Repression of fatty-acyl-CoA oxidase-encoding gene expression is not necessarily a determinant of high-level production of dicarboxylic acids in industrial dicarboxylic-acid-producing Candida tropicalis

Applied Microbiology and Biotechnology

Volumn 56, Issue 3-4, 2001, Pages 478-485

  Hara, A ^a   Ueda, M ^b   Matsui, T ^a   Arie, M ^a   Saeki, H ^a   Matsuda, H ^a   Furuhashi, K ^a   Kanai, T ^b   Tanaka, A ^b  

^a JAPAN ENERGY CORPORATION   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A DEHYDROGENASE; DICARBOXYLIC ACID;

BIOTECHNOLOGY;

ARTICLE; CANDIDA TROPICALIS; ENZYME ACTIVITY; FUNGUS MUTANT; GENE EXPRESSION REGULATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; SEQUENCE ANALYSIS; SOUTHERN BLOTTING; SYNTHESIS;

ACYL-COA OXIDASE; AMINO ACID SEQUENCE; BASE SEQUENCE; CANDIDA; CLONING, MOLECULAR; DICARBOXYLIC ACIDS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES; PLASMIDS; SEQUENCE ANALYSIS, DNA;

EID: 0034893228     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002530000543     Document Type: Article

References (27)

1. Characterization of a dicarboxylic acid-producing mutant of the yeast Candida tropicalis
2. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
3. Development of an integrative DNA transformation system for the yeast Candida tropicalis
4. Construction of an autonomously replicating plasmid in n-alkane-assimilating yeast, Candida tropicalis
5. Mutated hygromycin resistance gene is functional for the n-alkane-assimilating yeast, Candida tropicalis
6. The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae
7. Genetic evaluation of physiological functions of thiolase isozymes in n-alkane-assimilating yeast, Candida tropicalis
8. A complex containing two transcription factors regulates peroxisome proliferation and the coordinate induction of β-oxidation enzymes in Saccharomyces cerevisiae
9. β-Galactosidase of Kluyveromyces lactis (Lac4p) as reporter of gene expression in Candida albicans and C. Tropicalis
10. Expression of an endogenous and a heterologous gene in Candida maltosa by using a promoter of a newly-isolated phosphoglycerate kinase (PGK)
11. Cloning and characterization of the POX2 gene in Candida maltosa
12. Isozyme function of n-alkane-inducible cytochromes P450 in Candida maltosa revealed by sequential gene disruption
13. Two acyl-coenzyme A oxidase in peroxisomes of the yeast Candida tropicalis: Primary structures deduced from genomic DNA sequence
14. Peroxisomal acyl-coenzyme A oxidase multigene family of the yeast Candida tropicalis; nucleotide sequence of a third gene and its protein product
15. Ultrastructure of Candida yeasts grown on n-alkanes
16. Determination of Candida tropicalis acyl coenzyme A oxidase isozyme function by sequential gene disruption
17. Metabolic engineering of Candida tropicalis for the production of long-chain dicarboxylic acid
18. Targeted integrative transformation of Candida tropicalis by electroporation
19. Pip2p: A transcriptional regulator of peroxisome proliferation in the yeast Saccharomyces cerevisiae
20. A heterodimer of the Zn2Cys6 transcription factors Pip2p and Oaf1p controls induction of genes encoding peroxisomal proteins in Saccharomyces cerevisiae
21. Disruption of the gene encoding the acyl-CoA-binding protein (ACB1) perturbs acyl-CoA metabolism in Saccharomyces cerevisiae
22. Acyl-CoA oxidase from Candida tropicalis
23. Assimilation of alkanes by yeasts - Functions and biogenesis of peroxisomes
24. Industrialization of production of dicarboxylic acid from n-paraffins
25. Disruption of the Saccharomyces cerevisiae FAT1 gene decreases very long-chain fatty acyl-CoA synthetase activity and elevates intracellular very long-chain fatty acid concentrations