Improved dissolution and cytotoxicity of camptothecin incorporated into oxidized-cellulose microspheres prepared by spray drying

Pharmaceutical Development and Technology

Volumn 6, Issue 3, 2001, Pages 459-467

  Kumar, Vijay ^a   Kang, Jichao ^a   Hohl, Raymond J ^b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

Aqueous oxidized cellulose colloids; Camptothecin; Microspheres; Oxidized cellulose; Spray drying

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CARBOXYL GROUP; GLYCEROL; MACROGOL 400; MACROGOL 6000; MICROSPHERE; OXIDIZED CELLULOSE; PLASTICIZER;

ARTICLE; CYTOTOXICITY; DESICCATION; DISPERSION; DOSE RESPONSE; DRUG MANUFACTURE; DRUG RELEASE; DRUG SOLUBILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; LYMPHOID CELL; PARTICLE SIZE; PH; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; CELLULOSE, OXIDIZED; DRUG SCREENING ASSAYS, ANTITUMOR; HEMOSTATICS; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; SOLUBILITY; TUMOR CELLS, CULTURED;

EID: 0034913489     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-100002254     Document Type: Article

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