Polymeric microparticles prepared by spraydrying a drugcontaining, aqueous colloidal acrylic polymer dispersion, Eudragit RS30D

S.T.P. Pharma Sciences

Volumn 7, Issue 6, 1997, Pages 521-528

  Quo, X ^a,b   Bodmeier, R ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Aqueous colloidal polymer dispersion; Eudragit rs30d; Latex; Microencapsulation; Microparticles spraydrying

Indexed keywords

CHLORPHENIRAMINE MALEATE; EUDRAGIT; IBUPROFEN; NAPROXEN;

ARTICLE; COLLOID; DELAYED DRUG RELEASE; DISPERSION; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG MANUFACTURE; DRUG PELLET; DRUG SOLUBILITY; MICROENCAPSULATION; PARTICLE SIZE; SPHERONIZATION; TABLET COMPRESSION; TABLET DISINTEGRATION;

EID: 0031544672     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. BENITA S. Microencapsulation. Marcel Dekker, New York, 1996.
2. DEASY P.B. Microencapsulation and Related Drug Processes. Marcel Dekker, New York, 1984.
3. McGINITY J.W. Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms. 2nd edition, Marcel Dekker, New York, 1996.
4. BODM'EIER R. and WANG J. Microencapsulation of drugs with aqueous colloidal polymerdiepersions. J. Pharm. Sei., 82, 191194, 1993.
5. CHANG C.M. and BODMEIER R. Organic solventfree polymeric microspheres prepared from .aqueous colloidal polymer dispersions by a w/o emulsion technique. Int. J. Pharm., 130, 187194, 1996.
6. MASTERS K. SprayDrying Handbook. 5th edition, Longman Sei. & Tech., London, 1991.
7. JUNGINGER H. and SCHWABE D. Spraydried products with the properties of microcapsules. Acta Pharm. Technol., 27, 151157, 1981.
8. NIELSEN F. Spraydrying pharmaceuticals. Manuf. Chem., 53,3839, 1982.
9. TRAUE J. and KALA H. Application of polyacrylate dispersion for spraydrying of phénobarbital. I : Production and in vitro investigation of microcapsules. Pharmazie, 39, 233237, 1984.
10. TRAUE J. and KALA H.Application of polyacrylate dispersion for spraydrying of phénobarbital. Il : In vitro test of tablets with phénobarbital microcapsules. Pharmazie, 39,331333,1984.
11. TAKEUCHI H., HANDA T. and KAWASHIMA Y. Controlledrelease theophylline tablet with acrylic polymers prepared by spraydrying technique in aqueous system. Drug Dev. Ind. Pharm., 15, 19992016, 1989.
12. LI N S. Y. and KAO Y.H. Tablet formulation study of spraydried sodium diclofenacentericcoated microcapsules. Pharm. Res., 8,919924,1991.
13. PALMIERI G.F., WEHRLE P. and STAMM A. Evaluation of spraydrying as a method to prepare microparticles for controlled drug release. Drug Dev. Ind. Pharm., 20, 28592879, 1994.
14. WHEATLEYT.andSTEUERNAGELC.R.Latexemulsionsfor controlled drug delivery. In : Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, J.W. McGinity Ed., 2nd edition, Marcel Dekker, New York, 1996, pp. 154.
15. BODMEIER R., CHEN H., TYLE P. and JAROSZ P. Spontaneous formation of drugcontaining acrylic nanoparticles. J. Microencapsulation, 8, 161170, 1991.
16. LEHMANN K. Chemistry and application properties of polymethacrylate coating systems. In : Aqueous Polymeric Coatings for Pharmaceutical Dosage Forms, J.W. McGinity Ed., 2nd edition, Marcel Dekker, New York, 1996, pp. 101176.
17. KOSITPRAPA U., HERRMANN J. and BODMEIER R. Interactions between cationic drugs and the anionic surfactant, sodium lauryl sulfate. Pharm. Res., 10, S153, 1993.
18. BODMEIER R. and PAERATAKULO.Processandformulation variables affecting the drug release from chlorpheniramine maleate beads coated with commercial and selfprepared ethyl cellulose pseudolatexes. Int. J. Pharm., 70, 5968,1991.