Pathogenetic aspects of IgA nephropathy

Nephron

Volumn 88, Issue 3, 2001, Pages 193-198

  Rantala, Immo ^a   Mustonen, Jukka ^a,b   Hurme, Mikko ^a,b   Syrjänen, Jaana ^a,b   Helin, Heikki ^a  

^a TAMPERE UNIVERSITY HOSPITAL   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROLIFERATION; DISEASE ACTIVITY; GLOMERULUS FILTRATION RATE; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY FUNCTION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

ANTIGEN-ANTIBODY COMPLEX; AUTOANTIGENS; GLOMERULONEPHRITIS, IGA; GLYCOSYLATION; HUMANS; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; INTERLEUKINS; KIDNEY GLOMERULUS;

EID: 0034931101     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000045989     Document Type: Review

References (59)

1. Immune mechanisms in glomerular IgA deposition
2. Mediterranean diet and primary IgA nephropathy
3. Mucosal immunity in primary glomerulonephritis. III. Study of intestinal permeability
4. Small bowel T cells, HLA class II antigen DR, and GroEL stress protein in IgA nephropathy
5. Murine bone marrow IgA responses to orally administrated sheep erythrocytes
6. Pathogenesis of IgA nephropathy
7. Deficient IgA1 immune response to nasal cholera toxin subunit B in primary IgA nephropathy
8. Humoral immune response in patients with IgA and IgM glomerulonephritis
9. Immune response to oral polio vaccine in patients with IgA glomerulonephritis
10. Increased dimeric IgA producing B cells in the bone marrow in IgA nephropathy determined by in situ hybridisation
11. Serum IgA and production of IgA by peripheral blood and bone marrow lymphocytes in patients with primary IgA nephropathy. Evidence for the bone marrow as a source of mesangial IgA
12. Expression of J chain mRNA in duodenal IgA plasma cells in IgA nephropathy
13. IgA glomerulonephritis (Berger's disease). Evidence of high serum levels of polymeric IgA
14. Increase of IgA specific helper T alpha cells in patients with IgA nephropathy
15. Studies of the molecular basis of IgA production, subclass regulation and class-switch recombination in IgA nephropathy patients
16. Lymphocyte subpopulations and immunoglobulin production in IgA nephropathy
17. Role of CD40-CD40-ligand interaction in Ig-isotype switching
18. IL-1 receptor antagonist (IL-1Ra) plasma levels are coordinately regulated by both IL-1Ra and IL-1β genes
19. Evidence for genetic factors in the development of IgA nephropathy
20. Interleukin-1 receptor antagonist allele: Is it a genetic link between Henoch-Schönlein nephritis and IgA nephropathy?
21. Increased excretion of tumor necrosis factor-alpha and interleukin-1-beta in urine from patients with IgA nephropathy and Schönlein-Henoch purpura
22. In situ expression of cytokines in IgA nephritis
23. Interleukin-1 in crescentic glomerulonephritis
24. Increased production of interleukin-2 and IL-2 receptors in IgA nephropathy
25. Cytokine production by peripheral blood mononuclear cells in IgA nephropathy
26. Serum levels of interleukin-2 receptor and disease activity in patients with IgA nephropathy
27. Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG
28. Analysis of IgA1 O-glycans in IgA nephropathy by fluorophore-assisted carbohydrate electrophoresis
29. O-linked oligosaccharide on IgA1 hinge region in IgA nephropathy. Fundamental study for precise structure and possible role
30. Galactosylation of N- and O-linked carbohydrate moieties of IgA1 and IgG in IgA nephropathy
31. Modulation of mesangial cell reactivity in aberrantly glycosylated IgA
32. Binding capacity of serum IgA to jacalin in patients with IgA nephropathy using jacalin-coated microplates
33. IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23
34. Circulating immune complexes in IgA nephropathy consists of IgA1 with galactose-deficient hinge region and antiglycan antibodies
35. Humoral immunity against the proline-rich peptide epitope of the IgA1 hinge region in IgA nephropathy
36. Association of asialo-galactosyl-β-1,3-N-acetylgalactosamine on the hinge with conformational instability of Jacalin-reactive immunoglobulin A1 in immunoglobulin A nephropathy
37. Studies on IgA antiglobulins in IgA nephropathy
38. IgA antibodies to dietary antigens and lectin binding IgA in sera from Italian, Australian, and Japanese IgA nephropathy patients
39. Clearance kinetics and fate of macromolecular IgA in patients with IgA nephropathy
40. Downregulation of Fcα receptors on blood cells of IgA nephropathy patients: Evidence for negative regulatory role of serum IgA
41. Patients with IgA nephropathy have circulating anti-basement membrane antibodies reacting with structures common to collagen I, II and IV
42. Circulating complexes containing IgA and fibronectin in patients with primary IgA nephropathy
43. Underglycosylation of IgA1 hinge plays a certain role for its glomerular deposition in IgA nephropathy
44. Direct evidence for decreased sialylation and galactosylation of human serum IgA1 Fc O-glycosylated hinge peptides in IgA nephropathy by mass spectrometry
45. IgA interaction with carboxy-terminal 43-kD fragment of fibronectin in IgA nephropathy
46. Evidence for a specific IgA receptor in rat and human mesangial cells
47. Glomerular FcαR expression and disease activity in IgA nephropathy
48. The role of the carbohydrate chains in complement (C3) fixation by solid phase-bound human IgA
49. Chronicity index and mesangial IgG deposition are risk factors for hypertension and renal failure in early IgA nephropathy
50. Intraglomerular C3 synthesis in human kidney detected by in situ hybridization
51. Correlation between glomerular injuries and the existence of cytokines in glomeruli of patients with IgA nephropathy
52. Expression of TGF-β receptors type I and II in human glomerulonephritis
53. Detection of apoptotic cells in glomeruli of patients with IgA nephropathy
54. Specificity of eluted antibody from renal tissues of patients with IgA nephropathy
55. Familial IgA nephropathy
56. Occurrence of mesangial IgA and IgM deposits in a control necropsy population
57. Immunoglobulin and complement deposition in glomeruli of 756 subjects who had committed suicide or met with a violent death
58. HLA-DQ gene polymorphism in primary IgA nephropathy in three European populations
59. IgA nephropathy: Analysis of the natural history, important factors in the progression of renal disease, and a review of the literature