MRI investigation of hydration and heterogeneous degradation of aliphatic polyesters derived from lactic and glycolic acids: A controlled drug delivery device

Magnetic Resonance Imaging

Volumn 19, Issue 3-4, 2001, Pages 521-523

  Djemai, A ^a   Gladden, L F ^a   Booth, J ^b   Kittlety, R S ^b   Gellert, P R ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Autocatalytic reaction; MRI; PGLA; Polymer degradation

Indexed keywords

ALIPHATIC COMPOUND; CARBOXYL GROUP; GLYCOLIC ACID; LACTIC ACID; POLYESTER; POLYGLACTIN;

CATALYSIS; CONCENTRATION RESPONSE; CONFERENCE PAPER; DEGRADATION; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERIZATION; PRIORITY JOURNAL;

CATALYSIS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; GLYCOLATES; LACTIC ACID; MAGNETIC RESONANCE IMAGING; POLYESTERS; WATER;

EID: 0034920866     PISSN: 0730725X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0730-725X(01)00283-1     Document Type: Conference Paper

References (6)

1. A nuclear magnetic resonance imaging study of the effect of incorporating a macromolecular drug in poly(glycolic acid-co-DL-lactic acid)
2. Magnetic resonance imaging analysis of molecular mobility during dissolution of poly(vinyl alcohol) in water
3. Quantitative NMR imaging study of the mechanism of drug release from swelling hydroxypropylmethylcellulose tablets
4. Hydrolytic degradation characteristics of aliphatic polyesters derived from lactic and glycolic acids
5. Structure-property relationships in the case of the degradation of massive poly (α-hydroxy acids) in aqueous media. Part 1: Poly (DL-lactic acid)
6. Quantitative nuclear magnetic resonance imaging of liquids in swelling polymers