Overexpression of cdk inhibitor p16INK4a by adenovirus vector inhibits cardiac hypertrophy in vitro and in vivo: A novel strategy for the gene therapy of cardiac hypertrophy

Journal of Molecular and Cellular Cardiology

Volumn 33, Issue 8, 2001, Pages 1493-1504

  Nozato, Toshihiro ^a   Ito, Hiroshi ^a   Watanabe, Masazumi ^a   Ono, Yuichi ^a   Adachi, Susumu ^a   Tanaka, Hiroyuki ^a   Hiroe, Michiaki ^a   Sunamori, Makoto ^a   Marum, Fumiaki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Adenovirus vector; Cardiac hypertrophy; Cell cycle; Cyclin dependent kinase (cdk) inhibitor; Gene therapy

Indexed keywords

ALPHA ACTIN; ATRIAL NATRIURETIC FACTOR; CYCLIN DEPENDENT KINASE INHIBITOR; ENDOTHELIN 1; LEUCINE; MESSENGER RNA; PROTEIN P16; VIRUS VECTOR;

ADENOVIRUS; ANIMAL CELL; AORTA COARCTATION; ARTICLE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE THERAPY; GENETIC CODE; HEART LEFT VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; MORPHOMETRICS; MORTALITY; NONHUMAN; PRIORITY JOURNAL;

ADENOVIRIDAE;

EID: 0034926065     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2001.1412     Document Type: Article

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