Protein oxidation and ageing

Experimental Gerontology

Volumn 36, Issue 9, 2001, Pages 1503-1518

  Linton, Stuart ^a   Davies, Michael J ^a   Dean, Roger T ^a  

^a HEART RESEARCH INSTITUTE   (Australia)

Author keywords

Ageing; Oxidative stress; Protein oxidation; Radicals; Reactive oxygen species

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE PEROXIDASE; PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

AGING; ARTICLE; HOMEOSTASIS; HUMAN; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN MODIFICATION;

AGING; ANIMALS; HUMANS; OXIDATION-REDUCTION; PROTEINS;

EID: 0034886774     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(01)00136-X     Document Type: Article

References (54)

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3. Oxidative DNA damage and senescence of human diploid fibroblast cells
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7. Molecular determinants of protein half-lives in eukaryotic cells
8. Oxidation of glycated proteins: age-dependent accumulation of N-epsilon-(carboxymethyl)lysine in lens proteins
9. Age-dependent accumulation of N-epsilon-(carboxymethyl)lysine and N-epsilon-(carboxymethyl)hydroxylysine in human skin collagen
10. Accumulation of Maillard reaction products in skin collagen in diabetes and aging
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12. ε-(carboxymethyl)lysine, is a product of both lipid peroxidation and glycoxidation reactions
13. The hydroxyl radical in lens nuclear cataractogenesis
14. Inactivation of key metabolic enzymes by mixed-function oxidation reactions: possible implication in protein turnover and ageing
15. Role of site-specific, metal-catalyzed oxidation in lens aging and cataract: a hypothesis
16. Selective oxidation of cysteine and methionine in normal and senile cataractous lenses
17. Detection of inactive enzyme molecules in ageing organisms
18. The aging process
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20. Generation and propagation of radical reactions on proteins
21. Human neutrophils employ myeloperoxidase to convert alpha-amino acids to a battery of reactive aldehydes: a pathway for aldehyde generation at sites of inflammation
22. Effect of diabetes and aging on carboxymethyllysine levels in human urine
23. Caloric restriction attenuates dityrosine cross-linking of cardiac and skeletal muscle proteins in aging mice
24. Markers of protein oxidation by hydroxyl radical and reactive nitrogen species in tissues of aging rats
25. Involvement of the proteasome in various degradative processes in mammalian cells
26. Methionine sulfoxide reductase in antioxidant defense
27. Age-related changes in oxidized proteins
28. Eukaryotic protein disulfide isomerase complements Escherichia coli dsbA mutants and increases the yield of a heterologous secreted protein with disulfide bonds
29. Glutamic and aminoadipic semialdehydes are the main carbonyl products of metal-catalyzed oxidation of proteins
30. Diquat-induced oxidative damage in BCNU-pretreated hepatocytes of mature and old rats
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45. Age-related accumulation of maillard reaction products in human articular cartilage collagen
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47. Catalysis of oxidative protein folding by mutants of protein disulfide isomerase with a single active-site cysteine
48. Oxidized amino acids in lens protein with age. Measurement of o-tyrosine and dityrosine in the aging human lens
49. Age-dependent increase in ortho-tyrosine and methionine sulfoxide in human skin collagen is not accelerated in diabetes. Evidence against a generalized increase in oxidative stress in diabetes