Reduction of postsurgical adhesions with intergel® adhesion prevention solution: A multicenter study of safety and efficacy after conservative gynecologic surgery

Fertility and Sterility

Volumn 76, Issue 3, 2001, Pages 595-604

  Johns, Douglas B ^a   Keyport, Georgiann M ^b   Hoehler, Fred ^c   DiZerega, Gere S ^d  

^a ETHICON INC   (United States)

^b Lifecore Biomedical   (United States)

^c Statistics and Information Systems Consulting   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Adhesion prevention; Adhesions; Ferric hyaluronate; Fertility; Intergel solution; lactated Ringer's solution

Indexed keywords

FERRIC HYALURONATE GEL; HYALURONIC ACID; INTER GEL; PLACEBO; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; GYNECOLOGIC SURGERY; HUMAN; HUMAN TISSUE; LAPAROSCOPY; MAJOR CLINICAL STUDY; PERITONEAL CAVITY; PERITONEUM ADHESION; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SURGEON;

ADHESIONS; ADOLESCENT; ADULT; ENDOMETRIOSIS; EUROPE; FEMALE; GYNECOLOGIC SURGICAL PROCEDURES; HUMANS; HYALURONIC ACID; ISOTONIC SOLUTIONS; LAPAROSCOPY; MIDDLE AGED; OBSERVER VARIATION; OVARIAN CYSTS; PLACEBOS; POSTOPERATIVE COMPLICATIONS; REOPERATION; SAFETY; SINGLE-BLIND METHOD; UNITED STATES;

EID: 0034882612     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(01)01954-9     Document Type: Article

References (33)

1. The role of laparoscopy in chronic pelvic pain; promise and pitfalls
2. Laparoscopy in 100 women with chronic pelvic pain
3. Adhesion-related small-bowel obstruction after gynecologic operations
4. The gynecologic contribution to intestinal obstruction in females
5. Reduction of de novo postsurgical adhesions by intraoperative precoating with Sepracoat (HAL-C) solution; a prospective, randomized, blinded, placebo-controlled multicenter study
6. Complications of intraperitoneal dextran application for prevention of adhesions
7. Effect of intraperitoneal instillation of 32% dextran 70 on postoperative adhesion formation after tubal surgery
8. Failure of intraperitoneal adjuncts to improve the outcome of pelvic operations in young women
9. The source and possible significance of hyaluronan in the peritoneal cavity
10. Reduction of adhesion formation by postoperative administration of ionically crosslinked hyaluronic acid
11. Reduction of adhesion formation with hyaluronic acid following peritoneal surgery in rabbits
12. Clinical evaluation of 0.5% ferric hyluronate adhesion prevention gel for the reduction of adhesion following peritoneal cavity surgery; open-label pilot study
13. The American Fertility Society classifications of adnexal adhesions, distal tubal occlusion, tubal occlusion secondary to tubal ligation, tubal pregnancies, Mullerian anomalies and intrauterine adhesions
14. Reduction of postoperative pelvic adhesions with intra-peritoneal 32% dextran 70; a prospective, randomized clinical trial
15. High-molecular weight dextran in human infertility surgery
16. Use of instillates to prevent intraperitoneal adhesions; crystalloid and dextran
17. Prevention of pelvic adhesion formation by different modalities of treatment
18. Evaluation of adhesion formation after laparoscopic treatment of polycystic ovarian disease
19. Adhesion formation and reformation after laparoscopic removal of ovarian endometriomas
20. Adhesion formation and reproductive outcome after myomectomy and second-look laparoscopy
21. Laparoscopically instilled fluid; the rate of absorption and the effects on patient discomfort and fluid balance
22. Effect of hyaluronic acid on postoperative intraperitoneal adhesion formation and reformation in the rat model
23. Efficacy of adhesion barriers; resorbable hydrogel, oxidized regenerated cellulose and hyaluronic acid
24. Hyaluronic acid for preventing experimental postoperative intraperitoneal adhesions