DNA damage by 3,6-dihydropyrazine-2,5-dipropanoic acid, the cyclic dimerization product of 5-aminolevulinic acid

Biological Chemistry

Volumn 382, Issue 6, 2001, Pages 913-918

  Teixeira, P C ^a   Onuki, J ^a   Medeiros, M H G ^a   Dornemann D ^a   Di Mascio, P ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

5 Aminole vulinic acid; 8 Oxo 7,8 dihydro 2 deoxyguanosine; Acute intermittent porphyria; Copper; Dihydropyrazine; DNA damage; Primary liver cancer; Reactive oxygen species; Strand breaks

Indexed keywords

3,6 DIHYDROPYRAZINE 2,5 DIPROPIONIC ACID; 8 HYDROXYDEOXYGUANOSINE; AMINOLEVULINIC ACID; ANTIOXIDANT; CATALASE; COPPER ION; DEOXYGUANOSINE; DNA; HEME; LIPOSOME; METAL; METAL CHELATE; PLASMID DNA; POLYAMINE DERIVATIVE; PROPIONIC ACID DERIVATIVE; REACTIVE OXYGEN METABOLITE; SPERMIDINE; SPERMINE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ACUTE INTERMITTENT PORPHYRIA; AGAR GEL ELECTROPHORESIS; ARTICLE; CATALYSIS; CELL STRUCTURE; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONGENITAL ERYTHROPOIETIC PORPHYRIA; CONTROLLED STUDY; DIMERIZATION; DNA DAMAGE; DNA STRAND BREAKAGE; ELECTROCHEMICAL DETECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LEAD POISONING; LIVER CANCER; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SYNTHESIS;

AMINOLEVULINIC ACID; COPPER; CYCLIZATION; DEOXYGUANOSINE; DIMERIZATION; DNA DAMAGE; OXIDATION-REDUCTION; OXIDOREDUCTASES; PLASMIDS; PORPHYRIAS; PROPIONIC ACIDS; PYRAZINES;

EID: 0034912620     PISSN: 14316730     EISSN: None     Source Type: Journal    
DOI: 10.1515/BC.2001.113     Document Type: Article

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