Is hepatic cytochrome P4501A1 expression predictive of hepatic burdens of dioxins, furans, and PCBs in Atlantic tomcod from the Hudson River estuary?

Aquatic Toxicology

Volumn 54, Issue 3-4, 2001, Pages 217-230

  Yuan, Zhanpeng ^a   Wirgin, Michael ^a   Courtenay, Simon ^b   Ikonomou, Michael ^c   Wirgin, Isaac ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GULF FISHERIES CENTRE   (Canada)

^c INSTITUTE OF OCEAN SCIENCES   (Canada)

Author keywords

Biomarkers; Dioxins; Furans; Gene expression; Hudson River; PCBs

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 2,3,7,8 TETRACHLORODIBENZOFURAN; 3,3',4,4' TETRACHLOROBIPHENYL; 3,3',4,4',5,5' HEXACHLOROBIPHENYL; 3,4,4',5 TETRACHLOROBIPHENYL; BIOLOGICAL MARKER; CYTOCHROME P450 1A1; DIOXIN; FURAN DERIVATIVE; MESSENGER RNA; POLYCHLORINATED BIPHENYL; POLYCYCLIC AROMATIC HYDROCARBON; UNCLASSIFIED DRUG; XENOBIOTIC AGENT;

AROMATIC HYDROCARBON; BIOLOGICAL UPTAKE; BIOMARKER; ESTUARY;

ANIMAL TISSUE; AQUATIC FAUNA; ARTICLE; BIOAVAILABILITY; CONCENTRATION RESPONSE; CONTAMINATION; CONTROLLED STUDY; ECOSYSTEM; ESTUARY; FEMALE; FISH; GENE EXPRESSION; LIVER; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEDIMENT;

ANIMALS; BIOLOGICAL AVAILABILITY; BIOLOGICAL MARKERS; CYTOCHROME P-450 CYP1A1; DIOXINS; ENVIRONMENTAL EXPOSURE; FISHES; FURANS; GENE EXPRESSION REGULATION; LIVER; POLYCHLORINATED BIPHENYLS; WATER POLLUTANTS, CHEMICAL;

UNITED STATES;

MICROGADUS TOMCOD; PISCES;

EID: 0034910938     PISSN: 0166445X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-445X(01)00144-8     Document Type: Article

References (51)

1. Low inducibility of CYP1A activity by polychlorinated biphenyls (PCBs) in flounder (Platichthys flesus): Characterization of the Ah receptor and the role of CYP1A inhibition
2. A major incident of dioxin contamination: Sediments of New Jersey estuaries
3. Trends in chlorinated hydrocarbon levels in Hudson River basin sediments
4. Serum dioxin, chloracne, and acne in veterans of Operation Ranch Hand
5. The nucleotide sequence of a rat 18S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18S ribosomal ribonucleic acid
6. Induction and clearance of cytochrome P4501A mRNA in Atlantic tomcod caged in bleached kraft mill effluent in the Miramichi River
7. A comparison of the dose and time response of CYP1A1 mRNA induction in chemically treated Atlantic tomcod from two populations
8. Epizoology of hepatic neoplasia in Atlantic tomcod (Microgadus tomcod) from the Hudson River estuary
9. Comparative toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin to seven freshwater fish species during early-life development
10. Altered CYP1A expression in Fundulus heteroclitus adults and larvae - A sign of pollutant resistance?
11. Reference method for the determination of polychlorinated dibenzo-para-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in pulp and paper mill effluents
12. Internal quality assurance requirements for the analysis of dioxins in environment samples
13. Fate and bioaccumulation of PCBs in aquatic environments
14. Distribution of heavy metal and PCB contaminants in the sediments of an urban estuary: The Hudson River
15. Northern blotting: Efficient staining and transfer
16. Mechanisms of innate and acquired resistance to dioxin-like compounds. Reviews in Toxicology
17. Distribution of polycyclic aromatic hydrocarbon (PAHs) in three northern New Jersey waterways
18. DNA methylation and gene expression: Introduction and overview
19. Life history of Atlantic tomcod, Microgadus tomcod, in the Hudson River estuary, with emphasis on spatio-temporal distribution and movements
20. Associations between metabolites of aromatic compounds in bile and the occurrence of hepatic lesions in the English sole (Parophrys vetulus) from Puget Sound, Washington
21. Determination of individual metabolites of aromatic compounds in hydrolized bile of English sole (Parophrys vetulus) from polluted sites in Puget Sound, Washington
22. Cytochrome P450IA mRNA expression in feral Hudson River tomcod
23. 2,3,7,8-tetrachlorodibenzo-p-dioxin plasma levels in Seveso 20 years after the accident
24. 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteosome pathway
25. Contaminants in white sturgeon (Acipenser transmontanus) from the Upper Fraser River, British Columbia
26. Adaptations of wild populations of the estuarine fish Fundulus heteroclitus to persistent environmental contaminants
27. The aryl-hydrocarbon receptor, but not the aryl-hydrocarbon receptor nuclear translocator protein, is rapidly depleted in hepatic and nonhepatic culture cells exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin
28. Female Sprague-Dawley rats exposed to a single oral dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibit sustained depletion of aryl hydrocarbon receptor protein in liver, spleen, thymus, and lung
29. Comparisons of the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on chemically impacted and nonimpacted subpopulations of Fundulus heteroclitus. II. Metabolic considerations
30. Characterization of the aromatic hydrocarbon receptor gene and its expression in Atlantic tomcod
31. Characterization and prevalence of a polymorphism in the 3' untranslated region of cytochrome P4501A1 in cancer-prone Atlantic tomcod
32. An evaluation of the etiology of reduced CYP1A1 mRNA expression in Atlantic tomcod from the Hudson River using RT-PCR analysis
33. The potential role of DNA methylation in the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin
34. Biochemistry and molecular biology of monooxygenases: Current perspectives on forms, functions, and regulation of cytochrome P450 in aquatic species
35. Molecular epizootiology: Assessment of exposure to genotoxic compounds in teleosts
36. Induction of CYP1A1 gene expression in mouse hepatoma cells by benzo[e]pyrene, a ligand of the 4S polycyclic hydrocarbon-binding protein
37. Disposition of xenobiotic chemicals and metabolites in marine organisms
38. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife
39. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) toxicity during early life stage development of lake trout (Salvelinus namaycush)
40. Accumulation of metals, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons in sediments from the lower Passaic River, New Jersey
41. Annual sex steroid profiles and effects of gender and season on cytochrome P450 mRNA induction in Atlantic tomcod (Microgadus tomcod)
42. Effects of prior exposure history on cytochrome P450IA mRNA induction by PCB congener 77 in Atlantic tomcod
43. A biomarker approach in assessing xenobiotic exposure in cancer-prone Atlantic tomcod from the North American Atlantic coast
44. A comparison of cytochrome P4501A (CYP1A) mRNA inducibility in four species of Atlantic coast anadromous fishes
45. Embryotoxicity of Great Lakes lake trout extracts to developing rainbow trout