On genetic and phenotypic variability of hypertrophic cardiomyopathy: Nature versus nurture

Journal of the American College of Cardiology

Volumn 38, Issue 2, 2001, Pages 331-334

  Marian, Ali J ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b Section of Cardiology   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MYOSIN BINDING PROTEIN C;

AGE; EDITORIAL; ENVIRONMENTAL FACTOR; GENE MUTATION; GENETIC VARIABILITY; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; MOLECULAR BIOLOGY; PATHOGENESIS; PHENOTYPE; POPULATION RESEARCH; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; RISK ASSESSMENT;

CARDIOMYOPATHY, HYPERTROPHIC; CARRIER PROTEINS; ENVIRONMENT; HUMANS; MUTATION; PHENOTYPE; VARIATION (GENETICS);

EID: 0034908293     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0735-1097(01)01389-4     Document Type: Editorial

References (19)

1. A molecular basis for familial hypertrophic cardiomyopathy: A beta-cardiac myosin heavy chain gene missense mutation
2. The molecular genetic basis for hypertrophic cardiomyopathy
3. Alpha-tropomyosin and cardiac troponin-T mutations cause familial hypertrophic cardiomyopathy: A disease of the sarcomere
4. Cardiac myosin binding protein-C gene splice acceptor site mutation is associated with familial hypertrophic cardiomyopathy
5. Mutations in the gene for cardiac myosin-binding protein C and late-onset familial hypertrophic cardiomyopathy
6. Clinical features and prognostic implications of familial hypertrophic cardiomyopathy related to the cardiac myosin-binding protein C gene
7. Mutations in the cardiac myosin binding protein-C gene on chromosome 11 cause familial hypertrophic cardiomyopathy
8. Prognostic significance of beta-myosin heavy chain mutations is reflective of their hypertrophic expressivity in patients with hypertrophic cardiomyopathy
9. Mutations in the genes for cardiac troponin T and alpha-tropomyosin in hypertrophic cardiomyopathy
10. Spectrum of clinical phenotypes and gene variants in cardiac myosin-binding protein C mutation carriers with hypertrophic cardiomyopathy
11. Development of left ventricular hypertrophy in adults with hypertrophic cardiomyopathy caused by cardiac myosin-binding protein C gene mutations
12. Organization and sequence of human cardiac myosin binding protein C gene (MYBPC3) and identification of mutations predicted to produce truncated proteins in familial, hypertrophic cardiomyopathy
13. Pathogenesis of diverse clinical and pathological phenotypes in hypertrophic cardiomyopathy
14. A transgenic rabbit model for human hypertrophic cardiomyopathy
15. Tissue Doppler imaging consistently detects myocardial contraction and relaxation abnormalities, irrespective of cardiac hypertrophy, in a transgenic rabbit model of human hypertrophic cardiomyopathy
16. Angiotensin-converting enzyme polymorphism in hypertrophic cardiomyopathy and sudden cardiac death
17. Angiotensin-converting enzyme genotypes and left ventricular hypertrophy in patients with hypertrophic cardiomyopathy
18. The influence of the angiotensin-1-converting enzyme genotype in familial hypertrophic cardiomyopathy varies with the disease gene mutation
19. Cardiac myosin binding protein C