Screening of environmental contaminants for ecdysteroid agonist and antagonist activity using the Drosophila Melanogaster BII cell in vitro assay

Environmental Toxicology and Chemistry

Volumn 20, Issue 9, 2001, Pages 2038-2046

  Dinan, L ^a   Bourne, P ^a   Whiting, P ^a   Dhadialla, T S ^a   Hutchinson, T H ^a  

^a UNIVERSITY OF EXETER   (United Kingdom)

Author keywords

Disrupter; Ecdysteroid; Endocrine; Invertebrate; Steroid receptor

Indexed keywords

BIOASSAY; CELLS; DRUG PRODUCTS; IMPURITIES; INDUSTRIAL CHEMICALS; PESTICIDES; SCREENING;

CELL LINES;

WEATHERING;

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; 4,4' ISOPROPYLIDENEDIPHENOL; DIELDRIN; ECDYSTEROID; ETHINYLESTRADIOL; STEROID RECEPTOR;

POLLUTANT;

ARTHROPOD; ARTICLE; BINDING SITE; BIOASSAY; CRUSTACEA; DROSOPHILA MELANOGASTER; ENDOCRINE SYSTEM; INSECT; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; WATER POLLUTION;

ANIMALS; BIOLOGICAL ASSAY; CELL LINE; CRUSTACEA; DROSOPHILA MELANOGASTER; ECDYSTEROIDS; ENVIRONMENTAL MONITORING; INSECTS; MOLTING; WATER POLLUTANTS, CHEMICAL; XENOBIOTICS;

ANIMALIA; ARTHROPODA; CRUSTACEA; DROSOPHILA MELANOGASTER; FORMICIDAE; HEXAPODA; INSECTA; INVERTEBRATA; MELANOGASTER; VERTEBRATA;

EID: 0034887565     PISSN: 07307268     EISSN: None     Source Type: Journal    
DOI: 10.1002/etc.5620200924     Document Type: Article

References (36)

1. Endocrine function in aquatic invertebrates and evidence for disruption by environmental pollutants
2. Daphnia magna reproduction test
3. Guideline on chironomid toxicity test using spiked water and a draft new guideline on chironomid toxicity testing using spiked sediment
4. Physiological and biochemical perturbations in Daphnia magna following exposure to the model environmental estrogen diethylstilbestrol
5. Life-cycle studies with marine copepods (Tisbe battagliai) exposed to 20-hydroxyecdysone and diethylstilboestrol
6. The effect of phthalate ester plasticisers on the emergence of the midge Chironomus riparius from treated sediments
7. Laboratory toxicity tests for evaluating potential effects of endocrine disrupting compounds
8. Intersexuality in benthic harpacticoid copepods in the Firth of Forth, Scotland
9. Critical appraisal of the evidence for tributyltin-mediated endocrine disruption in mollusks
10. Health effects of endocrine disrupting chemicals on wildlife, with special reference to the European situation
11. Impact of ecdysteroids and oestrogens on developmental and reproductive parameters in the marine copepod Tisbe battagliai
12. Functional ecdysone receptor is the product of EcR and Ultraspiracle genes
13. Development of an assay for ecdysteroid-like and anti-ecdysteroid activities in plants
14. Assessment of a microplate-based bioassay for the detection of ecdysteroid-like or antiecdysteroid activities
15. Plant natural products as insect steroid receptor agonists and antagonists
16. A strategy for the identification of ecdysteroid receptor agonists and antagonists from plants
17. Identification and ecdysteroid antagonist activity of three resveratrol trimers (suffruticosols A, B and C) from Paeonia suffruticosa
18. An extensive ecdysteroid CoMFA
19. Ecdysteroid receptors in a tumorous blood cell line of Drosophila melanogaster
20. II cell line
21. Cucurbitacins are insect steroid hormone antagonists acting at the ecdysteroid receptor
22. Juvenoids and anti-juvenile hormone agents: Past and present
23. Cyromazine - An insecticide that affects the cuticle
24. Structure-activity study and conformational analysis of RH-5992, the first commercialized nonsteroidal ecdysone agonist
25. A review of the environmental fate, effects, and exposures of bisphenol A
26. Lindane
27. Measurement of water solubilities, octanol/water partition coefficients and vapor pressures of commercial phthalate esters
28. Diethyl phthalate
29. Metabolism and environmental degradation of pyrethroid insecticides produce compounds with endocrine activities
30. Effects of estrogenic xenobiotics on molting of the water flea, Daphnia magna
31. Effects of exposure to diethy lphthalate, 4-(tert)-octylphenol, and 2, 4, 5-trichlorobiphenyl on the activity of chitobioase in the epidermis and hepatopancreas of the fiddler crab, Uca pugilator
32. No estrogenic effects of bisphenol A in Daphnia magna Straus