Isolation of a novel zinc finger repressor that regulates the kidney-specific CLC-K1 promoter

Kidney International

Volumn 60, Issue 2, 2001, Pages 416-421

  Uchida, S ^a   Sasaki, S ^a   Marumo, F ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Chloride channel; GA cis element; Gene promoter; Kidney enriched Kr ppel like factor; Myc associated zinc finger protein; Tissue specific expression; Transcription

Indexed keywords

CIS ACTING ELEMENT; GENE PRODUCT; PROTEIN CLC K1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

BINDING SITE; CELL SPECIFICITY; CONFERENCE PAPER; DNA LIBRARY; GEL MOBILITY SHIFT ASSAY; GENE CONTROL; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HUMAN; KIDNEY; MOLECULAR CLONING; NONHUMAN; ONCOGENE MYC; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN ISOLATION; TISSUE DISTRIBUTION; TISSUE SPECIFICITY; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ZINC FINGER GENE;

EID: 0034911771     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1755.2001.060002416.x     Document Type: Conference Paper

References (13)

1. Molecular cloning of a chloride channel that is regulated by dehydration and expressed predominantly in kidney medulla
2. Two isoforms of a chloride channel predominantly expressed in thick ascending limb of Henle's loop and collecting ducts of rat kidney
3. Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III
4. Overt nephrogenic diabetes insipidus in mice lacking the CLC-K1 chloride channel
5. Localization of rat CLC-K2 chloride channel mRNA in the kidney
6. Isolation and characterization of kidney-specific ClC-K1 chloride channel gene promoter
7. Isolation and characterization of kidney-specific CLC-K2 chloride channel gene promoter
8. Transcriptional regulation of the CLC-K1 promoter by myc-associated zinc finger protein and kidney-enriched Kruppel-like factor, a novel zinc finger repressor
9. MAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and termination
10. Pur-1, a zinc-finger protein that binds to purine-rich sequences, transactivates an insulin promoter in heterologous cells
11. A myc-associated zinc finger protein binding site is one of four important functional regions in the CD4 promoter
12. Phenylethanolamine N-methyltransferase gene expression
13. The serotonin 1a receptor gene contains a TATA-less promoter that responds to MAZ and Spl