A polymeric system for the intra-oral delivery of an anti-fungal agent

Biomaterials

Volumn 22, Issue 17, 2001, Pages 2319-2324

  Patel, M P ^a   Cruchley, A T ^a   Coleman, D C ^b   Swai, H ^a   Braden, M ^a   Williams, D M ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Candida; Chlorhexidine; Intra oral; PEM THFM; Polymeric delivery system

Indexed keywords

CURING; FUNGI; GRAVIMETRIC ANALYSIS; TURBIDITY; ULTRAVIOLET SPECTROMETERS;

COLONY-FORMING UNIT (CFU);

BIOMATERIALS;

CHLORHEXIDINE ACETATE; POLY(ETHYL METHACRYLATE); POLYMER; TETRAHYDROFURFURYL METHACRYLATE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; COLONY FORMING UNIT; DRUG DELIVERY SYSTEM; DRUG RELEASE; FUNGUS GROWTH; NONHUMAN; PRIORITY JOURNAL; SAMPLE; SUSTAINED RELEASE FORMULATION; THRUSH; WATER TRANSPORT;

ADMINISTRATION, ORAL; ANTIFUNGAL AGENTS; BIOCOMPATIBLE MATERIALS; CANDIDA ALBICANS; CHLORHEXIDINE; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, FUNGAL; HUMANS; MATERIALS TESTING; METHACRYLATES; METHYLMETHACRYLATES; POLYMERS;

CANDIDA; CANDIDA ALBICANS;

EID: 0034911472     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(00)00367-7     Document Type: Article

References (38)

1. Oral candida infections - a review
2. Fungal infections of the oral cavity
3. Emergence of azole drug resistance in Candida species from HIV-infected patients receiving prolonged fluconazole therapy for oral candidosis
4. Stable azole drug resistance associated with a substrain of Candida albicans from an HIV-infected patient
5. Effects of tetracycline hyrochloride and chlorhexidine gluconate on Candida albicans
6. In vitro antifungal properties of mouthrinses containing antimicrobial agents
7. Effect of chlorhexidine diacetate on Candida albicans, C. glabrata, and Saccharomyces cerevisiae
8. Use of a microtitre plate assay to detect the rate of killing of adherent Candida albicans by antifungal agents
9. Oral Candida albicans in bone marrow transplant patients given chlorhexidine rinses; occurrences and susceptibilities to the agent
10. Heterocyclic methacrylates for clinical applications. II. Room temperature polymerising systems for potential clinical use
11. Polymerisation shrinkage of some methacrylate esters
12. Heterocyclic methacrylates for clinical applications. I. Mechanical properties
13. The effects of two temporary crown and bridge materials on the dental pulp of monkeys (Macaca fascularisi)
14. The regeneration of articular cartilage using a new polymer system
15. New methacrylate for use in orthopaedic surgery
16. Heterocyclic methacrylates for clinical applications. III: water absorption properties
17. Reduced azole susceptibility of oral isolates of Candida albicans from HIV-positive patients and a derivative exhibiting colony morphology variation
18. An in vitro and in vivo study of the effect of incorporation of chlorhexidine into autopolymerizing resin plates upon the growth of Candida albicans
19. Heterocyclic methacrylates for clinical applications - further studies of water sorption
20. Water absorption properties of polymeric systems based on tetrahydrofurfuryl methacrylate
21. The effect of two hydrophilic monomers on the water uptake of a heterocyclic methacrylate system
22. The water uptake of poly(tetrahydrofurfuryl methacrylate)
23. Drug release from acrylic polymers via channels and cracks; in vitro studies with hydrocortisone
24. Validation and optimization of a polymer system for potential use as a controlled drug delivery system
25. Heterocyclic methacrylates based drug release polymer systems
26. Effects of chlorhexidine diacetate on Candida albicans, C glabrata and Saccharomyces cerevisiae
27. Frequency and distribution of Candida albicans blastospores adhered to mucosal epithelial cells in vitro
28. New sustained release dosage form of chlorhexidine for dental use; use for plaque control in partial denture wearers
29. The effect of sustained release application of chlorhexidine on salivary levels of Streptococcus mutans in partial denture wearers
30. Local delivery of chlorhexidine using a tooth-bonded delivery system
31. In vitro studies into the use of denture base and soft liner materials as carriers for drugs in the mouth
32. In vitro studies into the release of chlorhexidine acetate, prednisolone sodium phosphate and prednisolone alcohol from cold cure denture acrylic
33. The release of chlorhexidine from modified dental acrylic resin
34. The effects of drug and water incorporation upon some physical properties of cold cured acrylic