Acute activation of gp130 gene expression in bone marrow stromal cells by contact with myeloma-derived lymphoblastic cell line ARH77 cell membranes

Journal of Interferon and Cytokine Research

Volumn 21, Issue 3, 2001, Pages 157-166

  Juneja, H S ^a   Lee, S ^a   Thomazy, V ^a   Shipley, G ^a   Davies, P J A ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; CYTOKINE; GLYCOPROTEIN GP 130; INTERLEUKIN 6; MEMBRANE RECEPTOR; MESSENGER RNA;

ARTICLE; BONE MARROW CELL; CELL CONTACT; CELL INTERACTION; CELL LINE; CELL MEMBRANE; CONTROLLED STUDY; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSCRIPTION; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; LYMPHOBLAST; MYELOMA CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STROMA CELL; TUMOR CELL;

ANTIGENS, CD; BONE MARROW CELLS; CELL COMMUNICATION; CELL MEMBRANE; CELLS, CULTURED; COCULTURE TECHNIQUES; CYCLOHEXIMIDE; CYTOKINE RECEPTOR GP130; DOWN-REGULATION; HUMANS; INTERLEUKIN-6; MEMBRANE GLYCOPROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STROMAL CELLS; TUMOR CELLS, CULTURED; UP-REGULATION;

EID: 0034918414     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/107999001750133177     Document Type: Article

References (31)

1. Primary tumor cells of myeloma patients induce interleukin-6 secretion in long-term bone marrow cultures
2. Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion
3. Interdependence between cytokines and cell adhesion molecules to induce interleukin-6 production by stromal cells in myeloma
4. Metalloproteinases in multiple myeloma: Production of matrix metalloproteianse-9 (MMP-9), activation of pro MMP-2, and induction of MMP-1 by myeloma cells
5. Long-term bone marrow cultured stromal cells regulate myeloma tumor growth in vitro: Studies with primary tumor cells and LTBMC-dependent cell lines
6. Factors affecting the in vitro evolution of a myeloma cell line
7. Establishment and characterization of a human stroma-dependent myeloma cell line (MM5.1) and its stroma-independent variant (MM5.2)
8. Phenotypic and molecular analysis of six human cell lines derived from patients with plasma cell dyscrasia
9. Characterization of adhesion molecules on human myeloma cell lines
10. Cell surface expression and functional significance of adhesion molecules on human myeloma-derived cell lines
11. Production of free light chains of immunoglobulin by a hematopoietic cell line derived from a patient with multiple myeloma
12. Established immunoglobulin producing myeloma (IgE) and lymphoblastoid (IgG) cell lines from IgE myeloma patient
13. Establishment of a human plasma cell line in vitro
14. Functionally distinct human marrow stromal cell lines immortalized by transduction with the human papillomavirus E6/E7 genes
15. Heterotypic adherence between human B-lymphoblastic and pre-B-lymphoblastic cells and marrow stromal cells is a biphasic event. Integrin very late antigen-4-α mediates only the early phase of the heterotypic adhesion
16. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms
17. Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy
18. Real time quantitative PCR
19. A novel method for real time quantitative RT-PCR
20. 36B4 cDNA used as an estradiol-independent mRNA control is the cDNA for human acidic ribosomal phosphoprotein PO
21. gp130 and the interleukin-6 family of cytokines
22. A labile inhibitor blocks immunoglobulin kappa-light-chain gene transcription in pre-B leukemic cell line
23. Multiple myeloma cell adhesion-induced interleukin-6 expression in bone marrow stromal cells involves activation of NF-κB
24. Regulation of cytokine and growth factor gene expression in human bone marrow stromal cells transfected with simian virus 40
25. gp130, the cytokine common signal-transducer of interleukin-6 cytokine family, is down-regulated in T cells in vivo by interleukin-6
26. Differential regulation of interleukin-6 receptor and gp130 gene expression in rat hepatocytes
27. Selective upregulation of cytokine receptor subchain and their intracellular signaling molecules after peripheral nerve injury
28. IL-6 receptor independent stimulation of human gp130 by viral IL-6
29. New insights into the cellular, biochemical, and molecular basis of postmenopausal and senile osteoporosis: Roles of IL-6 and gp130
30. Human marrow stromal cells: Response to interleukin-6 (IL-6) and control of IL-6 expression
31. Regulation of bone marrow stromal cell differentiation by cytokines whose receptors share the gp130 protein