Sensitivity to exogenous GH and reversibility of the reduced IGF-I gene expression in aging rats

European Journal of Endocrinology

Volumn 145, Issue 1, 2001, Pages 73-85

  Velasco, B ^a   Cacicedo, L ^a   Melian, E ^a   Fernandez Vazquez G ^a   Sanchez Franco F ^a  

^a HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE BINDING PROTEIN; GROWTH HORMONE RECEPTOR; MESSENGER RNA; RECOMBINANT GROWTH HORMONE; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HORMONE BLOOD LEVEL; HORMONE SENSITIVITY; HYPOPHYSIS; IMMUNOREACTIVITY; KIDNEY PARENCHYMA; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TESTIS;

EID: 0034925077     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/eje.0.1450073     Document Type: Article

References (49)

1. Nyctohemeral growth hormone profiles in young and aged men: Correlation with somatomedin-C levels
2. The growth hormone deficiency syndrome in adults
3. Human growth hormone and human aging
4. Effects of human growth hormone in men over 60 years old
5. Clinical aspects of growth hormone deficiency in adults
6. Growth hormone treatment of abdominally obese men reduces abdominal fat mass, improves glucose and lipoprotein metabolism and reduces diastolic blood pressure
7. Long-term growth hormone treatment in growth hormone deficient adults
8. Evidence for an endogenous ultradian rhythm governing growth hormone secretion in the rat
9. Decreased pulsatile release of growth hormone in old male rats
10. Growth hormone gene expression and secretion in aging rats is age dependent and not age-associated weight increase related
11. Cellular localization of somatomedin (insulin-like growth factor) messenger RNA in the human fetus
12. Conditional knockout of mouse insulin-like growth factor-1 gene using Cre/loxP system
13. Effects of aging and dietary restriction on tissue protein synthesis: Relationship to plasma insulin-like growth factor-1
14. Growth hormone restores protein synthesis in skeletal muscle of old male rats
15. Influence of age and long-term dietary restriction on plasma insulin-like growth factor I (IGF-I), IGF-I gene expression and IGF-I binding proteins
16. Molecular cloning of rat insulin-like growth factor I complementary ribonucleic acids: Differential messenger ribonucleic acid processing and regulation by growth hormone in extrahepatic tissues
17. Growth hormone regulates the abundance of insulin-like growth factor I mRNA in adult rat liver
18. Growth hormone dependence of somatomedin-C/insulin-like growth factor I and insulin-like growth factor II messenger ribonucleic acids
19. Genes for insulin-like growth factor I and II are expressed in senescent tissues
20. Quantitative comparison of insulin-like growth factor mRNA levels in human and rat tissues analyzed by solution hybridization assay
21. Structure of the Mr 140 000 growth hormone-dependent insulin-like growth factor binding protein complex: Determination by reconstitution and affinity-labeling
22. Basal and Growth hormone-induced hepatic messenger ribonucleic acid expression of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 is independent of hypersinsulinemia and increased energy status obese Zucker rat
23. Sexual dimorphism in the control of growth hormone secretion
24. Growth hormone receptors - Their structure, localization and role
25. A specific growth hormone-binding protein in human plasma: Initial characterization
26. Identification and characterization of a specific binding proteins for growth hormone in normal human sera
27. Recombinant human growth hormone-binding protein fails to enhance the in vivo bioactivity of human growth hormone in normal rats
28. Evidence for the specific binding of growth hormone to a receptor-like protein in rabbit serum
29. Initial characterization and sexual dimorphism of serum growth hormone-binding protein in adult rats
30. GH binding to liver in young and old female rats: Relation to somatomedin-C secretion
31. Decreases in growth hormone receptor signal transduction contribute to the decline in insulin-like growth factor I gene expression with age
32. The insulin-like growth factor I generation test: Resistance to growth hormone with aging and estrogen replacement therapy
33. Distribution and regulation of rat insulin-like growth factor I messenger ribonucleic acids encoding alternative carboxyterminal E-peptides: Evidence for differential processing and regulation in liver
34. Growth hormone (GH) stimulates insulin-like growth factor-I (IGF-I) and IGF binding protein but not GH receptor gene in liver of juvenile rats
35. Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone
36. p1B15: A cDNA clone of the rat mRNA encoding cyclophilin
37. Cloning and characterization of the growth hormone-dependent insulin-like growth factor binding protein 3 (IGFBP-3) in the rat
38. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
39. Expression and regulation of insulin-like growth factor I (IGF-I) and IGF-binding protein messenger ribonucleic acid levels in tissues of hypophysectomized rats infused with IGF-I and growth hormone
40. Growth hormone induces somatostatin and insulin-like growth factor I gene expression in the cerebral hemispheres of aging rats
41. Different effects of intermittent and continuous growth hormone (GH) administration on serum somatomedin-C/insulin-like growth factor I and liver GH receptors in hypophysectomized rats
42. Tissue distribution and regulation of insulin-like growth factor (IGF) binding protein-3 messenger ribonucleic acid (mRNA) in the rat: Comparison with IGF-I mRNA expression
43. Dual regulation of insulin-like growth factor I expression during renal hypertrophy
44. Growth hormone regulates steroidogenic acute regulatory protein expression and steroidogenesis in Leydig cell progenitors
45. The effects of GH on the Leydig cell response to chorionic gonadotropin in boys with hypopituitarism
46. Testicular function in hypopituitarism
47. Regulation of rat growth hormone receptor gene expression
48. Differential regulation by growth hormone (GH) of insulin-like growth factor I and GH receptor/binding protein gene expression in rat liver
49. Time course and mechanism of growth hormone's negative feedback effect on its own spontaneous release