Focal adhesion kinase signaling is decreased in polyamine-depleted IEC-6 cells

American Journal of Physiology - Cell Physiology

Volumn 281, Issue 2 50-2, 2001, Pages

  Ray, Ramesh M ^a   Viar, Mary Jane ^a   Mccormack, Shirley A ^a   Johnson, Leonard R ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Attachment; Cell spreading; DL difluoromethylornithine; Focal adhesions; Integrins; Migration; Ornithine decarboxylase; Paxillin

Indexed keywords

EFLORNITHINE; F ACTIN; FOCAL ADHESION KINASE; INTEGRIN; ORNITHINE DECARBOXYLASE; PAXILLIN; POLYAMINE;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL ADHESION; CELL MIGRATION; CELL SPREADING; CYTOSKELETON; EXTRACELLULAR MATRIX; IMMUNOCYTOCHEMISTRY; INTESTINE MUCOSA; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0034885588     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2001.281.2.c475     Document Type: Article

References (30)

1. Stabilization of erythrocyte membranes by polyamines
2. A rapid and sensitive method for the quantitation of microgram amounts of protein utilizing the principle of protein-dye binding
3. Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: A role in cytoskeletal assembly
4. Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: A role for src family kinase
5. Requirements for restitution of the surface epithelium of frog stomach after mucosal injury
6. Modulation of cell proliferation and differentiation through substrate-dependent changes in fibronectin conformation
7. Integrin signaling
8. Inhibition of focal adhesion kinase (FAK) signaling in focal adhesions decreases cell motility and proliferation
9. Role of focal adhesion kinase in integrin in signaling
10. Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein
11. Polyamine deficiency alters EGF receptor distribution and signaling effectiveness in IEC- 6 cells
12. Polyamine depletion alters the relationship of F-actin, G-actin, and thymosin β4 in migrating IEC-6 cells
13. Polyamines are necessary for cell migration by a small intestinal crypt cell line
14. Polyamine deficiency causes reorganization of F-actin and tropomyosin in IEC-6 cells
15. Epithelioid cell cultures from rat small intestine
16. Polyamine depletion delays apoptosis of rat intestinal epithelial cells
17. Inhibition of cell spreading by expression of the C-terminal domain of focal adhesion kinase (FAK) is rescued by coexpression of src or catalytically inactive FAK: A role for paxillin tyrosine phosphorylation
18. Morphology and electrophysiology of guinea pig gastric mucosal repair in vitro
19. Polyamines are important for attachment of IEC-6 cells to extracellular matrix
20. pp125FAK, a structurally distinctive protein tyrosine kinase associated with focal adhesions
21. Fibronectinstimulated signaling from a focal adhesion kinase-c-src complex: Involvement of the Grb-2, p130 cas, and Nck adaptor proteins
22. Gastric mucosal defense and repair
23. Mechanism for rapid epithelialization of the gastric mucosal surface
24. 3-integrins
25. The role of focal adhesion kinase in the regulation of tyrosine phosphorylation of paxillin
26. Tyrosine phosphorylation of the focal adhesion pp125FAK during development: Relation to paxillin
27. Polyamines and ornithine decarboxylase during repair of duodenal mucosa after stress in rats
28. Role of ornithine decarboxylase in repair of gastric mucosal stress ulcers
29. Role of nonmuscle myosin II in polyamine-dependent intestinal epithelial cell migration
30. Differential regulation of pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion