Physiological, subjective and reinforcing effects of oral and intravenous cocaine in humans

Psychopharmacology

Volumn 156, Issue 4, 2001, Pages 435-444

  Smith, Brandi J ^a   Jones, Hendree E ^b   Griffiths, Roland R ^b  

^a UNIVERSITY OF MISSOURI   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cocaine; Multiple choice procedure; Physiological effect; Reinforcing effect; Route of administration; Subjective effect

Indexed keywords

COCAINE; PLACEBO;

ADULT; ARTICLE; BLOOD PRESSURE; CLINICAL ARTICLE; CLINICAL TRIAL; COCAINE DEPENDENCE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG POTENCY; FEMALE; HEART RATE; HUMAN; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; REINFORCEMENT;

ADMINISTRATION, ORAL; ADULT; AFFECT; ANALYSIS OF VARIANCE; BLOOD PRESSURE; COCAINE; COCAINE-RELATED DISORDERS; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HEART RATE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; REINFORCEMENT (PSYCHOLOGY);

EID: 0034929125     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100740     Document Type: Article

References (33)

1. Rate of increase of plasma drug level influences subjective response in humans
2. Subjective and behavioral effects of diazepam depend on its rate of onset
3. Transitions in the route of cocaine administration - Characteristics, direction and associated variables
4. Low-dose oral cocaine in humans: Acquisition of discrimination and time-course of effects
5. Relationship between self-reported drug effects and their reinforcing effects: Studies with stimulant drugs
6. Cardiovascular and subjective effects of intravenous cocaine administration in humans
7. A comparison of the subjective and cardiovascular effects of cocaine and lidocaine in humans
8. Acute tolerance development to the cardiovascular and subjective effects of cocaine
9. Effects of desipramine maintenance on cocaine self-administration by humans
10. Self-administration of cocaine by humans: Choice between smoked and intravenous cocaine
11. Cardiovascular effects of cocaine in humans: Laboratory studies
12. Multiple-choice procedure: An efficient approach for investigating drug reinforcement in humans
13. Validation of the multiple-choice procedure for investigating drug reinforcement in humans
14. Self-administration of smoked cocaine
15. Influence of an alternative reinforcer on human cocaine self-administration
16. Subjective and physiological effects of intravenous nicotine and cocaine in cigarette smoking cocaine abusers
17. Cocaine and metabolite concentrations in plasma during repeated oral administration: Development of a human laboratory model of chronic cocaine use
18. Subjective responses during continuous infusion of cocaine
19. Marihuana smoking increases plasma cocaine levels and subjective reports of euphoria in male volunteers
20. Abecarnil and alprazolam in humans: Behavioral, subjective, and reinforcing effects
21. Alprazolam absorption kinetics affects abuse liability
22. Discriminative stimulus, self-reported, and cardiovascular effects of orally administered cocaine in humans
23. Effects of d-amphetamine and caffeine in humans under a cocaine discrimination procedure
24. Effects of cocaine alone and in combination with bromocriptine in human cocaine abusers
25. Effects of cocaine alone and in combination with mazindol in human cocaine abusers
26. Acute physiological and behavioral effects of oral cocaine in humans: A dose-response analysis
27. Caffeine reinforcement: The role of withdrawal
28. Modulation of drug reinforcement by behavioral demands following drug ingestion
29. Enhancing caffeine reinforcement by behavioral requirements following drug ingestion
30. Oral cocaine: Plasma concentrations and central effects
31. Intranasal and oral cocaine kinetics