Calcium binding to an elastic portion of connectin/titin filaments

Journal of Muscle Research and Cell Motility

Volumn 22, Issue 2, 2001, Pages 149-162

  Tatsumi, R ^a   Maeda, K ^a   Hattori, A ^a   Takahashi, K ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIN;

ACTIN FILAMENT; AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM BINDING; CONTROLLED STUDY; DNA SEQUENCE; ELASTICITY; EXCITATION CONTRACTION COUPLING; MUSCLE CONTRACTION; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; SARCOMERE LENGTH;

ANIMALS; BINDING SITES; CALCIUM; CALCIUM CHLORIDE; CALCIUM SIGNALING; CHICKENS; ELASTICITY; IMMUNOHISTOCHEMISTRY; MICROSCOPY, ELECTRON; MOLECULAR WEIGHT; MUSCLE CONTRACTION; MUSCLE FIBERS; MUSCLE PROTEINS; MUSCLE, SKELETAL; PROTEIN KINASES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RABBITS; SWINE;

ANIMALIA;

EID: 0034897730     PISSN: 01424319     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010349416723     Document Type: Article

References (86)

1. A Drosophila photoreceptor cell-specific protein, calphotin, binds calcium and contains a leucine zipper
2. Intracellular calcium accumulation in Duchenne dystrophy and other myopathies: A study of 567,000 muscle fibers in 114 biopsies
3. Detection of antigens on nitrocellulose paper immunoblots with monoclonal antibodies
4. Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane
5. Interaction of paratropomyosin with β-connectin and its 400-kiloDalton fragment from chicken skeletal muscle as influenced by the calcium ion concentration
6. Partial titin cDNA sequence isolated from rabbit cardiac muscle RNA
7. Titin, a huge, elastic sarcomeric protein with a probable role in morphogenesis
8. Elastic filaments in skeletal muscle revealed by selective removal of thin filaments with plasma gelsolin
9. Elastic filaments in situ in cardiac muscle: Deep-etch replica analysis in combination with selective removal of actin and myosin filaments
10. The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: A map of ten nonrepetitive epitopes starting at the Z line extends close to the M line
11. Repetitive titin epitopes with a 42 nm spacing coincide in relative position with known A band striations also identified by major myosin-associated proteins: An immunoelectron-microscopical study on myofibrils
12. Phosphorylation of KSP motifs in the C-terminal region of titin in differentiating myoblasts
13. A molecular map of titin/connectin elasticity reveals two different mechanisms acting in series
14. The central Z-disk region of titin is assembled from a novel repeat in variable copy numbers
15. Nonuniform elasticity of titin in cardiac myocytes: A study using immunoelectron microscopy and cellular mechanics
16. Localization of paratropomyosin in skeletal muscle myofibrils and its translocation during postmortem storage of muscles
17. A physiological role for titin and nebulin in skeletal muscle
18. The positional stability of thick filaments in activated skeletal muscle depends on sarcomere length: Evidence for the role of titin filaments
19. Elastic behavior of connectin filaments during thick filament movement in activated skeletal muscle
20. Sodium dodecyl sulfate gel electrophoresis studies of connectin-like high molecular weight proteins of various types of vertebrate and invertebrate muscles
21. The calcium binding sites in human annexin V by crystal structure analysis at 2.0 Å resolution: Implications for membrane binding and calcium channel activity
22. Native connectin from porcine cardiac muscle
23. Extensible and less-extensible domains of connectin filaments in stretched vertebrate skeletal muscle sarcomeres as detected by immunofluorescence and immunoelectron microscopy using monoclonal antibodies
24. Cloned rat cardiac titin class I and class II motifs: Expression, purification, characterization, and interaction with F-actin
25. Localization of three fragments of connectin in chicken breast muscle sarcomeres
26. Determination of the free-energy coupling for binding of calcium ions and troponin I to calmodulin
27. Folding-unfolding transitions in single titin molecules characterized with laser tweezers
28. Preparation of native connectin from chicken breast muscle
29. Proteolytic fragments of connectin cause aggregation of myosin filaments but not of actin filaments
30. Isolation of α-connectin, an elastic protein, from rabbit skeletal muscle
31. Characterization and localization of α-connectin (titin 1): An elastic protein isolated from rabbit skeletal muscle
32. The role of a thiol protease in the proteolysis of connectin in rabbit skeletal muscle myofibrils
33. A systematic search of the data bases for sequences homologous to titin/connectin
34. Carp muscle calcium-binding protein
35. A regular pattern of two types of 100-residue motif in the sequence of titin
36. Towards a molecular understanding of titin
37. Titins: Giant proteins in charge of muscle ultrastructure and elasticity
38. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
39. The effect of genetically expressed cardiac titin fragments on in vitro actin motility
40. Towards a molecular understanding of the elasticity of titin
41. A comparative study of high molecular weight proteins in various types of muscle across the animal kingdom
42. Calphotin: A Drosophila photoreceptor cell calcium-binding protein
43. Connectin, an elastic filamentous protein of striated muscle
44. Connectin, an elastic protein of striated muscle
45. Connectin/titin, giant elastic protein of muscle
46. Molecular size and shape of beta-connectin, an elastic protein of striated muscle
47. Connectin filaments link thick filaments and Z-lines in frog skeletal muscle as revealed by immunoelectron microscopy
48. Circular dichroism spectra show abundance of β-sheet structure in connectin, a muscle elastic protein
49. The L-2 light chain of chicken skeletal muscle myosin
50. Isolation and characterization of 1200 kDa peptide of α-connectin
51. Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores
52. The role of myofibrils, sarcoplasma and sarcolemma in muscle contraction
53. Chicken leg muscle α-connectin as studied by a monoclonal antibody to the 1200 kDa fragment
54. Calcium binding to complexes of calmodulin and calmodulin binding proteins
55. Filament lengths in striated muscle
56. A study of the effects of substrate concentration and certain relaxing factors on the magnesium-activated myofibrillar adenosine triphosphatase
57. The organization of titin (connectin) and nebulin in the sarcomeres: An immunocytolocalization study
58. The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase
59. Estimation of globular protein secondary structure from circular dichroism
60. Reversible unfolding of individual titin immunoglobulin domains by AFM
61. Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence
62. Structure and physiological functions of ubiquitous and tissue-specific calpain species: Muscle-specific calpains, p94, interacts with connectins/titin
63. Electron microscopic filament lengths of connectin and its fragments
64. Proteolytic cleavage of connectin/titin
65. Non-enzymatic weakening of myofibrillar structures during conditioning of meat: Calcium ions at 0.1 mM and their effect on meat tenderization
66. Structural weakening of skeletal muscle tissue during postmortem ageing of meat: The non-enzymatic mechanism of meat tenderization
67. Calcium-induced splitting of connectin filaments into β-connectin and a 1200-kDa subfragment
68. Purification and characterization of the 1200-kDa subfragment of connectin filaments produced by 0.1 mM calcium ions
69. 2
70. Detection of giant myofibrillar proteins connectin and nebulin by electrophoresis in 2% polyacrylamide slab gels strengthened with agarose
71. Splitting of connectin (titin) filaments into β-connectin (T2) and a 1200-kDa subfragment by 0.1 mM calcium ions
72. Fluorescence detection of calcium-binding proteins with quinoline Ca-indicator quin2
73. Deterioration of connectin/titin and nebulin filaments by an excess of Protease inhibitors
74. Interaction of titin/connectin with the thick filament
75. The mechanically active domain of titin in cardiac muscle
76. Titin extensibility in situ: Entropic elasticity of permanently folded and permanently unfolded molecular segments
77. PEVK extension of human soleus muscle titin revealed by immunolabeling with anti-titin antibody 9D10
78. Calcium homeostasis in intact lymphocytes: Cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator
79. Elasticity and unfolding of single molecules of the giant muscle protein titin
80. Sarcomere-associated cytoskeletal lattices in striated muscle: Review and hypothesis
81. Immunocytochemical studies using a monoclonal antibody to bovine cardiac titin on intact and extracted myofibrils
82. Does titin regulate the length of muscle thick filaments?
83. Binding of paratropomyosin to β-connectin from chicken skeletal muscle
84. Mutations in calphotin, the gene encoding a Drosophila photoreceptor cell-specific calcium-binding protein, reveal roles in cellular morphogenesis, survival
85. 2+
86. Changes in the molecular size of connectin, an elastic protein, in chicken skeletal muscle during embryonic and neonatal development