Preventing lithium intoxication: Guide for physicians

Canadian Family Physician

Volumn 47, Issue AUG., 2001, Pages 1595-1600

  Delva, Nicholas J ^a   Hawken, Emily R ^b  

^a QUEEN S UNIVERSITY   (Canada)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

LITHIUM;

ADULT; AWARENESS; CARDIOTOXICITY; CASE REPORT; COMORBIDITY; DEPRESSION; DIARRHEA; DOSE CALCULATION; DRUG INTOXICATION; DRUG MONITORING; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; KIDNEY FAILURE; NEPHROTOXICITY; NEUROTOXICITY; REVIEW; RISK FACTOR; SYNCOPE; VOMITING;

AGED; ANTIMANIC AGENTS; BIPOLAR DISORDER; DRUG MONITORING; FEMALE; HUMANS; LITHIUM CARBONATE; OVERDOSE; PRACTICE GUIDELINES; RISK FACTORS;

EID: 0034877367     PISSN: 0008350X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (50)

1. Jefferson JW. Lithium: the present and the future. J Clin Psychiatry 1995;56:41-8.
2. Adityanjee. The syndrome of irreversible lithium-effectuated neurotoxicity. In: Birch NJ, editor. Lithium: inorganic pharmacology and psychiatric use. Oxford, Engl: IRL Press Ltd; 1988. p. 65-6.
3. Verdoux H, Bourgeois ML. A case of lithium neurotoxicity with irreversible cerebellar syndrome. J Nerv Ment Dis 1990;178:761-2.
4. Terao T, Abe H, Abe K. Irreversible sinus node dysfunction induced by resumption of lithium therapy. Acta Psychiatr Scand 1996;93:407-8.
5. Hetmar O. The impact of long-term lithium treatment on renal function and structure. Acta Psychiatr Scand Suppl 1988;345:85-9.
6. Amdisen A, Gottfries CG, Jacobsson L, Winblad B. Grave lithium intoxication with fatal outcome. Acta Psychiatr Scand Suppl 1974;255:25-33.
7. Bell AJ, Cole A, Eccleston D, Ferrier IN. Lithium neurotoxicity at normal therapeutic levels. Br J Psychiatry 1993;162:689-92.
8. Brown WT. Side effects of lithium therapy and their treatment. Can Psychiatr Assoc J 1976;21:13-21.
9. Groleau G. Lithium toxicity. Emerg Med Clin North Am 1994;12:511-31.
10. Okusa MD, Crystal LJT. Clinical manifestations and management of acute lithium intoxication. Am J Med 1994;97:383-9.
11. Timmer RT, Sands JM. Lithium intoxication. J Am Soc Nephrol 1999;10:666-74.
12. Van der Velde CD. Toxicity of lithium carbonate in elderly patients. Am J Psychiatry 1971;127:1075-7.
13. Roose SP, Bone S, Haidorfer C, Dunner DL, Fieve RR. Lithium treatment in older patients. Am J Psychiatry 1979;136:843-4.
14. Smith RE, Helms PM. Adverse effects of lithium therapy in the acutely ill elderly patient. J Clin Psychiatry 1982;43:94-9.
15. Kelwala S, Pomara N, Stanley M, Sitaram N, Gershon S. Lithium-induced accentuation of extrapyramidal symptoms in individuals with Alzheimer's disease. J Clin Psychiatry 1984;45:342-4.
16. Gordon M, Preiksaitis HG. Drugs and the aging brain. Geriatrics 1988;43:69-78.
17. Brody H. The aging brain. Acta Neurol Scand Suppl 1992;137:40-4.
18. Vaccari A, Saba PL, Mocci I, Ruiu S. Is increased neurotoxicity a burden of the ageing brain? In: Freund HJ, Sabel BA, White OW, editors. Brain plasticity. Philadelphia, Pa: Lippincott-Raven; 1997. p. 221-34.
19. Ramchandani D, Schindler BA. The lithium toxic patient in the medical hospital: diagnostic and management dilemmas. Int J Psychiatry Med 1993;23:55-62.
20. Roffe C. Aging of the heart. Br J Biomed Sci 1998;55:136-48.
21. Norman TR, Walker RG, Burrows GD. Renal function related changes in lithium kinetics. Clin Pharmacokinet 1984:9:349-53.
22. Johnson GFS, Hunt GE, Duggin GG, Horvath JS, Tiller DJ. Renal function and lithium treatment: initial and follow-up tests in manic-depressive patients. J Affect Disord 1984;6:249-63.
23. Hetmar O, Jull Povlsen U, Ladefoged J, Bolwig TG. Lithium: long-term effects on the kidney; a prospective follow-up study ten years after kidney biopsy. Br J Psychiatry 1991;158:53-8.
24. Wei JY. Age and the cardiovascular system. N Engl J Med 1992;327:1735-9.
25. Leventhal EA. Biology of aging. In: Sadavoy J, Lazarus LW, Jarvik LF, Grossberg GT, editors. Comprehensive review of geriatric psychiatry-II. 2nd ed. Washington, DC: American Psychiatric Press Inc; 1996. p. 81-112.
26. Rosenqvist M, Bergfeldt L, Aili H, Mathé AA. Sinus node dysfunction during long-term lithium treatment. Br Heart J 1993;70:371-5.
27. Lippmann S, Wagemaker H, Tucker D. A practical approach to management of lithium concurrent with hyponatremia, diuretic therapy and/or chronic renal failure. J Clin Psychiatry 1981;42:304-6.
28. Thomsen K, Schou M. Avoidance of lithium intoxication: advice based on knowledge about renal lithium clearance under various circumstances. Pharmacopsychiatry 1999;32:83-6.
29. Fliser D, Franek E, Joest M, Block S, Mutschler E, Ritz E. Renal function in the elderly: impact of hypertension and cardiac function. Kidney Int 1997;51:1196-204.
30. Numata T, Abe H, Terao T, Nakashima Y. Possible involvement of hypothyroidism as a cause of lithium-induced sinus node dysfunction. Pace 1999;22:954-7.
31. Tielens ET, Pillay M, Storm C, Berghout A. Cardiac function at rest in hypothyroidism evaluated by equilibrium radionuclide angiography. Clin Endocrinol 1999;50:497-502.
32. Lôo H, Gay C, Galinowski A. Concomitant physical illness. In: Johnson FN, editor. Depression and mania: modern lithium therapy. Oxford, Engl: IRL Press Limited; 1987. p. 146-50.
33. Jus A, Villeneuve A, Gautier J, Pires A, Côté JM, Jus K, et al. Influence of lithium carbonate on patients with temporal lobe epilepsy. Can Psychiatr Assoc J 1973;18:77-8.
34. Himmelhoch JM, Neil JF, May SJ, Fuchs CZ, Licate SM. Age, dementia, dyskinesias and lithium response. Am J Psychiatry 1980;137:941-5.
35. Prakash R, Kelwala S, Ban TA. Neurotoxicity in patients with schizophrenia during lithium therapy. Compr Psychiatry 1982;23:271-3.
36. Mostowitz AS, Altshuler L. Increased sensitivity to lithium-induced neurotoxicity after stroke: a case report. J Clin Psychopharmacol 1991;11:272-3.
37. Finley PR, Warner MD, Peabody CA. Clinical relevance of drug interactions with lithium. Clin Pharmacokinet 1995;29:172-91.
38. Beermann B, Edhag O. Depressive effects of carbamazepine on idioventricular rhythm in man. BMJ 1978;2:171-2.
39. Kennebäck G, Bergfeldt L, Vallin H, Tomson T, Edhag O. Electrophysiologic effects and clinical hazards of carbamazepine treatment for neurologic disorders in patients with abnormalities of the cardiac conduction system. Am Heart J 1991;121:1421-9.
40. Kasarskis EJ, Kuo C, Berger R, Nelson KR. Carbamazepine-induced cardiac dysfunction: characterization of two distinct clinical syndromes. Arch Intern Med 1992;152:186-91.
41. Steckler TL. Lithium- and carbamazepine-associated sinus node dysfunction: nine-year experience in a psychiatric hospital. J Clin Psychopharmacol 1994;14:336-9.
42. Delgado-Escueta AV, Janz D. Consensus guidelines: preconception counseling, management, and care of the pregnant woman with epilepsy. Neurology 1992;42(Suppl 5):149-60.
43. Hansen HE, Amdisen A. Lithium intoxication: report of 23 cases and review of 100 cases from the literature. Q J Med 1978;186:123-44.
44. Hagman A, Arnman K, Rydén L. Syncope caused by lithium treatment: report on two cases and a prospective investigation of the prevalence of lithium-induced sinus node dysfunction. Acta Med Scand 1979;205:467-71.
45. Rodney WM, Chopivsky P, Hara JH. Lithium-induced dysrhythmias as a marker for sick sinus syndrome. J Fam Pract 1983;16:797-9.
46. Walker RG, Kincaid-Smith P. Kidneys and the fluid regulatory system. In: Johnson FN, editor. Depression and mania: modern lithium therapy. Oxford, Engl: IRL Press Limited; 1987. p. 206-13.
47. Ong ACM, Handler CE. Sinus arrest and asystole due to severe lithium intoxication. Int J Cardiol 1991;30:364-6.
48. Martin CA, Dickson LR, Kuo CS. Heart and blood vessels. In: Johnson FN, editor. Depression and mania: modern lithium therapy. Oxford, Engl: IRL Press Limited; 1987. p. 213-8.
49. Sugarman JR. Management of lithium intoxication. J Fam Pract 1984;18:237-9.
50. Gomolin IH. Coping with excessive doses. In: Johnson FN, editor. Depression and mania: modern lithium therapy. Oxford, Engl: IRL Press Limited; 1987. p. 154-8.