메뉴 건너뛰기




Volumn 46, Issue 3, 2001, Pages 159-167

Dendritic cells (II): Role and therapeutic implications in cancer

Author keywords

Cytotoxic cells; Dendritic cells; Tumour associated antigens; Vaccination immuno therapy

Indexed keywords

CANCER VACCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PEPTIDE; TUMOR ANTIGEN;

EID: 0034955464     PISSN: 00358835     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (18)

References (106)
  • 5
    • 0028033444 scopus 로고
    • Follicular dendritic cell function and murine AIDS
    • (1994) Immunology , vol.81 , pp. 41-46
    • Masuda, A.1
  • 6
    • 0030984708 scopus 로고    scopus 로고
    • Langerhans' cells are depleted in chronic graft versus host disease
    • (1997) J Clin Pathol , vol.50 , pp. 305-309
    • Aractingi, S.1
  • 7
    • 0032788524 scopus 로고    scopus 로고
    • Kaposi's sarcoma in renal transplant recipients: Pathogenetic relation between the reduced density of Langerhans cells and cyclosporin-A therapy
    • (1999) J Nephrol , vol.12 , pp. 193-196
    • Bedani, P.L.1
  • 8
    • 0030820147 scopus 로고    scopus 로고
    • Epidermal Langerhans' cells in children with primary T-cell immune deficiencies
    • (1997) J Pathol , vol.183 , pp. 70-74
    • Emile, J.F.1
  • 9
    • 0032855131 scopus 로고    scopus 로고
    • Human immunodeficiency virus nef gene expression affects generation and function of human T cells, but not dendritic cells
    • (1999) Blood , vol.94 , pp. 2809-2818
    • Verhasselt, B.1
  • 10
    • 0033542437 scopus 로고    scopus 로고
    • The importance of defining the paraneoplastic neurologic disorders
    • (1999) N Engl J Med , vol.340 , pp. 1831-1833
    • Darnell, R.B.1
  • 11
    • 0029896951 scopus 로고    scopus 로고
    • Onconeural antigens and the paraneoplastic neurologic disorders: At the intersection of cancer, immunity, and the brain
    • (1996) Proc Natl Acad Sci , vol.93 , pp. 4529-4536
    • Darnell, R.B.1
  • 12
    • 0032425063 scopus 로고    scopus 로고
    • Tumour immunology: The glass is half full
    • (1998) Immunity , vol.9 , pp. 757-763
    • Sogn, G.A.1
  • 16
    • 0030858138 scopus 로고    scopus 로고
    • Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells
    • (see comments)
    • (1997) Nature , vol.388 , pp. 782-787
    • Cella, M.1
  • 17
    • 0030869567 scopus 로고    scopus 로고
    • Developmental regulation of MHC class II transport in mouse dendritic cells
    • (see comments)
    • (1997) Nature , vol.388 , pp. 787-792
    • Pierre, P.1
  • 18
    • 0028833639 scopus 로고
    • IL-10 inhibits tumor antigen presentation by epidermal antigen- presenting cells
    • (1995) J Immunol , vol.154 , pp. 1280-1286
    • Beissert, S.1
  • 19
    • 0031049941 scopus 로고    scopus 로고
    • Interleukin-10 prevents the generation of dendritic cells from human peripheral blood mononuclear cells cultured with interleukin-4 and granulocyte/macrophage-colony-stimulating factor
    • (1997) Eur J Immunol , vol.27 , pp. 756-762
    • Buelens, C.1
  • 20
    • 0026094306 scopus 로고
    • Interleukin-10 inhibits cytokine synthesis by human monocytes
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • de Waal Malefyt1
  • 21
    • 0029804814 scopus 로고    scopus 로고
    • Differential effects of interleukin-10 on the production of interleukin-12 and interleukin-8 by human dendritic cells generated from peripheral blood
    • (1996) Transplant Proc , vol.28 , pp. 3255-3256
    • Buelens, C.1
  • 22
    • 0029122603 scopus 로고
    • IL-10 inhibits the primary allogeneic T cell response to human peripheral blood dendritic cells
    • (1995) Adv Exp Med Biol , vol.378 , pp. 363-365
    • Buelens, C.1
  • 23
    • 0027320133 scopus 로고
    • Inhibition of Langerhans cell antigen-presenting function by IL-10. A role for IL-10 in induction of tolerance
    • (1993) J Immunol , vol.151 , pp. 2390-2398
    • Enk, A.H.1
  • 24
    • 0031974687 scopus 로고    scopus 로고
    • IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages
    • (1998) Eur J Immunol , vol.28 , pp. 359-369
    • Allavena, P.1
  • 25
    • 0033179404 scopus 로고    scopus 로고
    • IL-10 transgenic mice present a defect in T cell development reminiscent of SCID patients
    • (1999) J Immunol, , vol.163 , pp. 1420-1427
    • Rouleau, M.1
  • 26
    • 0033105695 scopus 로고    scopus 로고
    • Interleukin-10-treated human dendritic cells induce a melanoma-antigen-specific anergy in CD8(+) T cells resulting in a failure to lyse tumor cells
    • (1999) Blood , vol.93 , pp. 1634-1642
    • Steinbrink, K.1
  • 28
    • 0028646191 scopus 로고
    • Specificity and longevity of anti-tumor immune responses induced by B7-transfected tumors
    • (1994) Cancer Res , vol.54 , pp. 6477-6483
    • Townsend, S.E.1
  • 31
    • 0030707645 scopus 로고    scopus 로고
    • Quantitative contribution of CD4 and CD8 to T cell antigen receptor serial triggering
    • (1997) J Exp Med, , vol.186 , pp. 1775-1779
    • Viola, A.1
  • 32
    • 0029845747 scopus 로고    scopus 로고
    • T cell responses are governed by avidity and co-stimulatory thresholds
    • (1996) Eur J Immunol , vol.26 , pp. 2017-2022
    • Bachmann, M.F.1
  • 33
    • 0030786569 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells are defective in their antigen- presenting function and inducible B7 expression in rats
    • (1997) Int J Cancer , vol.72 , pp. 619-624
    • Chaux, P.1
  • 35
    • 0032211082 scopus 로고    scopus 로고
    • Defective function of Langerhans cells in tumor-bearing animals is the result of defective maturation from hemopoietic progenitors
    • (1998) J Immunol , vol.161 , pp. 4842-4851
    • Ishida, T.1
  • 36
    • 0004711556 scopus 로고
    • Mouse tumour-associated macrophages do not generate pro coagulation activity in response to different stimuli
    • (1993) Int J Cancer , vol.36 , pp. 108-114
    • Erroi, A.1
  • 37
    • 0027506726 scopus 로고
    • Depressed monocyte polarisation and clustering of dendritic cells in patients with head and neck cancer: In vitro restoration of this immunosuppression by thymic hormones
    • (1993) Cancer Immunol Immunother , vol.36 , pp. 108-114
    • Tas, M.P.1
  • 40
    • 0028965830 scopus 로고
    • Activated macrophages induces structural abnormalities of the T cell receptor-CD3 complex
    • (1995) J Exp Med , vol.181 , pp. 1881-1886
    • Aoe, T.1    Saito, T.2
  • 42
    • 0028179056 scopus 로고
    • Role of bone marrow-derived cells in presenting MHC class I-restricted tumour antigen
    • (1994) Science , vol.264 , pp. 961-965
    • Huang, A.Y.1
  • 43
    • 0027284742 scopus 로고
    • Characterisation of antigen-presenting cells that present exogenous antigens in association with class I MHC molecules
    • (1993) J Immunol , vol.150 , pp. 438-446
    • Rock, K.L.1
  • 44
    • 0028845887 scopus 로고
    • Dendritic antigen-presenting cells from the peripheral blood of renal- cell-carcinoma patients
    • (1995) Int J Cancer , vol.63 , pp. 627-632
    • Radmayr, C.1
  • 45
    • 0034125451 scopus 로고    scopus 로고
    • Clinical significance of defective dendritic cell differentiation in cancer
    • (In Process Citation)
    • (2000) Clin Cancer Res , vol.6 , pp. 1755-1766
    • Almand, B.1
  • 46
    • 0031588347 scopus 로고    scopus 로고
    • Increased presence of CD34+ cells in the peripheral blood of head and neck cancer patients and their differentiation into dendritic cells
    • (1997) Int J Cancer , vol.73 , pp. 663-669
    • Garrity, T.1
  • 47
    • 0032964262 scopus 로고    scopus 로고
    • Dendritic cell differentiation pathways of CD34+ cells from the peripheral blood of head and neck cancer patients
    • (1999) J Leukoc Biol , vol.65 , pp. 623-628
    • Lathers, D.M.1
  • 49
    • 0033571785 scopus 로고    scopus 로고
    • In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas
    • (1999) J Exp Med , vol.190 , pp. 1417-1426
    • Bell, D.1
  • 50
    • 0033060409 scopus 로고    scopus 로고
    • Tumor-infiltrating dendritic cells in adenocarcinomas of the breast: A study of 143 neoplasms with a correlation to usual prognostic factors and to clinical outcome
    • (1999) Int J Cancer , vol.84 , pp. 309-314
    • Lespagnard, L.1
  • 52
    • 0030724702 scopus 로고    scopus 로고
    • Dendritic cells as mediators of tumor-induced tolerance in metastatic melanoma
    • (1997) Int J Cancer , vol.73 , pp. 309-316
    • Enk, A.H.1
  • 53
    • 0032945915 scopus 로고    scopus 로고
    • Direct and indirect T cell priming by dendritic cell vaccines
    • (1999) Eur J Immunol , vol.29 , pp. 225-234
    • Cayeux, S.1
  • 54
    • 0032807075 scopus 로고    scopus 로고
    • Dendritic cells with immature phenotype and defective function in the peripheral blood from patients with hepatocellular carcinoma
    • (1999) J Hepatol , vol.31 , pp. 323-331
    • Ninomiya, T.1
  • 55
    • 0030028770 scopus 로고    scopus 로고
    • Murine dendritic cells loaded in vitro with soluble protein prime cytotoxic T lymphocytes against tumor antigen in vivo
    • (see comments)
    • (1996) J Exp Med , vol.183 , pp. 317-322
    • Paglia, P.1
  • 56
    • 0030058647 scopus 로고    scopus 로고
    • Therapy of murine tumors with tumor 7 peptide-pulsed dendritic cells: Dependence on T cells, B7 co-stimulation, and T helper cell 1-associated cytokines
    • (see comments)
    • (1996) J Exp Med , vol.183 , pp. 87-97
    • Zitvogel, L.1
  • 57
    • 0028347936 scopus 로고
    • Murine dendritic cells pulsed in vitro with tumor antigen induce tumor resistance in vivo
    • (1994) Eur J Immunol , vol.24 , pp. 605-610
    • Flamand, V.1
  • 58
    • 0028793675 scopus 로고
    • Bone marrow-derived dendritic cells pulsed with synthetic tumour peptides elicit protective and therapeutic anti-tumour immunity
    • (1995) Nat Med , vol.1 , pp. 1297-1302
    • Mayordomo, J.I.1
  • 59
    • 0030896205 scopus 로고    scopus 로고
    • Bone marrow-derived dendritic cells serve as potent adjuvants for peptide-based anti-tumor vaccines
    • (1997) Stem Cells , vol.15 , pp. 94-103
    • Mayordomo, J.I.1
  • 61
    • 0030904482 scopus 로고    scopus 로고
    • Induction of antitumor activity by immunisation with fusions of dendritic and carcinoma cells
    • (1997) Nat Med , vol.3 , pp. 558-561
    • Gong, J.1
  • 62
    • 0030781054 scopus 로고    scopus 로고
    • Dendritic cells retrovirally transduced with a model antigen gene are therapeutically effective against established pulmonary metastases
    • (1997) J Exp Med , vol.186 , pp. 1213-1221
    • Specht, J.M.1
  • 63
    • 0029005321 scopus 로고
    • Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes
    • (1995) J Exp Med , vol.182 , pp. 255-260
    • Porgador, A.1    Gilboa, E.2
  • 64
    • 0030856119 scopus 로고    scopus 로고
    • Dendritic cells genetically modified with an adenovirus vector encoding the cDNA for a model antigen induce protective and therapeutic anti-tumor immunity
    • (1997) J Exp Med , vol.186 , pp. 1247-1256
    • Song, W.1
  • 65
    • 0029839058 scopus 로고    scopus 로고
    • Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo
    • (1996) J Exp Med , vol.184 , pp. 465-472
    • Boczkowski, D.1
  • 66
    • 0030026776 scopus 로고    scopus 로고
    • Vaccination of patients with B-cell lymphoma using autologous antigen- pulsed dendritic cells
    • (1996) Nat Med , vol.2 , pp. 52-58
    • Hsu, F.J.1
  • 67
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
    • (see comments)
    • (1998) Nat Med , vol.4 , pp. 328-332
    • Nestle, F.O.1
  • 68
    • 0032892718 scopus 로고    scopus 로고
    • Infusion of dendritic cells pulsed with HLA-A2-specific prostate-specific membrane antigen peptides: A phase II prostate cancer vaccine trial involving patients with hormone-refractory metastatic disease
    • (1999) Prostate , vol.38 , pp. 73-78
    • Murphy, G.P.1
  • 69
    • 0032754286 scopus 로고    scopus 로고
    • Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells
    • (1999) J Clin Invest , vol.104 , pp. 173-180
    • Dhodapkar, M.V.1
  • 71
    • 0033516548 scopus 로고    scopus 로고
    • Induction of carcinoembryonic antigen (CEA)-specific cytotoxic T- lymphocyte responses in vitro using autologous dendritic cells loaded with CEA peptide or CEA RNA in patients with metastatic malignancies expressing CEA
    • (1999) Int J Cancer , vol.82 , pp. 121-124
    • Nair, S.K.1
  • 72
    • 0028285230 scopus 로고
    • Proliferating dendritic cell progenitors in human blood
    • (1994) J Exp Med , vol.180 , pp. 83-93
    • Romani, N.1
  • 73
    • 0032080819 scopus 로고    scopus 로고
    • Dendritic cells as the terminal stage of monocyte differentiation
    • (1998) J Immunol , vol.160 , pp. 4587-4595
    • Palucka, K.A.1
  • 74
    • 0026446156 scopus 로고
    • GM-CSF and TNF-alpha cooperate in the generation of dendritic Langerhans cells
    • (1992) Nature , vol.360 , pp. 258-261
    • Caux, C.1
  • 75
    • 0032529213 scopus 로고    scopus 로고
    • Type I IFNs enhance the terminal differentiation of dendritic cells
    • (1998) J Immunol , vol.161 , pp. 1947-1953
    • Luft, T.1
  • 76
    • 0032960197 scopus 로고    scopus 로고
    • Generation of tumor immunity by bone marrow-derived dendritic cells correlates with dendritic cell maturation stage
    • (1999) J Immunol , vol.162 , pp. 168-175
    • Labeur, M.S.1
  • 77
    • 0025259714 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor promotes differentiation and survival of human peripheral blood dendritic cells in vitro
    • (1990) J Clin Invest , vol.85 , pp. 955-961
    • Markowicz, S.1    Engleman, E.G.2
  • 78
    • 0020031143 scopus 로고
    • Human dendritic cells. Enrichment and characterisation from peripheral blood
    • (1982) J Exp Med , vol.155 , pp. 1172-1187
    • Van Voorhis, W.C.1
  • 79
    • 0023870862 scopus 로고
    • Accessory cell requirements for the mixed-leukocyte reaction and polyclonal mitogens, as studied with a new technique for enriching blood dendritic cells
    • (1988) Cell Immunol , vol.111 , pp. 167-182
    • Young, J.W.1    Steinman, R.M.2
  • 81
    • 0022615116 scopus 로고
    • Non-adherent, low-density cells from human peripheral blood contain dendritic cells and monocytes, both with veiled morphology
    • (1986) Immunology , vol.57 , pp. 595-603
    • Knight, S.C.1
  • 82
    • 0003121739 scopus 로고    scopus 로고
    • Immunisation with dendritic cells pulsed with xenogeneic prostatic acid phosphatase administered via different routes induces cellular immune responses in prostate cancer patients
    • (1999) Proc Am Assoc Cancer Res. , vol.40 , pp. 85-96
    • Fong, L.1
  • 83
    • 0035869523 scopus 로고    scopus 로고
    • Dendritic cells injected via different routes induce immunity in cancer patients
    • (2001) J Immunol , vol.166 , pp. 4254-4259
    • Fong, L.1
  • 84
    • 0029893672 scopus 로고    scopus 로고
    • Dendritic cells in anti-tumor immune responses. II. Dendritic cells growth from bone marrow precursors, but not mature DC from tumor-bearing mice, are effective antigen carriers in the therapy of established tumors
    • (1996) Cell Immunol , vol.170 , pp. 111-119
    • Gabrilovich, D.I.1
  • 85
    • 0029911677 scopus 로고    scopus 로고
    • Therapy of murine tumors with p53 wild-type and mutant sequence peptide-based vaccines
    • (1996) J Exp Med , vol.183 , pp. 1357-1365
    • Mayordomo, J.I.1
  • 86
    • 0026734842 scopus 로고
    • Identification of target antigens for the human cytotoxic T cell response to Epstein-Barr virus (EBV): Implications for the immune control of EBV-positive malignancies
    • (1992) J Exp Med , vol.176 , pp. 157-168
    • Murray, R.J.1
  • 87
    • 0030848375 scopus 로고    scopus 로고
    • Genetic immunisation for the melanoma antigen MART-1/Melan-A using recombinant adenovirus-transduced murine dendritic cells
    • (1997) Cancer Res , vol.57 , pp. 2865-2869
    • Ribas, A.1
  • 88
    • 0033950494 scopus 로고    scopus 로고
    • Dendritic cells loaded with MART-1 peptide or infected with adenoviral construct are functionally equivalent in the induction of tumor-specific cytotoxic T lymphocyte responses in patients with melanoma
    • (2000) J Immunother , vol.23 , pp. 168-176
    • Philip, R.1
  • 89
    • 0033949986 scopus 로고    scopus 로고
    • Generation of T-cell immunity to a murine melanoma using MART-1- engineered dendritic cells
    • (2000) J Immunother , vol.23 , pp. 59-66
    • Ribas, A.1
  • 90
    • 0031839320 scopus 로고    scopus 로고
    • The role of tumor necrosis factor alpha in modulating the quantity of peripheral blood-derived, cytokine-driven human dendritic cells and its role in enhancing the quality of dendritic cell function in presenting CD4+ T cells in vitro
    • (1998) Blood , vol.91 , pp. 4652-4661
    • Chen, B.1
  • 91
    • 0032527908 scopus 로고    scopus 로고
    • Optimisation of the sequence of antigen loading and CD40-ligand-induced maturation of dendritic cells
    • (1998) Cancer Res , vol.58 , pp. 2965-2968
    • Morse, M.A.1
  • 93
    • 0033514937 scopus 로고    scopus 로고
    • Systemic administration of interleukin 2 enhances the therapeutic efficacy of dendritic cell-based tumor vaccines
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2268-2273
    • Shimizu, K.1
  • 94
    • 0035862333 scopus 로고    scopus 로고
    • Antigen-specific Inhibition of Effector T Cell Function in Humans after Injection of Immature Dendritic Cells
    • (2001) J Exp Med , vol.193 , pp. 233-238
    • Dhodapkar, M.V.1
  • 95
    • 0034023485 scopus 로고    scopus 로고
    • Mature dendritic cells boost functionally superior CD8(+) T-cell in humans without foreign helper epitopes
    • (2000) J Clin Invest , vol.105
    • Dhodapkar, M.V.1
  • 96
    • 0031941423 scopus 로고    scopus 로고
    • Vaccination of melanoma patients with peptide- or tumor lysate-pulsed dendritic cells
    • (1998) Nat Med , vol.4 , pp. 328-332
    • Nestle, F.O.1
  • 97
  • 98
    • 0033405438 scopus 로고    scopus 로고
    • Vaccination with mage-3A1 peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma
    • (1999) J Exp Med , vol.190 , pp. 1669-1678
    • Thurner, B.1
  • 99
    • 0033120389 scopus 로고    scopus 로고
    • Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma - A feasibility study
    • (1999) Blood , vol.93 , pp. 2411-2419
    • Reichardt, V.L.1
  • 100
    • 0034652619 scopus 로고    scopus 로고
    • Dendritic cell-based immunotherapy of prostate cancer: Immune monitoring of a phase II clinical trial
    • (2000) Cancer Res , vol.60 , pp. 829-833
    • Lodge, P.A.1
  • 101
    • 0031895770 scopus 로고    scopus 로고
    • Report of immune monitoring of prostate cancer patients undergoing T-cell therapy using dendritic cells pulsed with HLA-A2-specific peptides from prostate-specific membrane antigen (PSMA)
    • (1998) Prostate , vol.35 , pp. 144-151
    • Salgaller, M.L.1
  • 102
    • 0034554863 scopus 로고    scopus 로고
    • Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells
    • (2000) J Clin Oncol , vol.18 , pp. 3894-3903
    • Small, E.J.1
  • 103
    • 0343882022 scopus 로고    scopus 로고
    • Mature dendritic cells induce T-helper type-1-dominant immune responses in patients with metastatic renal cell carcinoma
    • (2000) Urol Int , vol.63 , pp. 151-159
    • Rieser, C.1
  • 104
    • 0344678389 scopus 로고    scopus 로고
    • Cellular and humoral immune responses in patients with metastatic renal cell carcinoma after vaccination with antigen pulsed dendritic cells
    • (1999) J Urol , vol.161 , pp. 777-782
    • Holtl, L.1
  • 105
    • 0034100896 scopus 로고    scopus 로고
    • Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids
    • (2000) Nat Med , vol.6 , pp. 332-336
    • Kugler, A.1
  • 106
    • 0034331218 scopus 로고    scopus 로고
    • Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells
    • (2000) Blood , vol.96 , pp. 3102-3108
    • Brossart, P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.