Reduction of de novo postsurgical adhesions by intraoperative precoating with Sepracoat* (HAL-C) solution: A prospective, randomized, blinded, placebo-controlled multicenter study

Fertility and Sterility

Volumn 69, Issue 6, 1998, Pages 1067-1074

  Diamond, Michael P ^a,b   Bachus, Kevin ^c   Bieber, Eric ^d   Bradshaw, Karen ^e   Falcone, Tommaso ^f,u   Frishman, Gary ^g   Grunert, George ⁱ   Hansen, Keith ^j   Hemmings, Robert ^f,k   Lobo, Rogerio ^l,w   Mok, Andrew ^m   Radwanska, Ewa ⁿ   Schlaff, William ^o   Silverberg, Kaylen ^p,s   Steinkampf, Michael ^q   Vaughn, Thomas C ^r   Witz, Craig ^s   Smith, Ellen ^t   Gehlbach, Daniel ^h,v  

^a WAYNE STATE UNIVERSITY   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f ROYAL VICTORIA HOSPITAL   (Canada)

^g WOMEN AND INFANTS HOSPITAL   (United States)

^h BROOKE ARMY MEDICAL CENTER   (United States)

ⁱ Women's Hospital of Texas   (United States)

^j MEDICAL COLLEGE OF GEORGIA   (United States)

^k Lasalle General Hospital   (Canada)

^l UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^m MONTREAL GENERAL HOSPITAL   (Canada)

ⁿ RUSH UNIVERSITY MEDICAL CENTER   (United States)

^o UNIVERSITY OF COLORADO   (United States)

^p UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^q UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^r Seton Medical Center Austin   (United States)

^s UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^t GENZYME CORPORATION   (United States)

^u LERNER RESEARCH INSTITUTE   (United States)

^v UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^w New York Presbyterian Hospital Columbia University Medical Center   (United States)

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Author keywords

Adhesion formation; Adhesions; De novo adhesions; Gynecologic surgery; HAL C; Indirect surgical trauma; Postoperative adhesions; Sepracoat

Indexed keywords

HYALURONIC ACID;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LAPAROTOMY; MAJOR CLINICAL STUDY; MULTICENTER STUDY; PERITONEUM ADHESION; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SECOND LOOK SURGERY; TREATMENT OUTCOME;

ADHESIONS; ADMINISTRATION, TOPICAL; ADULT; DOUBLE-BLIND METHOD; FEMALE; GENITAL DISEASES, FEMALE; HUMANS; HYALURONIC ACID; INCIDENCE; INTRAOPERATIVE CARE; LAPAROTOMY; PELVIS; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 0032101714     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(98)00057-0     Document Type: Article

References (15)

1. 1. Diamond MP, Decherney AH. Pathogenesis of adhesion formation/ reformation: application to reproductive pelvic surgery. Microsurgery 1987;8:103-7.
2. 2. Menzies D. Postoperative adhesions: their treatment and relevance in clinical practice. Ann R Coll Surg Engl 1993;75:147-53.
3. 3. Diamond MP. Adhesion prevention. In: Gershenson DM, DeCherney AH, Curry SL, editors. Operative gynecology. Philadelphia: WB Saunders Company, 1993:147-58.
4. 4. Ray NF, Larsen JW, Stillman RJ. Economic impact of hospitalizations for lower abdominal adhesiolysis in the United States in 1988. Surg Gynecol Obstet 1993;176:271-6.
5. 5. Becker JM, Dayton MT, Fazio VW, Beck DE, Stryker SJ, Wexner SD, et al. Prevention of postoperative adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized double-blind multicenter study. J Am Coll Surg 1996;183:297-306.
6. 6. Diamond MP, Nezhat F. Adhesions after resection of ovarian endometriomas [letter]. Fertil Steril 1993;59:934.
7. 7. Data on file. Genzyme Corporation, Cambridge, Massachusetts.
8. 8. Burns JW, Skinner K, Colt J, Sheidlin A, Bronson R, Yacobi Y, et al. Prevention of tissue injury and postsurgical adhesions by precoating tissues with hyaluronic acid solutions. J Surg Res 1995;59:644-52.
9. 9. Adhesion Scoring Group. Improvement of intraobserver reproducibility of adhesion scoring systems. Fertil Steril 1994;62:984-8.
10. 10. Diamond MP, Daniell JF, Feste J, Surrey MW, McLaughlin DS, Friedman S, et al. Adhesion reformation and de novo adhesion formation after reproductive pelvic surgery. Fertil Steril 1987;47:864-6.
11. 11. Diamond MP, Daniell JF, Johns DA, Hill GA, Reich H, Martin DC, et al. Postoperative adhesion development after operative laparoscopy: evaluation at early second-look procedures. Fertil Steril 1991;65: 700-4.
12. 12. Urman B, Gomel V. Effect of hyaluronic acid on postoperative intraperitoneal adhesion formation in the rat model. Fertil Steril 1991;56: 563-7.
13. 13. Urman B, Gomel V. Effect of hyaluronic acid on postoperative intraperitoneal adhesion formation and reformation in the rat model. Fertil Steril 1991;56:568-70.
14. 14. Diamond MP, Seprafilm Adhesion Study Group. Reduction of adhesions after uterine myomectomy by Seprafilm Membrane (HAL-F), a double-blinded, prospective, randomized multicenter clinical study. Fertil Steril 1996;66:904-10.
15. 15. Franklin R, Ovarian Adhesion Study Group. Reduction of ovarian adhesions by the use of Interceed. Obstet Gynecol 1995;86:335-40.