NF-1C, Sp1, and Sp3 are essential for transcription of the human gene for P450c17 (steroid 17α-hydroxylase/17,20 lyase) in human adrenal NCI-H295A cells

Molecular Endocrinology

Volumn 15, Issue 8, 2001, Pages 1277-1293

  Lin, Chin Jia ^a   Martens, John W M ^a   Miller, Walter L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; NUCLEAR FACTOR I; STEROID 17,20 LYASE; STEROID 17ALPHA MONOOXYGENASE; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3;

ADRENAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; DELETION MUTANT; DNA FLANKING REGION; DNA FOOTPRINTING; ENZYME ACTIVITY; GENE SEQUENCE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; METHYLATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION;

ADRENAL GLAND NEOPLASMS; ADRENAL GLANDS; ANIMALS; BASE SEQUENCE; BINDING SITES; CELL LINE; CONSERVED SEQUENCE; COS CELLS; DEOXYRIBONUCLEASE I; DNA; DNA FOOTPRINTING; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; LIVER NEOPLASMS; MICE; MUTAGENESIS, SITE-DIRECTED; NFI TRANSCRIPTION FACTORS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); SEQUENCE ANALYSIS, DNA; SP1 TRANSCRIPTION FACTOR; SP3 TRANSCRIPTION FACTOR; STEROID 17-ALPHA-HYDROXYLASE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0034909430     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.15.8.1277     Document Type: Article

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