Remyelination of the adult demyelinated mouse brain by grafted oligodendrocyte progenitors and the effect of B-104 cografts

Neurochemical Research

Volumn 26, Issue 6, 2001, Pages 673-682

  Espinosa De Los Monteros, A ^a   Baba, H ^b   Zhao, P M ^a   Pan, T ^a   Chang, R ^a   De Vellis, J ^a   Ikenaka, K ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL INSTITUTE FOR PHYSIOLOGICAL SCIENCES   (Japan)

Author keywords

Cell transplant; Neurotrophic factors; Oligodendrocytes; Proteolipid protein; Remyelination

Indexed keywords

MYELIN BASIC PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROLLED STUDY; DEMYELINATION; GENE OVEREXPRESSION; IMMUNOFLUORESCENCE; MOUSE; NEUROFILAMENT; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; REMYELINIZATION; STEM CELL; TRANSGENIC MOUSE;

ANIMALS; BRAIN DISEASES; CELL LINE; CELL MOVEMENT; CELL SURVIVAL; DEMYELINATING DISEASES; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MYELIN BASIC PROTEINS; MYELIN SHEATH; OLIGODENDROGLIA; RNA, MESSENGER; STEM CELL TRANSPLANTATION; STEM CELLS; TRANSFERRIN;

EID: 0034879097     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010943505013     Document Type: Article

References (26)

1. A proteolipid protein gene family: Expression in sharks and rays and possible evolution from an ancestral gene encoding a pore-forming polypeptide
2. Chemical deacylation reduces the adhesive properties of proteoliped protein and leads to decompaction of the myelin sheath
3. Neuropathology and genetics of Pelizaeus-Merzbacher disease
4. Proteolipid protein gene duplications causing Pelizaeus-Merzbacher disease: Molecular mechanism and phenotypic manifestations
5. Inherited disorders of myelination of the central nervous system
6. Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene
7. Myelination and remyelination in the central nervous system by transplanted oligodendrocytes using the shiverer model. Discussion on the remyelinating cell population in adult mammals
8. The use of transplanted glial cells to reconstruct glial environments in the CNS
9. Transplantation of cultured premyelinating oligodendrocytes into normal and myelin-deficient rat brain
10. O2A progenitor cells transplanted into the neonatal rat brain develop into oligodendrocytes but not astrocytes
11. Transplantation of CG4 oligodendrocyte progenitor cells in the myelin-deficient rat brain results in myelination of axons and enhanced oligodendroglial markers
12. Remyelination of the adult demyelination mouse brain by grafted oligodendrocyte progenitors
13. CG-4, a new bipotential glial cell line from rat brain is capable of differentiating in vitro into either mature oligodendrocytes or type-2 astrocytes
14. The proximal promoter region is sufficient to regulate the tissue specific expression of UDP-galactose; ceramide galactosyl-transferase gene
15. An in vitro injury model for oligodendrocyte
16. Transferrin is an essential factor for myelination
17. Transplanted CG4 cells (an oligondendrocyte progenitor cell line) survive, migrate and contribute to repair of areas of demyelination in the x-irradiated and damaged spinal cord but not in normal spinal cord
18. Inflammation promotes survival and migration of the CG4 oligodendrocyte progenitors transplanted in the spinal cord of both inflammatory and demyelinated EAE rats
19. Transplantation of an oligodendrocyte cell line leading to extensive myelination
20. Enhanced proliferation and directed migration of oligodendroglial progenitors cografted with growth factor-secreting cell
21. Myelin basic protein and transferrin characterize different subpopulations of oligodendrocytes in rat primary glial cultures
22. Developmental expression of glial specific mRNAs in primary cultures of rat brain visualized by in situ hybridization
23. A procedure for long-term culture of oligodendrocytes
24. Control of oligodendrocyte number in the developing rat optic nerve
25. Platelet-derived growth factor receptor is expressed by cells in the early oligodendrocyte lineage
26. Evidence for neuronal regulation of oligodendrocyte development: Cellular localization of platelet-derived growth factor α receptor and A-chain mRNA during cerebral cortex development in the rat