Is glutathione-S-transferase-π expression a reliable predictor of chemoradiation response in cancer of the head and neck?

American Journal of Otolaryngology - Head and Neck Medicine and Surgery

Volumn 22, Issue 4, 2001, Pages 257-260

  Vural, Emre ^a   Alexiou, Michael ^a   Hunt II, Justin ^a   Korourian, Soheila ^a   Hanna, Ehab ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FLUOROURACIL; GLUTATHIONE TRANSFERASE; POLYCLONAL ANTIBODY;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER SURVIVAL; CLINICAL ARTICLE; CORRELATION FUNCTION; FEMALE; HEAD AND NECK CANCER; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; PREDICTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RELIABILITY; SCORING SYSTEM; SQUAMOUS CELL CARCINOMA; TUMOR BIOPSY;

EID: 0034903995     PISSN: 01960709     EISSN: None     Source Type: Journal    
DOI: 10.1053/ajot.2001.24824     Document Type: Article

References (11)

1. Aggressive concurrent chemoradiotherapy for squamous cell head and neck cancer. An 8-year single-institution experience
2. Expression of glutathione S-transferase-π in human ovarian cancer as an indicator of resistance in chemotherapy
3. Immunohistochemical expression of glutathione S-transferase-π can predict chemotherapy response in patients with non-small cell lung carcinoma
4. Glutathione S-transferases and glutathione in human head and neck cancer
5. Role of glutathione s-transferases and multidrug resistance-related proteins in cisplatin sensitivity of head and neck cancer cell lines
6. Overexpression and amplification of glutathione S-transferase π gene in head and neck squamous cell carcinomas
7. Association between expression of glutathione-associated enzymes and response to platinum-based chemotherapy in head and neck cancer
8. Relationship of glutathione and glutathione s-transferase to cisplatin sensitivity in human head and neck squamous carcinoma cell lines
9. Chemosensitivity of head and neck squamous carcinoma cell lines is not primarily correlated with glutathione level but is modified by glutathione depletion
10. Immunohistochemical staining for glutathione s-transferase predicts response to platinum-based chemotherapy in head and neck cancer
11. Expression of glutathione s-transferase π in human squamous cell carcinomas of the pharynx and larynx. Loss after radiation therapy