Effects of phosphatidylinositol kinase inhibitors on the activation of the store-operated calcium current ICRAC in RBL-1 cells

Pflugers Archiv European Journal of Physiology

Volumn 442, Issue 3, 2001, Pages 391-395

  Straube, Sebastian ^a   Parekh, Anant B ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

PI kinase; Store operated Ca2+ current

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CALCIUM ION; INOSITOL 1,4,5 TRISPHOSPHATE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVATION; HYDROLYSIS; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; RAT; SECOND MESSENGER; SODIUM CURRENT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 1-PHOSPHATIDYLINOSITOL 4-KINASE; ANDROSTADIENES; ANIMALS; CALCIUM; CHROMONES; ENZYME INHIBITORS; LEUKEMIA, BASOPHILIC, ACUTE; MORPHOLINES; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PHOSPHATIDYLINOSITOL PHOSPHATES; QUERCETIN; RATS; STAUROSPORINE; TUMOR CELLS, CULTURED;

EID: 0034950738     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240100546     Document Type: Article

References (19)

1. A model for receptor-regulated calcium entry
2. Store depletion and calcium influx
3. Calcium signalling and cell proliferation
4. Depletion of intracellular calcium stores activates a calcium current in mast cells
5. Bridging the GAP in inositol 1,3,4,5-tetrakisphosphate signalling
6. Pathways for phosphoinositide synthesis
7. PtdIns-3,4,5-P3: A regulatory nexus between tyrosine kinases and sustained calcium signals
8. Phosphoinositides are required for store-mediated calcium entry in human platelets
9. The effects of interfering with GTP-binding proteins on the activation mechanism of calcium release-activated calcium current
10. CRAC)
11. CRAC in rat basophilic leukaemia cells
12. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
13. 3 and dissociation from calcium release
14. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
15. Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases
16. Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidyl inositol 3,4,5-trisphosphate in neutrophil responses
17. Specificity and mechanism of action of some commonly used protein kinase inhibitors
18. Chromaffin granule-associated phosphatidylinositol 4-kinase activity is required for stimulated secretion
19. Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine