Predictable individual differences in the initiation of cocaine self-administration by rats under extended-access conditions are dose-dependent

Psychopharmacology

Volumn 157, Issue 1, 2001, Pages 31-39

  Mantsch, J R ^a   Ho, A ^a   Schlussman, S D ^a   Kreek, M J ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Acquisition; Cocaine; Corticosterone; Extended access; Individual differences; Novelty; Prolactin; Rat; Self administration

Indexed keywords

COCAINE; CORTICOSTERONE; PROLACTIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CORTICOSTERONE BLOOD LEVEL; DOSE RESPONSE; DRUG MEGADOSE; DRUG SELF ADMINISTRATION; INDIVIDUALITY; LOCOMOTION; MALE; NEUROENDOCRINE DISEASE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; RAT; REINFORCEMENT;

ANIMALS; COCAINE; CORTICOSTERONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXPLORATORY BEHAVIOR; MALE; PROLACTIN; RATS; RATS, SPRAGUE-DAWLEY; REGRESSION ANALYSIS; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION;

EID: 0034879420     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002130100744     Document Type: Article

References (35)

1. Transition from moderate to excessive drug intake: Change in hedonic set point
2. Dopamine: A prolactin inhibiting hormone
3. Toxicity associated with long-term intravenous heroin and cocaine self-administration in the rat
4. Acquisition of IV amphetamine and cocaine self-administration in rats as a function of dose
5. A concurrently available non-drug reinforcer prevents the acquisition or decreases the maintenance of cocaine-reinforced behavior
6. Nijmegen high and low responders to novelty: A new tool in the search after the neurobiology of drug abuse liability
7. Differences in vulnerability and susceptibility to dexamphetamine in Nijmegen high and low responders to novelty: A dose-effect analysis of spatio-temporal programming of behaviour
8. Experimental approach to individual vulnerability to psychostimulant addiction
9. Self-administration of psychoactive substances by the monkey: A measure of psychological dependence
10. The effects of dose and access restrictions on the periodicity of cocaine self-administration in the rat
11. Abstinence symptomology and psychiatric diagnosis in cocaine abusers
12. Role of corticosterone in intravenous cocaine self-administration
13. Sucrose intake predicts rate of acquisition of cocaine self-administration
14. Individual differences in locomotor activity and sensitization
15. Individual differences in basal and cocaine-stimulated extracellular dopamine in the nucleus accumbens using quantitative microdialysis
16. 2 receptors
17. Animals · predisposed to develop amphetamine self-administration show higher susceptibility to develop contextual conditioning of both amphetamine-induced hyperlocomotion and sensitization
18. Self-administration of psychomotor stimulant drugs: The effects of unlimited access
19. Corticosterone facilitates the acquisition of cocaine self-administration in rats: Opposite effects of the type II glucocorticoid receptor antagonist dexamethasone
20. Effects of cocaine self-administration on plasma corticosterone and prolactin in rats
21. Dose-related effects of extended drug access on cocaine self-administration, extinction, and reinstatement in rats
22. Postcocaine anhedonia - An animal model of cocaine withdrawal
23. Withdrawal from IV cocaine "binges" in rats: Ultrasonic distress calls and startle
24. Serotonin dysfunction in the nucleus accumbens of rats during withdrawal after unlimited access to intravenous cocaine
25. Factors that predict individual vulnerability to amphetamine self-administration
26. Corticosterone levels determine individual vulnerability to amphetamine self-administration
27. Vertical shifts in self-administration dose-response functions predict a drug-vulnerable phenotype predisposed to addiction
28. Divergent prolactin and pituitary-adrenal activity in rats selectively bred for different dopamine responsiveness
29. Higher and longer stress-induced increases in dopamine concentrations in the nucleus accumbens of animals predisposed to amphetamine self-administration. A microdialysis study
30. Changing patterns of cocaine use: Longitudinal observations, consequences, and treatment
31. Cocaine self-administration "binges": Transition from behavioral and autonomic regulation toward homeostatic dysregulation in rats
32. Time course of the development of behavioral sensitization and dopamine receptor upregulation during binge cocaine administration
33. Intravenous self-administration of drugs in rats
34. Basal extracellular dopamine levels in the nucleus accumbens during cocaine withdrawal after unlimited-access self-administration