Morpholino-induced knockdown of fgf8 efficiently phenocopies the acerebellar (ace) phenotype

Genesis (United States)

Volumn 30, Issue 3, 2001, Pages 157-159

  Araki, Isato ^a   Brand, Michael ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE;

ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CONTROLLED STUDY; EMBRYO; HEART DEVELOPMENT; IN SITU HYBRIDIZATION; KNOCKOUT GENE; NONHUMAN; OPTIC CHIASM; PHENOTYPE; PRIORITY JOURNAL; TELENCEPHALON;

ANIMALIA;

EID: 0034898145     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.1054     Document Type: Article

References (8)

1. Mutations in zebrafish genes affecting the formation of the boundary between midbrain and hindbrain
2. A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary
3. Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection
4. Tight transcriptional control of the ETS domain factors Erm and Pea3 by fgf signaling during early zebrafish nervous system development
5. Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis
6. Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar)
7. Overlapping and distinct functions provided by fgf17, a new zebrafish member of the fgf8/17/18 subgroup of fgfs
8. Ace/fgf8 is required for forebrain commissure formation and patterning of the telencephalon