Vitamin D receptor gene polymorphisms are associated with breast cancer risk in a UK Caucasian population

British Journal of Cancer

Volumn 85, Issue 2, 2001, Pages 171-175

  Bretherton Watt, D ^a   Given Wilson, R ^c   Mansi, J L ^a   Thomas, V ^b   Carter, N ^b   Colston, K W ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c Duchess of Kent Breast Screening Unit   (United Kingdom)

Author keywords

Breast cancer; Caucasian; Human; Polymorphism; Receptor; Vitamin D

Indexed keywords

VITAMIN D RECEPTOR;

3' UNTRANSLATED REGION; ADULT; AGED; ARTICLE; BREAST CANCER; CANCER RISK; CAUCASIAN; CONTROLLED STUDY; DNA POLYMORPHISM; ENVIRONMENTAL FACTOR; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; HEREDITY; HUMAN; MAJOR CLINICAL STUDY; MAMMOGRAPHY; PRIORITY JOURNAL; STATISTICAL ANALYSIS; UNITED KINGDOM;

ADULT; AGED; BREAST NEOPLASMS; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GREAT BRITAIN; HUMANS; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, CALCITRIOL;

EID: 0034935175     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2001.1864     Document Type: Article

References (34)

1. A novel vitamin D3 analog, 22-oxa-1,25-dihydroxyvitamin D3 inhibits the growth of breast cancer in vivo and in vitro without causing hypercalcaemia
2. Familial versus sporadic breast cancer
3. Topical vitamin D analogue (calcipotriol) therapy in advanced breast cancer
4. Vitamin D receptor (VDR) and parathyroid hormone mRNA levels correspond to polymorphic VDR alleles in human parathyroid tumours
5. 1,25-Dihydroxyvitamin D3 inhibitory effect on the growth of two human breast cancer cell lines (MCF-7, BT-20)
6. Possible role for vitamin D in controlling breast cancer cell proliferation
7. Are vitamin D receptor polymorphisms associated with bone mineral density? A meta analysis
8. Association of a vitamin D receptor polymorphism with sporadic breast cancer development
9. Post-transcriptonal gene regulatory mechanisms in eukaryotes: An overview
10. No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer
11. Vitamin D receptor 3' untranslated region polymorphisms: Lack of effect on mRNA stability
12. Effects of 1,25-dihydroxyvitamin D3 on cell cycle kinetics of T47D human breast cancer cells
13. Vitamin D receptor gene start codon polymorphism (Fokl) and bone mineral density: Interaction with age, dietary calcium and 3' end region polymorphisms
14. Vitamin D receptor gene polymorphisms: Analysis of ligand binding and hormone responsiveness in cultured skin fibroblasts
15. A phase I study of the vitamin D analogue EB 1089 in patients with advanced breast and colorectal cancer
16. The vitamin D receptor start codon polymorphism (Fokl) and bone mineral density in premenopausal American black and white women
17. Vitamin D receptor polymorphism, bone mineral density, and osteoporotic vertebral fracture: Studies in a UK population
18. Polymorphisms in the 3′ and 5′ ends of the VDR gene are associated with breast cancer risk in African-American women
19. Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor
20. Strength of linkage disequilibrium between two vitamin D receptor markers in five ethnic groups: Implications for association studies
21. Vitamin D receptor genotype and breast cancer in Latinas
22. Vitamin D derivatives in combination with 9-cis retinoic acid promote active cell death in breast cancer cells
23. EB 1089, a synthetic analogue of vitamin D3, induces apoptosis in breast cancer cells in vivo and in vitro
24. The BsmI vitamin D receptor restriction fragment polymorphism (bb) influences the effect of calcium intake on bone mineral density
25. Association of breast cancer gene progression with a vitamin D receptor gene polymorphism
26. Vitamin D receptor polymorphisms, circulating vitamin D metabolites and risk of prostate cancer in United States physicians
27. Quantification of vitamin D receptor mRNA by competative polymerase chain reaction in PBMC: Lack of correspondence with common allelic variants
28. Prediction of bone mineral density from vitamin D receptor alleles
29. Vitamin D receptor gene polymorphism is associated with metastatic breast cancer
30. Association of prostate cancer with vitamin D receptor gene polymorphism
31. Influence of the vitamin D receptor gene alleles on bone mineral density in postmenopausal and osteoporotic women
32. Vitamin D receptor: No evidence for allele-specific mRNA stability in cells which are heterozygous for the TaqI restriction enzyme polymorphism
33. Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens
34. Prevalence of disease-related DNA polymorphisms among participants in a large cancer prevention trial