The effects of hypothyroidism on 5-HT1A and 5-HT2A receptors and the serotonin transporter protein in the rat brain

Neuroscience and Behavioral Physiology

Volumn 31, Issue 4, 2001, Pages 445-449

  Kulikov, A V ^a   Jeanningro, R ^b  

^a INSTITUTE OF CYTOLOGY AND GENETICS   (Russian Federation)

^b INSERM   (France)

Author keywords

5 HT1A receptors; 5 HT2A receptors; Brain; Hypothyroidism; Serotonin transporter; Thyroxine

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CITALOPRAM; IODINE; KETANSERIN; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN TRANSPORTER; THYROID HORMONE; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; COMPARATIVE STUDY; CONTROLLED STUDY; DIET; DRUG EFFECT; DRUG RECEPTOR BINDING; FRONTAL CORTEX; HIPPOCAMPUS; HORMONE DETERMINATION; HYPOTHYROIDISM; MALE; MESENCEPHALON; NONHUMAN; RAT; RAT STRAIN; SEROTONINERGIC SYSTEM; THYROIDECTOMY;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BRAIN CHEMISTRY; CARRIER PROTEINS; CITALOPRAM; EXCITATORY POSTSYNAPTIC POTENTIALS; HIPPOCAMPUS; HYPOTHYROIDISM; INDICATORS AND REAGENTS; KETANSERIN; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MESENCEPHALON; NERVE TISSUE PROTEINS; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; SEROTONIN ANTAGONISTS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; THYROIDECTOMY; THYROXINE;

EID: 0034878940     PISSN: 00970549     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010401015064     Document Type: Article

References (33)

1. 3H]citalopram as markers of the human brain 5-HT uptake sites: A comparison study
2. Norepinephrine and serotonin transporters. Molecular targets of antidepressant drugs
3. Current advances and trends in the treatment of depression
4. 2A receptor function. Hypothesis for a faster antidepressant action
5. A rapid and sensitive method for the quantitation of microgram quantities of protein - Dye binding
6. Neuroendocrine evidence for an association between hypothyroidism, reduced central 5-HT activity and depression
7. Thyroxine replacement increases central 5-hydroxytryptamine activity and reduces depressive symptoms in hypothyroidism
8. Neuroendocrine measures of 5-HT receptor function in depression
9. 3H]imipramine
10. Cerebral versus peripheral regulation and utilization of thyroid hormones
11. Thyroid hormones and neurotransmitters
12. Functional characteristics of heterologously expressed 5-HT receptors
13. Depression as a spreading neuronal adjustment disorder
14. Indoleamines: The role of serotonin in clinical disorders
15. 1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis
16. 2 sites in cortex and amygdala
17. The thyroid and depression
18. The role of thyroid hormones in depression
19. 2A receptor, and 5-HT transporter binding in grouped and isolated Roman RHA and RLA rats. Relationships with behaviour in two models of anxiety
20. 2) and adrenergic receptors in rat cerebral cortex following novel classical antidepressant treatment
21. 2 receptor binding sites
22. The serotonin hypothesis of major depression
23. The effects of thyroid state of beta-adrenergic and serotonergic receptors in rat brain
24. I-triiodothyronine: Is this peripheral hormone a central neurotransmitter
25. Central serotonin 1A receptors: Distributions of endogenous mRNA, receptor protein and binding sites by in situ hybridization histochemistry, radioimmunohistochemistry and autoradiographic mapping in the rat brain
26. LIGAND: A versatile computerized approach for the characterization of ligand binding systems
27. Depression and endocrine disorders. Focus on the thyroid and adrenal system
28. Reversible morphological alterations of cortical neurons in juvenile and adult hypothyroidism in the rat
29. 1A receptors and 5-HT uptake sites in rat brain: An autoradiographic analysis
30. Decreased central serotonin function in hypothyroidism
31. 1 receptor subtypes in the brain of control and 5,7-DHT-treated rats
32. 2A receptors are expressed on pyramidal cells and interneurons in the rat cortex
33. 5-Hydroxytryptamine receptors