The carboxyl terminus of the human cytomegalovirus UL37 immediate-early glycoprotein is conserved in primary strains and is important for transactivation

Journal of General Virology

Volumn 82, Issue 7, 2001, Pages 1569-1579

  Hayajneh, W A ^a   Contopoulos Ioannidis, D G ^a   Lesperance, M M ^a   Venegas, A M ^a   Colberg Poley, A M ^a  

^a Children's Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLYCOPROTEIN; IMMEDIATE EARLY PROTEIN; MUTANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOSOL; ENDOPLASMIC RETICULUM; EXON; GENE SEQUENCE; GENETIC CONSERVATION; GENETIC VARIABILITY; GLYCOSYLATION; HUMAN CYTOMEGALOVIRUS; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN TRANSPORT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; TRANSACTIVATION; VIROGENESIS; VIRUS CULTURE; VIRUS ENVELOPE; VIRUS GENE; VIRUS PATHOGENESIS;

CYTOMEGALOVIRUS; DNA VIRUSES; HUMAN HERPESVIRUS 5; MAIZE CHLOROTIC MOTTLE VIRUS;

EID: 0034953928     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-82-7-1569     Document Type: Article

References (36)

1. The human cytomegalovirus UL37 immediate-early regulatory protein is an integral membrane N-glycoprotein which traffics through the endoplasmic reticulum and Golgi apparatus
2. DNA sequence and expression of the B95-8 Epstein-Barr virus genome
3. Human cytomegalovirus US3 gene expression is regulated by a complex network of positive and negative regulators
4. Cloning of the human cytomegalovirus (HCMV) genome as an infectious bacterial artificial chromosome in Escherichia coli: A new approach for construction of HCMV mutants
5. Cytomegalovirus
6. Human cytomegalovirus clinical isolates carry at least 19 genes not found in laboratory strains
7. Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169
8. Effect of interstrain variation on diagnostic DNA amplification of the cytomegalovirus major immediate-early gene region
9. Analysis of interstrain variation in cytomegalovirus glycoprotein B sequences encoding neutralization-related epitopes
10. Functional roles of immediate early proteins encoded by the human cytomegalovirus UL36-38, UL115-119, TRS1/IRS1 and US3 loci
11. The HCMV US3 and UL36-38 immediate early proteins regulate gene expression
12. The acidic domain of pUL37×1 and gpUL37 plays a key role in transactivation of HCMV DNA replication gene promoter constructions
13. Human cytomegalovirus UL37 immediate-early regulatory proteins traffic through the secretory apparatus and to mitochondria
14. Analysis of cytomegalovirus gene expression by transfection
15. The complete DNA sequence of varicella-zoster virus
16. A sensitive method for detection of β-galactosidase in transfected mammalian cells
17. A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to bcl-2
18. The DNA sequence of human herpesvirus 6: Structure, coding content, and genome evolution
19. Sequence and antiapoptotic functional domains of the human cytomegalovirus UL37 exon 1 immediate early protein are conserved in multiple primary strains
20. An immediate early gene of human cytomegalovirus encodes a potential membrane glycoprotein
21. Murine cytomegalovirus containing a mutation at open reading frame M37 is severely attenuated in growth and virulence in vivo
22. PCR detection of human cytomegalovirus DNA in clinical specimens using novel UL37 exon 3 and US3 primers
23. Human cytomegalovirus UL144 open reading frame: Sequence hypervariability in low-passage clinical strains
24. The genomes of the human herpesviruses: Contents, relationships, and evolution
25. Intragenic variability of human cytomegalovirus glycoprotein B in clinical strains
26. Determination and analysis of the complete nucleotide sequence of human herpesvirus 7
27. Nucleotide sequence analysis of a 38.5-kilobase-pair region of the genome of human herpesvirus 6 encoding human cytomegalovirus immediate-early gene homologs and transactivating functions
28. Potent antiviral activity of an antisense oligonucleotide complementary to the intron-exon boundary of human cytomegalovirus genes UL36 and UL37
29. Analysis of the complete DNA sequence of murine cytomegalovirus
30. Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)
31. Expression of human cytomegalovirus UL36 and UL37 genes is required for viral DNA replication
32. The human cytomegalovirus US3 immediate early protein lacking the putative transmembrane domain regulates gene expression
33. Complete DNA sequence of the rat cytomegalovirus genome
34. Transcription of the immediate early genes of human cytomegalovirus AD169
35. The acidic domain of the human cytomegalovirus UL37 immediate early protein is dispensable for its transactivating activity and localization but is not for its synergism
36. Sequence variation within three important cytomegalovirus gene regions in isolates from four different patient populations