The role of Asn14 in the stability and conformation of the reactive-site loop of winged bean chymotrypsin inhibitor: Crystal structures of two point mutants Asn14→Lys and Asn14→Asp

Protein Engineering

Volumn 14, Issue 5, 2001, Pages 349-357

  Ravichandran, S ^a   Dasgupta, J ^a   Chakrabarti, C ^a   Ghosh, S ^b   Singh, M ^b   Dattagupta, J K ^a  

^a SAHA INSTITUTE OF NUCLEAR PHYSICS   (India)

^b INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Reactive site loop; Site directed mutagenesis; Winged bean chymotrypsin inhibitor; X ray structure

Indexed keywords

CHYMOTRYPSIN INHIBITOR; MUTANT PROTEIN; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; HYDROGEN BOND; MOLECULAR CLONING; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DETERMINATION; PROTEIN STABILITY; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

PHASEOLUS (ANGIOSPERM); PSOPHOCARPUS TETRAGONOLOBUS;

EID: 0034941318     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/14.5.349     Document Type: Article

References (45)