peripheral T-cell lymphoma: A study of 38 cases
17. T-cell lymphoma involving subcutaneous tissue: A clinicopathologic entity commonly associated with hemophagocytic syndrome
18. Haemophagocytic syndrome in patients infected with the human immunodeficiency virus: Nine cases and a review
19. Hemophagocytic syndrome in five patients with Epstein-Barr virus negative B-cell lymphoma
20. Malignant lymphoma and erythrophagocytosis simulating malignant histiocytosis
21. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: A progress report
22. T gamma cells: A missing link between malignant histiocytosis and T cell leukemia-lymphoma?
23. Expression and localization of human herpes virus8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma, and multicentric Castleman's disease
24. Nasal T-cell lymphoma: A clinicopathologic entity associated with peculiar phenotype and with Epstein-Barr virus
25. Up-regulation of adhesion and MHC molecules on splenic monocyte/macrophages in adult haemophagocytic syndrome
26. Upregulation of tumor necrosis factor-alpha gene by Epstein-Barr virus and activation of macrophages in Epstein-Barr virus-infected T cells in the pathogenesis of hemophagocytic syndrome
27. Post transplant CD8+ gamma delta T-cell lymphoma associated with human herpes virus-6 infection
28. Haemophagocytosis in bone marrow aspirate: A review of the clinical course of 10 cases
29. Expression of human herpes virus-6 antigens in benign and malignant lymphoproliferative diseases
30. Epstein-Barr virus related hemophagocytic syndrome in a T-cell rich B-cell lymphoma
31. Kaposi's sarcoma-associated herpes virus infection prior to onset of Kaposi's sarcoma
32. Malignant histiocytosis-like B-cell lymphoma, a distinct pathologic variant of intravascular lymphomatosis: A report of five cases and review of the literature
33. An Asian variant of intravascular lymphomatosis: An updated review of malignant histiocytosis-like B-cell lymphoma
34. Nasal T-cell lymphoma associated with hemophagocytic syndrome
35. Hepato-splenic gamma delta T-cell lymphoma: A rare entity mimicking the hemophagocytic syndrome
36. Hemophagocytic syndrome in five patients with Epstein-Barr virus negative B-cell lymphoma
37. Clinicopathological study of severe chronic active Epstein-Barr virus infection that developed in association with lymphoproliferative disorder and/or hemophagocytic syndrome
38. Hepatosplenic gamma delta T-cell lymphoma: Relation to Epstein-Barr virus and activated cytotoxic molecules
39. The spectrum of reactive hemophagocytic syndrome in systemic lupus erythematosus
40. Detection of the human herpes virus-8-encoded cyclin protein in primary effusion lymphoma-derived cell lines
41. Hematophagic histiocytosis: A report of 23 new patients and a review of the literature
42. Virus-associated hemophagocytic syndrome: A benign histiocytic proliferation distinct from malignant histiocytosis
43. Bacteria-associated hemophagocytic syndrome
44. Kaposi's sarcoma-associated herpes virus (KSHV or HHV8) in primary effusion lymphoma: Ultrastructural demonstration of herpes virus in lymphoma cells
45. Etiological aspects of reactive hemophagocytoses: Retrospective study in 99 patients
46. B-cell lymphoma associated with haemophagocytic syndrome: A clinical, immunological and cytogenetic study
47. Lymphokine-induced phagocytosis in angiocentric immunoproliferative lesions (AIL) and malignant lymphoma arising in AIL
48. Perforin gene defects in familial hemophagocytic lymphohistiocytosis
49. Splenic involvement by aggressive malignant lymphomas of B-cell and T-cell types: A morphologic and immunophenotypic study
50. Epstein-Barr virus-containing T-cell lymphoma presents with hemophagocytic syndrome mimicking malignant histiocytosis
51. Human herpes virus 6 infection associated with hemophagocytic syndrome
52. Bone marrow findings in malignant histiocytosis and/or malignant lymphoma with concurrent hemophagocytic syndrome
53. MIP1alpha expression in tissues from patients with hemophagocytic syndrome
54. Acquisition of the human adeno-associated virus type-2 rep gene by human herpes virus type-6
55. Hemophagocytic syndromes: A series of 23 cases
56. Liver changes in reactive haemophagocytic syndrome
57. Malignant histiocytosis: A reassessment of cases previously reported in 1975 based on paraffin section immunophenotyping studies
58. Reactive hemophagocytic syndrome: A clinicopathologic study of 40 patients in an Oriental population
59. Large cell lymphoma with initial presentation in the bone marrow
60. Translocation (11;14) (q13;q32) in CD5-positive B-cell lymphoma associated with haemophagocytic syndrome
61. Clinicopathological spectrum of haemophagocytic syndrome in Epstein-Barr virus-associated peripheral T-cell lymphoma
62. Detection and quantification of cell-free Epstein-Barr virus by polymerase chain reaction and subsequent DNA enzyme immunoassay