Regulation of preglomerular microvascular 20-hydroxyeicosatetraenoic acid levels by salt depletion

Medical Science Monitor

Volumn 7, Issue 4, 2001, Pages 567-572

  Carroll, Mairead A ^a   Kemp, Rowena ^a   Cheng, Monica K ^a   McGiff, John C ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Angiotensin II; Cyclooxygenase; Cytochrome P450; Eicosanoids; Renal microvessels; Salt depletion

Indexed keywords

ANGIOTENSIN; CYCLOOXYGENASE 2; ENDOTHELIN 1; HYDROXYICOSATETRAENOIC ACID; RAS PROTEIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROLYTE EXCRETION; ENZYME INDUCTION; FEEDBACK SYSTEM; GENE ACTIVATION; GLOMERULUS; KIDNEY BLOOD VESSEL; KIDNEY CIRCULATION; KIDNEY TUBULE ABSORPTION; MALE; MITOGENICITY; NEPHRON; NONHUMAN; PROSTAGLANDIN METABOLISM; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SALT INTAKE; SECOND MESSENGER; SODIUM DEPLETION; VASOCONSTRICTION;

ANIMALS; ARACHIDONIC ACID; CAPILLARIES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLOOXYGENASE 2; CYTOCHROME P-450 ENZYME SYSTEM; HYDROXYEICOSATETRAENOIC ACIDS; ISOENZYMES; KIDNEY GLOMERULUS; MALE; MASS SPECTROMETRY; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE; VENULES;

EID: 0034915171     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Integrating multiple paracrine regulators of renal microvascular dynamics
2. Angiotensin II (AII) stimulates release of cytochrome P450-derived hydroxyeicosatetraenoic acids from rat renal microvessels
3. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles
4. Renal cytochrome P-450-arachidonic acid metabolism: Localization and hormonal regulation in SHR
5. Structural identification of cytochrome P450-dependent arachidonate metabolites formed by rabbit medullary thick ascending limb cells
6. Cytochrome P-450-dependent HETEs: Profile of biological activity and stimulation by vasoactive peptides
7. 20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries
8. Cytochrome P450-derived renal HETEs: Storage and release
9. 20-Hydroxyeicosatetraenoic acid is excreted as a glucuronide conjugate in human urine
10. Actions of epoxygenase metabolites on the preglomerular vasculature
11. Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites
12. Regulation of cyclooxygenase expression in the kidney by dietary salt intake
13. Nitric oxide regulates renal cortical cyclooxygenase-2 expression
14. 5, 6-Epoxyeicosatrienoic acid, a novel arachidonate metabolite
15. Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2
16. 5, 6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis
17. The 5, 6-epoxyeicosatrienoic acid, a novel arachidonate metabolite: Mechanism of vasoactivity in the rat
18. Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet