Formulation of high tensile strength rapidly disintegrating tablets: Evaluation of the effect of some binder properties

S.T.P. Pharma Sciences

Volumn 11, Issue 3, 2001, Pages 211-220

  Mattsson, S ^a   Bredenberg, S ^a   Nystrom C ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Ac Di Sol; Binder; Compaction; Deformability; Disintegration; Fragmentation; Porosity; Superdisintegrant; Tablet strength

Indexed keywords

DISINTEGRATING AGENT; LACTOSE; MACROGOL;

ARTICLE; POROSITY; SOLUBILITY; TABLET DISINTEGRATION TIME; TABLET FORMULATION; TABLET SURFACE; TENSILE STRENGTH;

EID: 0034955006     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

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14. Contact angles and wetting of pharmaceutical powders
15. Comparison of solid-state NMR and isothermal microcalorimetry in the assessment of the amorphous component of lactose
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22. Heckel plots as indicators of elastic properties of pharmaceuticals
23. Evaluation of the effect of addition of polyethylene glycols of differing molecular weight on the mechanical strength of sodium chloride and sodium bicarbonate
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28. Substance behaviour in direct compression
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31. Tabletting properties of microcrystalline cellulose
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33. Effect of microcrystalline cellulose and cross-linked sodium carboxymethyl cellulose on the properties of tablets with methyl cellulose as a binder
34. Dissolution properties of direct compression tablets containing an agglomerate cellulose powder
35. Effect of formulation solubility and hygroscopicity on disintegrant efficiency in tablets prepared by wet granulation, in terms of dissolution