메뉴 건너뛰기




Volumn 261, Issue 2, 1999, Pages 155-164

Human cytomegalovirus US3 gene expression is regulated by a complex network of positive and negative regulators

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; IMMEDIATE EARLY PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

EID: 0033199998     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.9881     Document Type: Article
Times cited : (17)

References (43)
  • 1
  • 2
    • 0029148434 scopus 로고
    • Regulation of human cytomegalovirus US3 gene transcription by a cis-repressive sequence
    • Biegalke B. J. Regulation of human cytomegalovirus US3 gene transcription by a cis-repressive sequence. J. Virol. 69:1995;5362-5367.
    • (1995) J. Virol. , vol.69 , pp. 5362-5367
    • Biegalke, B.J.1
  • 3
    • 0030817025 scopus 로고    scopus 로고
    • IE2 protein is insufficient for transcriptional repression of the human cytomegalovirus US3 promoter
    • Biegalke B. J. IE2 protein is insufficient for transcriptional repression of the human cytomegalovirus US3 promoter. J. Virol. 71:1997;8056-8060.
    • (1997) J. Virol. , vol.71 , pp. 8056-8060
    • Biegalke, B.J.1
  • 4
    • 0031747494 scopus 로고    scopus 로고
    • Characterization of the transcriptional repressive element of the human cytomegalovirus immediate-early US3 gene
    • Biegalke B. J. Characterization of the transcriptional repressive element of the human cytomegalovirus immediate-early US3 gene. J. Virol. 72:1998;5457-5463.
    • (1998) J. Virol. , vol.72 , pp. 5457-5463
    • Biegalke, B.J.1
  • 5
    • 0025360010 scopus 로고
    • Translational inhibition by cytomegalovirus transcript leaders
    • Biegalke B. J., Geballe A. P. Translational inhibition by cytomegalovirus transcript leaders. Virology. 177:1990;657-667.
    • (1990) Virology , vol.177 , pp. 657-667
    • Biegalke, B.J.1    Geballe, A.P.2
  • 6
    • 0025915332 scopus 로고
    • Sequence requirements for activation of the HIV-1 LTR by human cytomegalovirus
    • Biegalke B. J., Geballe A. P. Sequence requirements for activation of the HIV-1 LTR by human cytomegalovirus. Virology. 183:1991;381-385.
    • (1991) Virology , vol.183 , pp. 381-385
    • Biegalke, B.J.1    Geballe, A.P.2
  • 7
    • 0004250845 scopus 로고    scopus 로고
    • B. N. Fields, D. M. Knipe, & P. M. Howley. Philadelphia: Lippincott-Raven
    • Britt W. J., Alford C. A. Fields B. N., Knipe D. M., Howley P. M. Fields Virology. 1996;2493-2524 Lippincott-Raven, Philadelphia.
    • (1996) Fields Virology , pp. 2493-2524
    • Britt, W.J.1    Alford, C.A.2
  • 8
    • 0029897324 scopus 로고    scopus 로고
    • Two distinct upstream regulatory domains containing multicopy cellular transcription factor binding sites provide basal repression and inducible enhancer characteristics to the immediate-early IES (US3) promoter from human cytomegalovirus
    • Chan Y. J., Tseng W. P., Hayward G. S. Two distinct upstream regulatory domains containing multicopy cellular transcription factor binding sites provide basal repression and inducible enhancer characteristics to the immediate-early IES (US3) promoter from human cytomegalovirus. J. Virol. 70:1996;5312-5328.
    • (1996) J. Virol. , vol.70 , pp. 5312-5328
    • Chan, Y.J.1    Tseng, W.P.2    Hayward, G.S.3
  • 10
    • 0024543825 scopus 로고
    • Human cytomegalovirus ie1 transactivates the a promoter-enhancer via an 18-base-pair repeat element
    • Cherrington J. M., Mocarski E. S. Human cytomegalovirus ie1 transactivates the a promoter-enhancer via an 18-base-pair repeat element. J.Virol. 63:1989;1435-1440.
    • (1989) J.Virol. , vol.63 , pp. 1435-1440
    • Cherrington, J.M.1    Mocarski, E.S.2
  • 11
    • 0030426898 scopus 로고    scopus 로고
    • Functional roles of immediate early proteins encoded by the human cytomegalovirus UL36-38, UL115-119, TRS1/IRS1 and US3 loci
    • Colberg-Poley A. M. Functional roles of immediate early proteins encoded by the human cytomegalovirus UL36-38, UL115-119, TRS1/IRS1 and US3 loci. Intervirology. 39:1996;350-360.
    • (1996) Intervirology , vol.39 , pp. 350-360
    • Colberg-Poley, A.M.1
  • 12
  • 13
    • 17444435232 scopus 로고    scopus 로고
    • The acidic domain of pUL37x1 and gpUL37 plays a key role in transactivation of HCMV DNA replication gene promoter constructions
    • Colberg-Poley A. M., Huang L., Soltero V. E., Iskendrian A. C., Schumacher R. F., Anders D. G. The acidic domain of pUL37x1 and gpUL37 plays a key role in transactivation of HCMV DNA replication gene promoter constructions. Virology. 246:1998;400-408.
    • (1998) Virology , vol.246 , pp. 400-408
    • Colberg-Poley, A.M.1    Huang, L.2    Soltero, V.E.3    Iskendrian, A.C.4    Schumacher, R.F.5    Anders, D.G.6
  • 14
    • 0020314298 scopus 로고
    • Cloning of the complete huma cytomegalovirus genome in cosmids
    • Fleckenstein B., Müller I., Collins J. Cloning of the complete huma cytomegalovirus genome in cosmids. Gene. 18:1982;46.
    • (1982) Gene , vol.18 , pp. 46
    • Fleckenstein, B.1    Müller, I.2    Collins, J.3
  • 15
    • 0030760254 scopus 로고    scopus 로고
    • The UL84 protein of human cytomegalovirus acts as a transdominant inhibitor of immediate-early-mediated transactivation that is able to prevent viral replication
    • Gebert S., Schmolke S., Sorg G., Flöss S., Plachter B., Stamminger T. The UL84 protein of human cytomegalovirus acts as a transdominant inhibitor of immediate-early-mediated transactivation that is able to prevent viral replication. J. Virol. 71:1997;7048-7060.
    • (1997) J. Virol. , vol.71 , pp. 7048-7060
    • Gebert, S.1    Schmolke, S.2    Sorg, G.3    Flöss, S.4    Plachter, B.5    Stamminger, T.6
  • 16
    • 0025281335 scopus 로고
    • Human cytomegalovirus immediate-early two protein region involved in negative regulation of the major immediate-early promoter
    • Hermiston T. W., Malone C. L., Stinski M. F. Human cytomegalovirus immediate-early two protein region involved in negative regulation of the major immediate-early promoter. J. Virol. 64:1990;3532-3536.
    • (1990) J. Virol. , vol.64 , pp. 3532-3536
    • Hermiston, T.W.1    Malone, C.L.2    Stinski, M.F.3
  • 17
    • 0023218423 scopus 로고
    • Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoter
    • Hermiston T. W., Malone C. L., Witte P. R., Stinski M. F. Identification and characterization of the human cytomegalovirus immediate-early region 2 gene that stimulates gene expression from an inducible promoter. J. Virol. 61:1987;3214-3221.
    • (1987) J. Virol. , vol.61 , pp. 3214-3221
    • Hermiston, T.W.1    Malone, C.L.2    Witte, P.R.3    Stinski, M.F.4
  • 18
    • 0029655255 scopus 로고    scopus 로고
    • Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes
    • Iskenderian A. C., Huang L., Reilly M. J., Stenberg R. M., Anders D. G. Four of eleven loci required for transient complementation of human cytomegalovirus DNA replication cooperate to activate expression of replication genes. J. Virol. 70:1996;383-392.
    • (1996) J. Virol. , vol.70 , pp. 383-392
    • Iskenderian, A.C.1    Huang, L.2    Reilly, M.J.3    Stenberg, R.M.4    Anders, D.G.5
  • 19
    • 0026563860 scopus 로고
    • A cluster of dispensable genes within the human cytomegalovirus genome short component: IRS1,US1 through US5, and the US6 family
    • Jones T. R., Muzithras V. P. A cluster of dispensable genes within the human cytomegalovirus genome short component: IRS1,US1 through US5, and the US6 family. J. Virol. 66:1992;2541.
    • (1992) J. Virol. , vol.66 , pp. 2541
    • Jones, T.R.1    Muzithras, V.P.2
  • 20
    • 0029969098 scopus 로고    scopus 로고
    • Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains
    • Jones T. R., Wiertz E. J. H. J., Sun L., Fish K. N., Nelson J. A., Ploegh H. L. Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains. Proc. Natl. Acad. Sci. USA. 93:1996;11327-11333.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11327-11333
    • Jones, T.R.1    Wiertz, E.J.H.J.2    Sun, L.3    Fish, K.N.4    Nelson, J.A.5    Ploegh, H.L.6
  • 22
    • 0025990172 scopus 로고
    • A 15-kilobase-pair region of the human cytomegalovirus genome which includes US1 through US13 is dispensable for growth in cell culture
    • Kollert-Jons A., Bogner E., Radsak K. A 15-kilobase-pair region of the human cytomegalovirus genome which includes US1 through US13 is dispensable for growth in cell culture. J. Virol. 65:1991;5184-5189.
    • (1991) J. Virol. , vol.65 , pp. 5184-5189
    • Kollert-Jons, A.1    Bogner, E.2    Radsak, K.3
  • 23
    • 0031743366 scopus 로고    scopus 로고
    • A cis-repression sequence adjacent to the transcription start site of the human cytomegalovirus US3 gene is required to down regulate gene expression at early and late times after infection
    • Lashmit P. E., Stinski M. F., Murphy E. A., Bullock G. C. A cis-repression sequence adjacent to the transcription start site of the human cytomegalovirus US3 gene is required to down regulate gene expression at early and late times after infection. J. Virol. 72:1998;9575-9584.
    • (1998) J. Virol. , vol.72 , pp. 9575-9584
    • Lashmit, P.E.1    Stinski, M.F.2    Murphy, E.A.3    Bullock, G.C.4
  • 24
    • 0026773361 scopus 로고
    • Human cytomegalovirus contains a tegument protein that enhances transcription from promoters with upstream ATF and Ap-1 cis-acting elements
    • Liu B., Stinski M. F. Human cytomegalovirus contains a tegument protein that enhances transcription from promoters with upstream ATF and Ap-1 cis-acting elements. J. Virol. 66:1992;4434-4444.
    • (1992) J. Virol. , vol.66 , pp. 4434-4444
    • Liu, B.1    Stinski, M.F.2
  • 26
    • 0004250845 scopus 로고    scopus 로고
    • B. N. Fields, D. M. Knipe, & P. M. Howley. Philadephia: Lippincott-Raven
    • Mocarski E. S. Jr. Fields B. N., Knipe D. M., Howley P. M. Fields Virology. 1996;2447-2492 Lippincott-Raven, Philadephia.
    • (1996) Fields Virology , pp. 2447-2492
    • Mocarski E.S., Jr.1
  • 27
    • 0027448623 scopus 로고
    • Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus ori-lyt-dependent DNA replication
    • Pari G. S., Anders D. G. Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus ori-lyt-dependent DNA replication. J. Virol. 67:1993;6979-6988.
    • (1993) J. Virol. , vol.67 , pp. 6979-6988
    • Pari, G.S.1    Anders, D.G.2
  • 28
    • 0030997682 scopus 로고    scopus 로고
    • PIRS1 and pTRS1 are present in human cytomegalovirus virions
    • Romanowski M. J., Garrido-Guerrero E., Shenk T. pIRS1 and pTRS1 are present in human cytomegalovirus virions. J. Virol. 71:1997;5703-5705.
    • (1997) J. Virol. , vol.71 , pp. 5703-5705
    • Romanowski, M.J.1    Garrido-Guerrero, E.2    Shenk, T.3
  • 29
    • 0031014705 scopus 로고    scopus 로고
    • Characterization of the human cytomegalovirus irs1 and trs1 genes: A second immediate-early transcription unit within irs1 whose product antagonizes transcriptional activation
    • Romanowski M. J., Shenk T. Characterization of the human cytomegalovirus irs1 and trs1 genes: A second immediate-early transcription unit within irs1 whose product antagonizes transcriptional activation. J. Virol. 71:1997;1485-1496.
    • (1997) J. Virol. , vol.71 , pp. 1485-1496
    • Romanowski, M.J.1    Shenk, T.2
  • 30
    • 0029817470 scopus 로고    scopus 로고
    • Evidence that the UL84 gene product of human cytomegalovirus is essential for promoting oriLyt-dependent DNA replication and formation of replication compartments in cotransfection assays
    • Sarisky R. T., Hayward G. S. Evidence that the UL84 gene product of human cytomegalovirus is essential for promoting oriLyt-dependent DNA replication and formation of replication compartments in cotransfection assays. J. Virol. 70:1996;7398-7413.
    • (1996) J. Virol. , vol.70 , pp. 7398-7413
    • Sarisky, R.T.1    Hayward, G.S.2
  • 31
    • 0027936351 scopus 로고
    • Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein
    • Sommer M. H., Scully A. L., Spector D. H. Transactivation by the human cytomegalovirus IE2 86-kilodalton protein requires a domain that binds to both the TATA box-binding protein and the retinoblastoma protein. J. Virol. 68:1994;6223-6231.
    • (1994) J. Virol. , vol.68 , pp. 6223-6231
    • Sommer, M.H.1    Scully, A.L.2    Spector, D.H.3
  • 32
    • 0242421666 scopus 로고    scopus 로고
    • Reactivation of latent human cytomegalovirus by allogeneic stimulation of blood cells from healthy donors
    • Söderberg-Nauclér C., Fish K. N., Nelson J. A. Reactivation of latent human cytomegalovirus by allogeneic stimulation of blood cells from healthy donors. Cell. 91:1997;119-126.
    • (1997) Cell , vol.91 , pp. 119-126
    • Söderberg-Nauclér, C.1    Fish, K.N.2    Nelson, J.A.3
  • 33
    • 0028075906 scopus 로고
    • Protein-protein interactions between human cytomegalovirus IE1-580aa and pUL84 in lytically infected cells
    • Spector D. J., Tevethia M. J. Protein-protein interactions between human cytomegalovirus IE1-580aa and pUL84 in lytically infected cells. J. Virol. 68:1994;7549-7553.
    • (1994) J. Virol. , vol.68 , pp. 7549-7553
    • Spector, D.J.1    Tevethia, M.J.2
  • 34
    • 0022624959 scopus 로고
    • 2.2-kilobase class of early transcripts encoded by human cytomegalovirus strain AD169
    • Staprans S. I., Spector D. H. 2.2-kilobase class of early transcripts encoded by human cytomegalovirus strain AD169. J. Virol. 57:1986;591-602.
    • (1986) J. Virol. , vol.57 , pp. 591-602
    • Staprans, S.I.1    Spector, D.H.2
  • 35
    • 0026595150 scopus 로고
    • Transactivation of the cytomegalovirus ICP36 gene promoter requires the α gene product TRS1 in addition to IE1 and IE2
    • Stasiak P. C., Mocarski E. S. Transactivation of the cytomegalovirus ICP36 gene promoter requires the α gene product TRS1 in addition to IE1 and IE2. J. Virol. 66:1992;1050-1058.
    • (1992) J. Virol. , vol.66 , pp. 1050-1058
    • Stasiak, P.C.1    Mocarski, E.S.2
  • 36
    • 0022343026 scopus 로고
    • Autoregulation of the human cytomegalovirus major immediate early gene
    • Stenberg R. M., Stinski M. F. Autoregulation of the human cytomegalovirus major immediate early gene. J. Virol. 56:1985;676-682.
    • (1985) J. Virol. , vol.56 , pp. 676-682
    • Stenberg, R.M.1    Stinski, M.F.2
  • 37
    • 0025909411 scopus 로고
    • Expression of the human cytomegalovirus UL36-38 immediate early region during permissive infection
    • Tenney D. J., Colberg-Poley A. M. Expression of the human cytomegalovirus UL36-38 immediate early region during permissive infection. Virology. 182:1991;199-210.
    • (1991) Virology , vol.182 , pp. 199-210
    • Tenney, D.J.1    Colberg-Poley, A.M.2
  • 38
    • 0027228227 scopus 로고
    • The human cytomegalovirus US3 immediate-early protein lacking the putative transmembrane domain regulates gene expression
    • Tenney D. J., Santomenna L. D., Goudie K. B., Colberg-Poley A. M. The human cytomegalovirus US3 immediate-early protein lacking the putative transmembrane domain regulates gene expression. Nucleic Acids Res. 21:1993;2931-2937.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 2931-2937
    • Tenney, D.J.1    Santomenna, L.D.2    Goudie, K.B.3    Colberg-Poley, A.M.4
  • 39
    • 0029655925 scopus 로고    scopus 로고
    • Regulation of a human cytomegalovirus immediate-early gene (US3) by a silencer-enhancer combination
    • Thrower A. R., Bullock G. C., Bissell J. E., Stinski M. F. Regulation of a human cytomegalovirus immediate-early gene (US3) by a silencer-enhancer combination. J. Virol. 70:1996;91-100.
    • (1996) J. Virol. , vol.70 , pp. 91-100
    • Thrower, A.R.1    Bullock, G.C.2    Bissell, J.E.3    Stinski, M.F.4
  • 40
    • 0023851387 scopus 로고
    • An enhancer element in the short unique region of human cytomegalovirus regulates the production of a group of abundant immediate early transcripts
    • Weston K. An enhancer element in the short unique region of human cytomegalovirus regulates the production of a group of abundant immediate early transcripts. Virology. 162:1988;406-416.
    • (1988) Virology , vol.162 , pp. 406-416
    • Weston, K.1
  • 41
    • 0028321653 scopus 로고
    • UL69 of human cytomegalovirus, an open reading fram with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression
    • Winkler M., Rice S. A., Stamminger T. UL69 of human cytomegalovirus, an open reading fram with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression. J. Virol. 68:1994;3943-3954.
    • (1994) J. Virol. , vol.68 , pp. 3943-3954
    • Winkler, M.1    Rice, S.A.2    Stamminger, T.3
  • 42
    • 0029861953 scopus 로고    scopus 로고
    • A specific subform of the human cytomegalovirus transactivator protein pUL69 is contained within the tegument of virus particles
    • Winkler M., Stamminger T. A specific subform of the human cytomegalovirus transactivator protein pUL69 is contained within the tegument of virus particles. J. Virol. 70:1996;8984-8987.
    • (1996) J. Virol. , vol.70 , pp. 8984-8987
    • Winkler, M.1    Stamminger, T.2
  • 43
    • 0024379417 scopus 로고
    • Posttranscriptional regulation of a class of human cytomegalovirus phosphoproteins encoded by an early transcription unit
    • Wright D. A., Spector D. Posttranscriptional regulation of a class of human cytomegalovirus phosphoproteins encoded by an early transcription unit. J. Virol. 63:1989;3117-3127.
    • (1989) J. Virol. , vol.63 , pp. 3117-3127
    • Wright, D.A.1    Spector, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.