Epithelial expression of caveolin-2, but not caveolin-1, is enhanced in the inflamed mucosa of patients with ulcerative colitis

Inflammatory Bowel Diseases

Volumn 7, Issue 3, 2001, Pages 210-214

  Andoh, Akira ^a   Saotome, Takao ^a   Sato, Haruhisa ^b   Tsujikawa, Tomoyuki ^a   Araki, Yoshio ^a   Fujiyama, Yoshihide ^a   Bamba, Tadao ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b RAKUWAKAI OTOWA HOSPITAL   (Japan)

Author keywords

Cytokine; Glycosylphosphatidylinositol (GPI) anchor; IBD

Indexed keywords

CAVEOLIN 1; CAVEOLIN 2; CAVEOLIN 3;

ARTICLE; CELL MEMBRANE; CLINICAL ARTICLE; CLINICAL FEATURE; COLON MUCOSA; CONTROLLED STUDY; CROHN DISEASE; DISEASE ACTIVITY; DISEASE ASSOCIATION; ENDOSCOPY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE EPITHELIUM CELL; INTESTINE MUSCLE; ISCHEMIC COLITIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECTUM MUCOSA; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; ULCERATIVE COLITIS;

EID: 0034882240     PISSN: 10780998     EISSN: None     Source Type: Journal    
DOI: 10.1097/00054725-200108000-00005     Document Type: Article

References (22)

1. Alteration of gene expression by intestinal epithelial cells preceding colitis in interleukin-2-deficient mice
2. Differential expression of interleukin-1 receptor antagonist isoforms in human intestinal epithelial cells
3. CD 95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells. A possible role in ulcerative colitis
4. Increased expression of decay-accelerating factor (CD55) in the inflamed mucosa of patients with ulcerative colitis
5. Enhanced expression of decay accelerating factor and CD59/homologous restriction factor 20 on the colonic epithelium of ulcerative colitis
6. Interleukin 4 acts as an inducer of decay-accelerating factor gene expression in human intestinal epithelial cells
7. Tumour necrosis factor-alpha up-regulates decay-accelerating factor gene expression in human intestinal epithelial cells
8. VIP-21/caveolin, glycosphingolipid clusters and the sorting of glycosylphosphati-dylinositol-anchored proteins in epithelial cells
9. Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae
10. Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
11. Signal transduction through decay-accelerating factor. Interaction of glycosylphosphatidylinositol anchor and protein tyrosine kinase p56lck and p59fyn 1
12. Activation of T cells via CD55: Recruitment of early components of the CD3-TCR pathway is required for IL-2 secretion
13. Interaction of receptor tyrosine kinase, EGF-R, with caveolins
14. Molecular cloning of caveolin-3, a novel member of the caveolin gene family expressed predominantly in muscle
15. The membrane-spanning domains of caveolin-1 and -2 mediate the formation of caveolin hetero-oligomers
16. Cell-type and tissue-specific expression of caveolin-2. Caveolin-1 and caveolin-2 co-localized and form a stable hetero-oligometric complex in vivo
17. Caveolin-1 and -2 expression is differentially regulated in cultured keratinocytes and within the regenerating epidermis of cutaneous wounds
18. Characterization of caveolins from cartilage: Expression of caveolin-1, -2 and -3 in chondrocytes and in alginate cell culture of the rat tibia
19. Angiogenesis activators and inhibitors differentially regulate caveolin-1 expression and caveolae formation in vascular endothelial cells
20. Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: Caveolin-2 is up-regulated in response to cell injury
21. Up-regulation of caveolae and caveolar constituents in multidrug-resistant cancer cells
22. Caveolin is present in intestinal cells: Role in cholesterol trafficking