Clinical expert round table discussion (session 3) at the Margaux Conference on critical illness: The role of activated protein C in severe sepsis

Critical Care Medicine

Volumn 29, Issue 7 SUPPL., 2001, Pages

  Bernard, G ^a   Artigas, A ^a   Dellinger, P ^a   Esmon, C ^a   Faist, E ^a   Faust, S N ^a   Fisher C J , Jr ^a   Fumagalli, R ^a   Grinnell, B W ^a   Sprung, C ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; DROTRECOGIN; THROMBIN; THROMBOMODULIN;

BLOOD CLOTTING; CLINICAL TRIAL; CONFERENCE PAPER; CRITICAL ILLNESS; DISEASE SEVERITY; DRUG EFFICACY; ENDOTHELIUM INJURY; HUMAN; INFLAMMATION; MORTALITY; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SEPSIS; THROMBOSIS;

EID: 0034923009     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200107001-00025     Document Type: Conference Paper

References (15)

1. Recombinant human activated protein C (rhAPC) produces a trend toward improvement in morbidity and 28 day survival in patients with severe sepsis
2. Efficacy and safety of recombinant human activated protein C for severe sepsis
3. Results of the multicenter phase III clinical trial in severe sepsis in the Kyparsept trial
4. Use of protein C concentrate, heparin, and haemodiafiltration in Meningococcus-induced purpura fulminans
5. Protein C prevents the coagulopathic and lethal effects of E. coli infusion in the baboon
6. The effect of heparin on multiple organ failure and disseminated intravascular coagulation in a sepsis model
7. The cell mediated events that control blood coagulation and vascular injury
8. Tumor necrosis factor suppresses the thrombomodulin gene in endothelial cells
9. Tissue factor pathway of coagulation in sepsis
10. Inflammation and thrombosis: Mutual regulation linked through the protein C anticoagulant pathway
11. Human protein C inhibits selectin-mediated cell adhesion: Role of unique fucosylated oligosaccharide
12. Activated protein C prevents LPS-induced pulmonary vascular injury by inhibiting cytokine production
13. Molecular basis for host-pathogen interaction in septic shock
14. Homozygous protein C deficiency: 7-Year follow-up
15. Septic shock, multiple organ failure, and disseminated intravascular coagulation: Compared patterns of antithrombin III, protein C, and protein S deficiencies