Nitric oxide and glioma: A target for novel therapy?

British Journal of Neurosurgery

Volumn 15, Issue 3, 2001, Pages 213-220

  Shinoda, J ^a   Whittle, I R ^a  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Cerebral blood flow; Glioma; Nitric oxide; Nitric oxide synthase

Indexed keywords

ANTINEOPLASTIC AGENT; FREE RADICAL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

BLOOD VESSEL PERMEABILITY; BRAIN BLOOD FLOW; CANCER INVASION; CARCINOGENESIS; CENTRAL NERVOUS SYSTEM; CLINICAL TRIAL; DRUG DISPOSITION; ENZYME ASSAY; GLIOMA; HUMAN; IMMUNOMODULATION; NEOVASCULARIZATION (PATHOLOGY); NERVE CELL PLASTICITY; NEUROTRANSMISSION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; THROMBOCYTE AGGREGATION INHIBITION; TREATMENT PLANNING; TUMOR BLOOD FLOW; TUMOR CELL DESTRUCTION; VASODILATATION;

ANIMALS; BRAIN NEOPLASMS; CENTRAL NERVOUS SYSTEM; GLIOMA; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RATS; TUMOR CELLS, CULTURED;

EID: 0034932342     PISSN: 02688697     EISSN: None     Source Type: Journal    
DOI: 10.1080/02688690120057628     Document Type: Review

References (71)

1. Stimulation of guanylate cyclase by sodium nitroprusside, nitroglycerin and nitric oxide in various tissue preparations and comparison to the effects of sodium azide and hydroxylamine
2. Guanylate cyclase: Activation by azide, nitro compounds, nitric oxide, and hydroxyl radical and inhibition by hemoglobin and myoglobin
3. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
4. Endothelium derived relaxing and contractor factors
5. Endothelium-derived nitric oxide: Actions and properties
6. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
7. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium dependent relaxation
8. Synthesis of nitric oxide in CNS glial cells
9. Nitric oxide and the cerebral virculation
10. Nitric oxide: Mediator, murderer, and medicine
11. Nitric oxide in the central nervous system
12. Nitric oxide in acute ischemic stroke: A target for neuroprotection
13. The multifaceted roles of nitric oxide in cancer
14. Role of nitric oxide in growth of solid tumours: A balancing act
15. Mapping of neural nitric oxide synthase in the rat suggests frequent co-localization with NADPH diaphorase but not soluble guanylyl cyclase, and novel paraneural functions for nitrinergic signal transduction
16. Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS
17. The anti-aggregating properties of vascular endothelium: Interactions between prostacyclin and nitric oxide
18. Inhibition of iNOS induction in C6 glioma cells by glucocorticoids
19. Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells
20. 6-methylguanine-DNA-methyltransferase activity: Analysis of three residues at or near the methyl acceptor site
21. 6-methylguanine-DNA-methyltransferase
22. Nitric oxide inhibits DNA ligase activity potential mechanisms for NO mediated DNA damage
23. Cytochemical demonstration of nitric oxide synthase and 5nucleotidase in human glioblastoma
24. Nitric oxide synthase expression in malignant glioma: A histochemical study
25. Expression of nitric oxide synthase in human central nervous system tumours
26. The expression of nitric oxide synthases in human brain tumours and peritumoural areas
27. Differential expression of inducible nitric oxide synthase mRNA in human brain tumours
28. Expression of heme oxygenase and inducible nitric oxide synthase mRNA in human brain tumors
29. Mycobacterium tuberculosis enhances iNOS mRNA expression and HIV replication in human astrocytoma cells
30. The generation of nitric oxide participates in gIFN-induced MHC class II antigen expression by cultured astrocytoma cells
31. Synthesis and biological effects of NO in malignant glioma cells: Modulation by cytokines including CD95L and TGF-b, dexamethasone, and p53 gene transfer
32. Increased brain tumor microvessel permeability after intracarotid bradykinin infusion is mediated by nitric oxide
33. Activation of type III nitric oxide synthase in astrocytes following a neurotropic viral infection
34. Induction of nitric oxide synthase in glial cells
35. Induction of calcium-independent nitric oxide synthase activity in primary rat astrocyte cultures
36. Induction of nitric oxide synthase in rat C6 glioma cells
37. Serotonin 5-HT2A receptor activation inhibits cytokine-stimulated inducible nitric oxide synthase in C6 glioma cells
38. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production
39. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cell
40. Endothelial cell production of nitric oxides in response to interfern in combination with tumor necrosis factor, interleukin-1, or endotoxin
41. Cytokines, endotoxin and glucocorticoids regulate the expression of inducible nitric oxide synthase in hepatocytes
42. Differential suppression of glial nitric oxide synthase induction by structurally related tyrosine kinase inhibitors
43. Mechanisms for nitric oxide-induced cell death: Involvement of apoptosis
44. Inverse correlation between expression of inducible nitric oxide synthase activity and production of metastasis in K-1735 murine melanoma cells
45. Nitric oxide reduces tumor cell adhesion to isolated rat post-capillary venules
46. Microglial cells induce cytotoxic effects toward colon carcinoma cells: Measurement of tumor cytotoxicity with a gamma-glutamyl transpeptidase assay
47. Nitric oxide regulates vascular cell adhesion molecule 1 gene expression and redox-sensitive transcriptional events in human vascular endothelial cells
48. Induction of vascular endothelial growth factor by nitric oxide in human glioblastoma and hepatocellular carcinoma cells
49. Reciprocal relation between VEGF and NO in the regulation of endothelial integrity
50. Lipopolysaccharide regulate both serotonin-and thrombin-induced intracellular calcium mobilization in rat C6 glioma cells: Possible involvement of nitric oxide synthase-mediated pathway
51. Cerebrovascular autoregulation in response to hypertension induced by NG-nitro-L-arginine methyl ester
52. SIN-1 reverses attenuation of hypercapnic cerebrovasodilatation by nitric oxide synthase inhibitors
53. Effects of nitric oxide modulation on tumour blood flow and microvascular permeability in C6 glioma
54. Nitric oxide synthase is expressed in experimental malignant glioma and influences tumour bloodflow
55. Effects of nitric oxide manipulation on the disposition of platinum in an experimental glioma model
56. Enhanced tumor uptake of carboplatin and survival in glioma-bearing rats by intracarotid infusion of bradykinin analog, RMP-7
57. Increased delivery of a new cisplatin analogue (254-s) in a rat brain tumor by an intracarotid infusion of bradykinin
58. Intracarotid low dose bradykinin infusion selectively increases tumor permeability through activation of bradykinin B2 receptors in malignant gliomas
59. Intracarotid infusion of RMP-7, a bradykinin analog, and transport of gallium-68 ethylenediamine tetraacetic acid into human gliomas
60. A phase I study of intravenous RMP-7 with carboplatin in patients with progression of malignant glioma
61. Enhanced delivery of boronophenylalanine for neutron capture therapy of brain tumors using the bradykinin analog Cereport (Receptor-Mediated Permeabilizer-7)
62. Intravenous RMP-7 increases delivery of ganciclovir into rat brain tumors and enhances the effects of herpes simplex virus thymidine kinase gene therapy
63. Long-term survival in a rodent brain tumor model by bradykinin-enhanced intra-arterial delivery of a therapeutic herpes simplex virus vector
64. Potentiation of anti-proliferative effect of nitroprusside by ascorbate in human brain tumor cells
65. Mechanisms of potentiation of LY83583-induced growth inhibition by sodium nitroprusside in human brain tumor cells
66. Growth inhibition and radiosensitization of cultured glioma cells by nitric oxide generating agents
67. The effects of chronic nitric oxide synthase expression on glioma pathophysiology
68. Is tumorgenecity dependent on glioma expression of iNOS? Studies using antisense knockout of iNOS expression in C6 glioma cell line
69. Tumourgenicity dependence of C6 cells on iNOS; studies using the rodent striatal implantation model
70. Suppression of tumourogenicity and metastases of human renal carcinoma cell by infection with retroviral vectors harbouring the murine-inducible NOS gene
71. The effects of dexamethasone on vascular permeability, blood flow and iNOS expression in experimental glioma