Changes in xylosyltransferase activity and in proteoglycan deposition in bleomycin-induced lung injury in rat

European Respiratory Journal

Volumn 18, Issue 2, 2001, Pages 347-356

  Koslowski, R ^a   Pfeil, U ^a   Fehrenbach, H ^a   Kasper, M ^a   Skutelsky, E ^a   Wenzel, K W ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Lung fibrosis; Myofibroblast; Proteoglycans; Xylosyltransferase

Indexed keywords

ALPHA ACTIN; BIGLYCAN; BLEOMYCIN; DECORIN; PROTEOGLYCAN; TRANSFERASE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE XYLOSYLTRANSFERASE; VERSICAN;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CELL ISOLATION; CONCENTRATION RESPONSE; ENZYME ACTIVITY; ENZYME SUBSTRATE; FEMALE; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS MACROPHAGE; LUNG DEPOSIT; LUNG FIBROBLAST; LUNG FIBROSIS; LUNG INJURY; LUNG PARENCHYMA; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; BIOPSY; BLEOMYCIN; FEMALE; FIBROBLASTS; GLYCOSYLATION; IMMUNOENZYME TECHNIQUES; LUNG DISEASES; PENTOSYLTRANSFERASES; PROTEOGLYCANS; RATS; RATS, WISTAR;

EID: 0034882208     PISSN: 09031936     EISSN: None     Source Type: Journal    
DOI: 10.1183/09031936.01.00085601     Document Type: Article

References (51)

1. Remodeling of the lung in bleomycin-induced pulmonary fibrosis in the rat
2. Immunohistochemical evidence for loss of ICAM-1 adhesion molecule by alveolar epithelial cells in pulmonary fibrosis
3. Loss of immunoreactivity for RTI40, a type I cell-specific protein in the alveolar epithelium of rat lung with bleomycin-induced fibrosis
4. Early changes in lung tissue hyaluronan (hyaluronic acid) and hyaluronidase in bleomycin-induced alveolitis in hamsters
5. Alveolar accumulation of fibronectin and hyaluronan precedes bleomycin-induced pulmonary fibrosis in the rat
6. Regulation of alveolar macrophage transforming growth factor-β secretion by corticosteroids in bleomycin-induced pulmonary inflammation in the rat
7. Increased type I procollagen mRNA transcripts in the lungs of mice during the development of bleomycin-induced fibrosis
8. Myofibroblasts and their role in lung collagen gene expression during pulmonary fibrosis
9. 2(I) collagen gene expression in pulmonary fibrosis induced by endotracheal bleomycin injection
10. Lung fibroblast α-smooth muscle actin expression and contractile phenotype in bleomycin-induced pulmonary fibrosis
11. Antifibrotic effect of decorin in a bleomycin hamster model of lung fibrosis
12. Proteinases and proteinase inhibitors during the development of pulmonary fibrosis in rat
13. Proteoglycans: Structure and function
14. Proteoglycan involvement during development of lesional pulmonary edema
15. Involvement of lung interstitial proteoglycans in development of hydraulic- and elastase-induced edema
16. Effects of heparin and other glycosaminoglycans on elastin production by cultured neonatal rat lung fibroblasts
17. Proteoglycan deposition in pulmonary fibrosis
18. Fetal lung fibroblasts selectively down-regulate proteoglycan synthesis in response to elevated oxygen
19. Pulmonary pathology of adult respiratory distress syndrome
20. Proteoglycans in granulomatous lung diseases
21. Bronchiolitis obliterans and usual interstitial pneumonia: A comparative clinicopathological study
22. Hyaluronan and type III procollagen peptide concentrations in bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis
23. Accumulation of hyaluronic acid in the alveolar interstitial tissue in bleomycin-induced alveolitis
24. Hyaluronan (hyaluronic acid) in bronchoalveolar lavage fluid during the development of bleomycin-induced alveolitis in the rat
25. Immunocytochemical localization of proteoglycans within normal elastin fibres
26. Induction of emphysematous lesions in rat lung by β-D-xyloside, an inhibitor of proteoglycan synthesis
27. Interaction of a 59 kDa connective tissue matrix protein with collagen I and collagen II
28. Role of decorin on in vitro fibrillogenesis of type I collagen
29. Negative regulation of transforming growth factor-β by the proteoglycan decorin
30. Extracellular matrix/growth factor interactions
31. Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor β
32. Adenovirus-mediated decorin gene transfer prevents TGF-β-induced inhibition of lung morphogenesis
33. Altered expression of small proteoglycans, collagen, and transforming growth factor-β1 in developing bleomycin-induced pulmonary fibrosis in rats
34. Purification and some properties of UDP-xylosyltransferase of rat ear cartilage
35. Localization of surfactant protein A (SP-A) in alveolar macrophage subpopulations of normal and fibrotic rat lung
36. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
37. Hyaluronate binding properties of versican
38. Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins
39. Purification and partial characterization of small proteoglycans I and II, bone sialoproteins I and II, and osteonectin from the mineral compartement of developing human bone
40. Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (Decorin) and several nonconnective tissue proteins in a variety of species
41. Cationic colloidal gold - A new probe for the detection of anionic cell surface sites by electron microscopy
42. Distribution of proteoglycans in rat renal tubular epithelium
43. Immunohistochemical distribution of E-cadherin in normal and injured lung tissue of the rat
44. Differential regulation of extracellular matrix proteoglycan (PG) gene expression
45. PDGF-induced glycosaminoglycan synthesis is mediated via phosphatidylinositol 3-kinase
46. Structural Organization of the Pulmonary interstitium
47. Lung myofibroblasts
48. Rat alveolar myofibroblasts acquire α-smooth muscle actin expression during bleomycin-induced pulmonary fibrosis
49. The myofibroblast as an inflammatory cell in pulmonary fibrosis
50. Temporal and spatial expression of biglycan in chronic oxygen-induced lung injury
51. Changes in decorin expression with hyperoxic injury to developing rat lung