Kinetics of folate turnover in pregnant women (second trimester) and nonpregnant controls during folic acid supplementation: Stable-isotopic labeling of plasma folate, urinary folate and folate catabolites shows subtle effects of pregnancy on turnover of folate pools

Journal of Nutrition

Volumn 131, Issue 7, 2001, Pages 1928-1937

  Gregory III, J F ^a   Caudill, M A ^a   Jeffery Opalko, F ^a   Bailey, L B ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Catabolism; Folate; Humans; Kinetics; Pregnancy; Stable isotopes

Indexed keywords

4 AMINOBENZOIC ACID; ACEDOBEN; FOLIC ACID; ISOTOPE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIET SUPPLEMENTATION; FEMALE; FOLATE METABOLISM; FOLIC ACID BLOOD LEVEL; HUMAN; SECOND TRIMESTER PREGNANCY; TURNOVER TIME; URINALYSIS; VITAMIN INTAKE;

EID: 0034938814     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/131.7.1928     Document Type: Article

References (33)

1. Chemical and nutritional aspects of folate research: Analytical procedures, methods of folate synthesis, stability and bioavailability of dietary folates
2. Modeling of folate metabolism
3. Neural-tube defects
4. New standard for dietary folate intake in pregnant women
5. Folic acid: Influence on the outcome of pregnancy
6. Folic acid metabolism in pregnancy
7. The elucidation of the mechanism of folate catabolism in the rat
8. The turnover, catabolism and excretion of folate administered at physiological concentrations in the rat
9. The quantitative analysis of endogenous folate catabolites in human urine
10. Accelerated folate breakdown in pregnancy
11. The relationship between increased folate catabolism and the increased requirement for folate in pregnancy
12. Folate catabolism in pregnant and nonpregnant women consuming controlled folate intakes
13. 2]folic acid: Isotopic labeling of urinary folate and the catabolite para-acetamidobenzoylglutamate indicates slow, intake-dependent, turnover of folate pools
14. Urinary excretion of deuterium-labeled folate and the metabolite p-aminobenzoylglutamate in humans
15. Relationship between urinary excretion of p-aminobenzoylglutamate and folate status of growing rats
16. Urinary excretion of folate catabolites responds to changes in folate intake more slowly than plasma folate and homocysteine concentration and lymphocyte DNA methylation in postmenopausal women
17. Kinetic modeling of folate metabolism using chronic administration of deuterium-labeled folic acid in adult men
18. Folate status response to controlled folate intake in pregnant women
19. 2] folic acid: Extent and specificity of deuterium labeling
20. Microbiological assay of folates
21. Chemical synthesis of deuterated monoglutamate and in vivo assessment of urinary excretion of deuterated folates in man
22. Preparation of stable-isotopically labeled folates for in vivo investigation of folate absorption and metabolism
23. 13C]methionine
24. SAAM II: Simulation, analysis and modeling software
25. Unmetabolized folic acid in serum: Acute studies in subjects consuming fortified food and supplements
26. Purification and properties of a folate catabolizing enzyme
27. Acetylation of p-aminobenzoylglutamate, a folic acid catabolite, by recombinant human arylamine N-acetyltransferase and U937 cells