The use of inverse phase gas chromatography to measure the surface energy of crystalline, amorphous, and recently milled lactose

Pharmaceutical Research

Volumn 18, Issue 5, 2001, Pages 662-666

  Newell, Helen E ^a   Buckton, Graham ^a   Butler, David A ^b   Thielmann, Frank ^b   Williams, Daryl R ^b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b USA   (United Kingdom)

Author keywords

Amorphous; Dispersive surface energy; Inverse gas chromatography; Lactose; Milling; Processing induced disorder

Indexed keywords

ALPHA LACTOSE; LACTOSE;

APPARATUS; ARTICLE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE SYNTHESIS; ENERGY; GAS CHROMATOGRAPHY; MEASUREMENT; MOLECULAR INTERACTION; PRIORITY JOURNAL; SURFACE PROPERTY;

ALGORITHMS; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, GAS; CRYSTALLIZATION; DRUG COMPOUNDING; EXCIPIENTS; LACTOSE; SURFACE PROPERTIES;

EID: 0034950053     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011089511959     Document Type: Article

References (18)

1. Increased metastable solubility of milled griseofulvin depending on the formation of disordered surface structure
2. Determination of surface properties and flow characteristics of salbutamol sulphate, before and after micronisation
3. Determination of the surface properties of two batches of salbutamol sulphate by inverse gas chromatography
4. Characterisation of the surface properties of α-lactose monohydrate with inverse gas chromatography, used to detect batch variation
5. A comparison of two contact angle measurement methods and inverse gas chromatography to assess the surface energies of theophylline and caffeine
6. Characterisation of the surface energetics of milled d1-propranolol hydrochloride using inverse gas chromatography and molecular modelling
7. Interpretation of differences in the surface energies of two optical forms of mannitol by inverse gas chromatography and molecular modelling
8. An exploration of inter relationships between contact angle, inverse phase gas chromatography and triboelectric charging
9. Assessment of disorder in crystalline powders - A review of analytical techniques and their application
10. The use of isothermal microcalorimetry in the study of small degrees of amorphous content of powders
11. Gas chromatographic analysis of anomeric composition of lactose
12. The use of thermal techniques to assess the impact of feed concentrations on the amorphous content and polymorphic forms present in spray driedlactose
13. The quantification of small degrees of disorder in lactose using solution calorimetry
14. The adsorption of vapours on Mercury 1. Non-polar substances
15. The role of the interface in carbon fibre-epoxy composites