Understanding the mechanisms by which isoflurane modifies the hyperglycemic response to surgery

Anesthesia and Analgesia

Volumn 93, Issue 1, 2001, Pages 121-127

  Lattermann, Ralph ^a   Schricker, Thomas ^a,d   Wachter, Ulrich ^b   Georgieff, Michael ^b   Goertz, Axel ^c  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF ULM   (Germany)

^c St Marienkrankenhaus   (Germany)

^d ROYAL VICTORIA HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BUPIVACAINE; FATTY ACID; FENTANYL; GLUCAGON; GLUCOSE; GLYCEROL; HYDROCORTISONE; INSULIN; ISOFLURANE; LACTIC ACID; MIDAZOLAM; NORADRENALIN;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; GENERAL ANESTHESIA; GLUCOSE METABOLISM; HUMAN; HYPERGLYCEMIA; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RANDOMIZED CONTROLLED TRIAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SURGERY;

EID: 0034949814     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-200107000-00026     Document Type: Article

References (24)

1. The hyperglycaemic response to surgery: Pathophysiology, clinical implications and modification by the anaesthetic technique
2. The blocking effect of epidural analgesia on the adrenocortical and hyperglycaemic responses to surgery
3. Effect of epidural analgesia on metabolic profiles during and after surgery
4. High- and low-dose fentanyl anaesthesia: Hormonal and metabolic responses during cholecystectomy
5. Propofol/sufentanil anesthesia suppresses the metabolic and endocrine response during, not after, lower abdominal surgery
6. Effects of epinephrine on glucose metabolism in patients with alcoholic cirrhosis
7. Epidural blockade improves substrate utilization after surgery
8. Effect of extra-dural analgesia on glucose metabolism and gluconeogenesis
9. The effect of extradural blockage upon glucose and urea kinetics in surgical patients
10. Isoflurane and whole body leucine, glucose and fatty acid metabolism in dogs
11. Determination of Krebs cycle metabolic carbon exchange in vivo and its use to estimate the individual contributions of gluconeogenesis and glycogenolysis to overall glucose output in man
12. The significance of altered gluconeogenesis in surgical catabolism
13. Quantitative analysis of amino acid oxidation and related gluconeogenesis in humans
14. Carbohydrate metabolism and requirements
15. Combined hormonal infusion stimulates the metabolic response to injury
16. The independent metabolic effect of halothane and isoflurane anaesthesia
17. Effect of isoflurane anaesthesia and surgery on carbohydrate metabolism and plasma cortisol levels in man
18. Quantifying gluconeogenesis during fasting
19. Inhibition of lipolysis causes suppression of endogenous glucose production independent of changes in insulin
20. Role of gluconeogenesis in epinephrine-stimulated hepatic glucose production in humans
21. Carbohydrate and lipid metabolism in cirrhosis: Evidence that hepatic uptake of gluconeogenic precursors and of free fatty acids depends on effective hepatic flow
22. Kinetics of glycerol uptake by the perfused rat liver: Membrane transport, phosphorylation and effect on NAD redox level
23. Haemodynamics and oxygen consumption in the dog during high epidural block with special reference to the splanchnic region
24. Intestinal hemodynamics during laparotomy: Effects of thoracic epidural anesthesia and dopamine in humans