New compounds derived from dihydropyrazines having DNA strand-breakage activity

Tetrahedron

Volumn 55, Issue 3, 1999, Pages 675-686

  Yamaguchi, Tadatoshi ^a   Eto, Masashi ^b   Harano, Kazunobu ^b   Kashige, Nobuhiro ^c   Watanabe, Kenji ^c   Ito, Shigeru ^d  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

^c FUKUOKA UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Dimerization; Ene reactions; Pyrazines; X ray crystallography

Indexed keywords

(2,3,5) 1,2 ETHYLENE IMINO 1,7,10 TRIAZA 2,3,6 TRIMETHYL 3 HYDROXY SPIRO[4,5]DECAN 6 ENE; 2,3 DIHYDRO 2,2,5,6 TETRAMETHYLPYRAZINE; 2,3 DIHYDRO 2,5,6 TRIMETHYLPYRAZINE; 2,3 DIHYDRO 5,6 DIMETHYLPYRAZINE; 2,4A,7,9A TETRAMETHYLCYCLOHEXANO[1,2 E:4,5 E']DIPIPERAZIN 6 ENE; 4A,9A 2,2,4A,7,7,9A HEXAMETHYLCYCLOHEXANO[1,2 E:4,5 E']DIPIPERAZIN 6 ENE; HYDANTOIN DERIVATIVE; PYRAZINE DERIVATIVE; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ARTICLE; CALCULATION; CHEMICAL REACTION; DIMERIZATION; DNA STRAND BREAKAGE; DRUG SYNTHESIS; ISOMERISM; NUCLEAR MAGNETIC RESONANCE; PLASMID; POLARIZATION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; X RAY ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0033555847     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(98)01079-5     Document Type: Article

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