Polymerase slippage at vesicular stomatitis virus gene junctions to generate poly(A) is regulated by the upstream 3′-AUAC-5′ tetranucleotide: Implications for the mechanism of transcription termination

Journal of Virology

Volumn 75, Issue 15, 2001, Pages 6901-6913

  Barr, J N ^a   Wertz, G W ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; NUCLEOTIDE; POLYADENYLIC ACID;

ARTICLE; BASE PAIRING; GENETIC TRANSCRIPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA SYNTHESIS; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION; TRANSCRIPTION TERMINATION; VESICULAR STOMATITIS VIRUS;

ANIMALS; BACTERIOPHAGE T7; CELL LINE; CRICETINAE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, VIRAL; GENES, VIRAL; GENOME, VIRAL; HUMANS; POLY A; RECOMBINATION, GENETIC; RIBONUCLEASE H, CALF THYMUS; RNA REPLICASE; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; TEMPLATES, GENETIC; TRANSCRIPTION, GENETIC; VESICULAR STOMATITIS-INDIANA VIRUS; VIRAL PROTEINS;

EID: 0034948006     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.15.6901-6913.2001     Document Type: Article

References (42)

1. Sequential transcription of the genes of vesicular stomatitis virus
2. Order of transcription of genes of vesicular stomatitis virus
3. cis-acting signals involved in termination of vesicular stomatitis virus mRNA synthesis include the conserved AUAC and the U7 signal for polyadenylation
4. Role of the intergenic dinucleotide in vesicular stomatitis virus RNA transcription
5. Polymerase errors accumulating during natural evolution of the glycoprotein gene of vesicular stomatitis virus Indiana serotype isolates
6. Complete nucleotide sequence of the leader RNA synthesized in vitro by vesicular stomatitis virus
7. A unique RNA species involved in initiation of vesicular stomatitis virus RNA transcription in vitro
8. The Sendai virus P gene expresses both an essential protein and an inhibitor of RNA synthesis by shuffling modules via mRNA editing
9. Reconstitution studies detect a single polymerase entry site on the vesicular stomatitis virus genome
10. Dissociation and reconstitution of the transcriptase and template activities of vesicular stomatitis virus B and T virions
11. The versatility of paramyxovirus RNA polymerase stuttering
12. Two nucleotides immediately upstream of the essential A6G3 slippery sequence modulate the pattern of G insertions during Sendai virus mRNA editing
13. Intervening polyadenylate sequences in RNA transcripts of vesicular stomatitis virus
14. Polycistronic vesicular stomatitis virus RNA transcripts
15. Aberrant polyadenylation by a vesicular stomatitis virus mutant is due to an altered L protein
16. Increased synthesis of polycistronic mRNA associated with increased polyadenylation by vesicular stomatitis virus
17. Polyadenylation of vesicular stomatitis virus mRNA dictates efficient transcription termination at the intercistronic gene junctions
18. Localized attenuation and discontinued synthesis during vesicular stomatitis virus transcription
19. Plus and minus strand leader RNAs in negative strand virus-infected cells
20. Overlapping signals for transcription and replication at the 3′ terminus of the vesicular stomatitis virus genome
21. Termination and slippage by bacteriophage T7 RNA polymerase
22. Detection of in vivo synthesis of polycistronic mRNAs of vesicular stomatitis virus
23. Structure of the gene N: Gene NS intercistronic junction in the genome of vesicular stomatitis virus
24. Assembly and transcription of synthetic vesicular stomatitis virus nucleocapsids
25. The RNA-DNA hybrid maintains the register of transcription by preventing backtracking of RNA polymerase
26. Infectious defective interfering particles of VSV from transcripts of a cDNA clone
27. Complete intergenic and flanking gene sequences from the genome of vesicular stomatitis virus
28. Giant heterogeneous polyadenylic acid on vesicular stomatitis virus mRNA synthesized in vitro in the presence of S-adenosylhomocysteine
29. The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing
30. The minimal conserved transcriptional stop-start signal promotes stable expression of a foreign gene in vesicular stomatitis virus
31. Site on the vesicular stomatitis virus genome specifying polyadenylation and the end of the L gene mRNA
32. In vivo transcription of the 5′-terminal extracistronic region of vesicular stomatitis virus RNA
33. Promoter analysis of the vesicular stomatitis virus RNA polymerase
34. The length and sequence composition of vesicular stomatitis virus intergenic regions affect mRNA levels and the site of transcript initiation
35. Mutational analyses of the intergenic dinucleotide and the transcriptional start sequence of vesicular stomatitis virus (VSV) define sequences required for efficient termination and initiation of VSV transcripts
36. Transcript initiation and 5′-end modifications are separable events during vesicular stomatitis virus transcription
37. Two mRNAs that differ by two nontemplated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5
38. Determination of molar ratios of vesicular stomatitis virus induced species in BHK-21 cells
39. GP mRNA of Ebola virus is edited by the Ebola virus polymerase and by T7 and vaccinia virus polymerases
40. Identification of a minimal size requirement for termination of vesicular stomatitis virus mRNA: Implications for the mechanism of transcription
41. Regulation of RNA synthesis by the genomic termini of vesicular stomatitis virus: Identification of distinct sequences essential for transcription but not replication
42. Efficient recovery of infectious vesicular stomatitis virus entirely from cDNA clones