Inhibition of neurite extension by overexpression of individual domains of LIM kinase 1

Journal of Neurochemistry

Volumn 78, Issue 4, 2001, Pages 924-927

  Birkenfeld, Jörg ^a   Betz, Heinrich ^a   Roth, Dagmar ^a  

^a MAX PLANCK INSTITUTE FOR BRAIN RESEARCH   (Germany)

Author keywords

Actin; Cofilin; Neurite outgrowth; PC12 cells

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN DEPOLYMERIZING FACTOR; COFILIN; LIM PROTEIN; NERVE GROWTH FACTOR; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; NEURITE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

AMIDES; ANIMALS; CELL LINE; CELL SIZE; ENZYME INHIBITORS; GENES, REPORTER; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICE; NERVE GROWTH FACTOR; NEURITES; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; PYRIDINES; RATS; RECOMBINANT FUSION PROTEINS; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0034887416     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00500.x     Document Type: Article

References (27)

1. Phosphorylation of cofilin by LIM-kinase is nescessary for semaphorin 3A-induced growth cone collapse
2. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
3. Proteins of the ADF/cofilin family: Essential regulators of actin dynamics
4. Kiz-1, a protein with LIM zinc fingers and kinase domains, is expressed mainly in neurons
5. Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion
6. Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
7. Structural features of LIM kinase that control effects on the actin cytoskeleton
8. LIM-kinase 1 hemizygosity implicated in impaired visuospatial constructive cognition
9. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
10. Inhibition of activated Ras-induced neuronal differentiation of PC12 cells by the LIM domain of LIM-kinase 1
11. Self-association of LIM-kinase 1 mediated by the interaction between an N-terminal LIM domain and a C-terminal kinase domain
12. Molecular dissection of the Rho-associated protein kinase (p160ROCK)-regulated neurite remodeling of neuroblastoma N1E-115 cells
13. Pharmacological properties of Y-27632, a specific inhibitor of Rho-associated kinases
14. Regulating actin dynamics in neuronal growth cones by ADF/cofilin and rho family GTPases
15. Protein-protein interaction of zinc finger LIM domains with protein kinase C
16. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
17. Actin depolymerizing factor and cofilin phosphorylation dynamics: Response to signals that regulate neurite extension
18. The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1
19. LIMK-1 and LIMK-2, two members of a LIM motif-containing protein kinase family
20. Rho-associated kinase ROCK activates LIM-kinase 1 by phosphorylation at threonine 508 within the activation loop
21. Identification and characterization of TESK2, a novel member of the LIMK/TESK family of protein kinases, predominantly expressed in testis
22. LIM-kinase 1
23. Making the connection: Cytoskeletal rearrangements during growth cone guidance
24. Identification and characterization of a novel protein kinase, TESKI, specifically expressed in testicular germ cells
25. Transmembrane neuregulins interact with LIM Kinase 1, a cytoplasmic protein kinase implicated in development of visuospatial cognition
26. Cytoplasmic localization of LIM-Kinase 1 is directed by a short sequence within the PDZ domain
27. Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization