Acute physiological and behavioral effects of oral cocaine in humans: A dose-response analysis

Drug and Alcohol Dependence

Volumn 55, Issue 1-2, 1999, Pages 1-12

  Rush, Craig R ^a   Baker, Robert W ^a   Wright, Ken ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Behavioral effects; Cocaine; Drug abuse; Humans; Physiological effects

Indexed keywords

COCAINE; PLACEBO;

ARTICLE; BEHAVIOR; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG ABUSE; FEMALE; HEART RATE; HUMAN; HUMAN EXPERIMENT; INTRACARDIAC DRUG ADMINISTRATION; MALE; MEAN ARTERIAL PRESSURE; MOOD; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PERFORMANCE; PRIORITY JOURNAL; QUESTIONNAIRE; SYSTOLIC BLOOD PRESSURE; VOLUNTEER;

ACUTE DISEASE; ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; COCAINE; COCAINE-RELATED DISORDERS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HEART RATE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; PSYCHOMOTOR PERFORMANCE; QUESTIONNAIRES; TIME FACTORS;

EID: 0032934321     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0376-8716(98)00164-1     Document Type: Article

References (53)

1. Di Marino, M.E., Haberny, K.A., Felch, L.J., Walsh, S.L., Preston, L.K., Bigelow, G.E., 1998. Development of a subjective rating scale sensitive to acute cocaine administration. In: Harris, L. (Ed.), Problems of Drug Dependence, 1997. National Institute on Drug Abuse Research Monograph Series , pp. 139.
2. Dudish-Poulsen S.A., Hatsukami D.K. Dissociation between subjective and behavioral responses after cocaine stimuli presentation. Drug Alcohol Depend. 47:1997;1-9.
3. Falk J.L., Siris A., Lau C.E. Conditions sufficient for the production of oral cocaine or lidocaine self-administration in preference to water. Drug Alcohol Depend. 40:1996;241-247.
4. Farré M., De La Torre R., Llorente M. et al. Alcohol and cocaine interactions in humans. J. Pharmacol. Exp. Ther. 266:1993;1364-1373.
5. Fischman M.W. Behavioral pharmacology of cocaine in humans. Grabowski J. Cocaine: Pharamcology, Effects, and Treatment of Abuse. 1984;72-91 National Institute on Drug Abuse Research Monograph 50, US Government Printing Office, Washington, DC.
6. Fischman, M.W., 1989. Relationship between self-reported drug effects and their reinforcing effects: studies with stimulant drugs. In: Fischman, M.W., Mellow, N.K. (Eds.), Testing for Abuse Liability of Drugs in Humans, National Institute on Drug Abuse Research Monograph 92, National Institute on Drug Abuse, Public Health Service: Alcohol, Drug Abuse, and Mental Health Administration, Rockville, MD, US DHHS (ADM) 89-1613, 1989 pp. 211-230.
7. Fischman M.W., Schuster C.R. Cocaine self-administration in humans. Fed. Proc. 41:1982;241-246.
8. Fischman M.W., Schuster C.R., Javaid J., Hatano Y., Davis J. Acute tolerance development to the cardiovascular and subjective effects of cocaine. J. Pharmacol. Exp. Ther. 235:1985;677-682.
9. Fischman M.W., Foltin R.W., Nestadt G., Pearlson G.D. Effects of despiramine on maintenance of cocaine self-administration by humans. J. Pharmacol. Exp. Ther. 253:1990;760-770.
10. Fischman M.W., Schuster C.R., Resnekov L. et al. Cardiovascular and subjective effects of intravenous cocaine administration in humans. Arch. Gen. Psychiatry. 33:1976;983-989.
11. Foltin R.W., Fischman M.W. Smoked and intravenous cocaine in humans: acute tolerance, cardiovascular, and subjective effects. J. Pharmacol. Exp. Ther. 257:1991;247-261.
12. Foltin R.W., Fischman M.W. Self-administration of cocaine by humans: choice between smoked and intravenous cocaine. J. Pharmacol. Exp. Ther. 261:1992;841-849.
13. Foltin R.W., Fischman M.W. Effects of buprenorphine on the self-adminstration of cocaine by humans. Behav. Pharmacol. 5:1994;79-89.
14. Foltin R.W., Fischman M.W., Levin F.R. Cardiovascular effects of cocaine in humans: laboratory studies. Drug Alcohol Depend. 37:1995;193-210.
15. George F.R., Elmer G.I., Meisch R.A., Goldberg S.R. Orally delivered cocaine functions as a positive reinforcer in C57BL/6J mice. Pharmacol. Biochem. Behav. 38:1991;897-903.
16. Griffiths R.R., Rush C.R., Puhala K.A. Validation of the multiple-choice procedure for investigating drug reinforcement in humans. Exp. Clin. Psychopharmacol. 4:1996;97-106.
17. Griffiths R.R., Troisi II J.R., Silverman K., Mumford G.K. Multiple-choice procedure: an efficient approach for investigating drug reinforcement in humans. Behav. Pharmacol. 4:1993;3-13.
18. Hatsukami D., Keenan R., Carroll M. et al. A method for delivery of precise doses of smoked cocaine-base to humans. Pharmacol. Biochem. Behav. 36:1990;1-7.
19. Hatsukami D.K., Pentel P.R., Glass J. et al. Methodological issues in the administration of multiple doses of smoked cocaine-base in humans. Pharmacol. Biochem. Behav. 47:1994;531-540.
20. Hatsukami D.K., Thompson T.N., Pentel P.R., Flygare B.K., Carroll M.E. Self-amdinistration of smoked cocaine. Exp. Clin. Psychopharmacol. 2:1994;115-126.
21. Higgins S.T., Bickel W.K., Hughes J.R. Influence of an alternative reinforcer on human cocaine self-administration. Life Sci. 55:1994;179-187.
22. Higgins S.T., Bickel W.K., Hughes J.R., Lynn M., Capeless M.A., Fenwick J.W. Effects of intranasal cocaine on human learning, performance, and physiology. Psychopharmacology. 102:1990;451-458.
23. Higgins S.T., Roll J.M., Bickel W.K. Alcohol pretreatment increases preference for cocaine over monetary reinforcement. Psychopharmacology. 123:1996;1-8.
24. Higgins S.T., Rush C.R., Hughes J.R., Bickel W.K., Lynn M., Capless M.A. Acute behavioral and cardiac effects of cocaine and alcohol combinations in humans. Psychopharmacology. 111:1993;285-294.
25. Inaba T. Cocaine: pharmacokinetics and biotransformation in man. Can. J. Physiol. Pharmacol. 67:1989;1154-1175.
26. Jasinski D. Assessment of the abuse potentiality of morphine-like drugs (methods used in man). Martin W.R. Drug Addiction I. 1977;197-258 Springer-Verlag, New York.
27. Javaid J.I., Fischman M.W., Schuster C.R., Dekirmenjian H., Davis J.M. Cocaine plasma concentration: relation of physiological and subjective effects in humans. Science. 202:1978;227-228.
28. Johanson C.E., Fischman M.W. The pharmacology of cocaine related to its abuse. Pharmacol. Rev. 41:1989;3-52.
29. Johanson C.E., Schuster C.R. Cocaine. Bloom F.E., Kupfer D.J. Psychopharmacology: The Fourth Generation. 1995;1685-1697 Raven Press, New York.
30. Martin W.R., Sloan J.W., Sapiro J.D., Jasinski D.R. Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man. Clin. Pharmacol. Ther. 12:1971;245-258.
31. McLeod D.R., Griffiths R.R., Bigelow G.E., Yingling J.E. An automated version of the digit symbol substitution test (DSST). Behav. Res. Methods Instr. 14:1982;463-466.
32. Meisch R.A., George F.R., Lemaire G.A. Orally delivered cocaine as a reinforcer for rhesus monkeys. Pharmacol. Biochem. Behavior. 35:1990;245-249.
33. Meisch R.A., Stewart R.B. Relative reinforcing effects of different doses of orally delivered cocaine. Drug Alcohol Depend. 37:1995;141-147.
34. Oliveto A.H., Bickel W.K., Hughes J.R., Shea P.J., Higgins S.T., Fenwick J.W. Caffeine drug discrimination in humans: acquisition, specificity, and correlation with self-reports. J. Pharmacol. Exp. Ther. 261:1992;885-894.
35. Oliveto A.H., McCance-Katz E., Singha A., Hameedi F., Kosten T.R. Effects of d-amphetamine and caffeine in humans under a cocaine discrimination procedure. Behav. Pharmacol. 9:1998;207-217.
36. Oliveto A.H., Rosen M.I., Woods S.W., Kosten T.R. Discriminative stimulus, self-reported, and cardiovascular effects of orally administered cocaine in humans. J. Pharmacol. Exp. Ther. 272:1995;231-241.
37. Perez-Reyes M., DiGuiseppi S., Ondrusek G., Jeffcoat A.R., Cook C.E. Free-base cocaine smoking. Clin. Pharmacol. Ther. 32:1982;459-465.
38. Post R.M., Kotin J., Goodwin F.K. The effects of cocaine on depressed patients. Am. J. Psychiatry. 131:1974;511-517.
39. Preston K.L., Sullivan J.T., Berger P., Bigelow G.E. Effects of cocaine alone and in combination with mazindol in human cocaine abusers. J. Pharmacol. Exp. Ther. 267:1993;296-307.
40. Preston K.L., Sullivan J.T., Strain E.C., Bigelow G.E. Effects of cocaine alone and in combination with bromocriptine in human cocaine abusers. J. Pharmacol. Exp. Ther. 262:1992;279-291.
41. Resnick R.B., Kestenbaum R.S., Schwartz L.K. Acute systemic effects of cocaine in man: a controlled study by intranasal and intravenous routes. Science. 195:1977;696-698.
42. Rowbotham M.C., Jones R.T., Benowitz N.L., Jacob III P. Trazodone-oral cocaine interactions. Arch. Gen. Psychiatry. 41:1984;895-899.
43. Selzer M.L. The Michigan alcoholism screening test: the quest for a new diagnostic instrument. Am. J. Psychiatry. 127:1971;1653-1658.
44. Skinner H.A. The drug abuse screening test. Addict. Behav. 7:1982;363-371.
45. Stillman R., Jones R.T., Moore D., Walker J., Welm S. Improved performance 4 h after cocaine. Psychopharmacology. 110:1993;415-420.
46. Substance Abuse and Mental Health Services Administration (SAMHSA), 1996. Preliminary Estimates from the Drug Abuse: Preliminary Estimates of Drug-Related Emergency Department Episodes. Advance Report No. 17, http://www.health.org/pubs/96dawn/ar17d.htm.
47. Substance Abuse and Mental Health Services Administration (SAMHSA), 1997a. Preliminary result from the 1996 National Household Survey on Drug Abuse. US Department of Health and Humans Services, Substance Abuse and Mental Health Services Administration Office of Applied Studies, http://www.health.org/pubs/nhsda/96hhs/rtst1010.htm.
48. Substance Abuse and Mental Health Services Administration (SAMHSA), 1997b. National Admissions to Substance Abuse Treatment Services: The Treatment Episode Data Set (TEDS), 1992-1995. Advance Report No. 12, http://www.samhsa.gov/oas/teds/tedsweb2.gif.
49. Tang M., Falk J.L. Oral self-administration of cocaine: chronic excessive intake by schedule induction. Pharmacol. Biochem. Behavior. 28:1987;517-519.
50. Van Dyke C., Jatlow P., Ungerer J., Barash P.G., Byck R. Oral cocaine: plasma concentrations and central effects. Science. 200:1978;211-213.
51. Walsh, S.L., Jufer, R., Cone, E., Bigelow, G.E., 1997. Repeated dosing with oral cocaine in humans: pharmacodynamic and pharmacokinetic effects. In: Harris, L., (Ed.), Problems of Drug Dependence, National Institute on Drug Abuse Research Monograph Series, pp. 218.
52. Walsh S.L., Preston K.L., Sullivan J.T., Fromme R., Bigelow G.E. Fluoxetine alters the effects of intravenous cocaine in humans. J. Clin. Psychopharmacol. 14:1994;396-407.
53. Wilkinson P., Van Dyke C., Jatlow P., Barash P., Byck R. Intranasal and oral cocaine kinetics. Clin. Pharmacol. Ther. 27:1980;386-394.