Apoptosis induction by sennoside laxatives in man: Escape from a protective mechanism during chronic sennoside use?

Journal of Pathology

Volumn 194, Issue 4, 2001, Pages 493-499

  Van Gorkom, Britta A P ^a   Karrenbeld, Arend ^a   Van Sluis, Tineke Der ^a   Zwart, Nynke ^a   De Vries, Elisabeth G E ^a   Kleibeuker, Jan H ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Apoptosis; bcl 2; Carcinogenesis; Colon; Laxatives; p53; Proliferation; Sennosides

Indexed keywords

PROTEIN BCL 2; PROTEIN P21; PROTEIN P53; SENNOSIDE; X PREP;

ADULT; APOPTOSIS; ARTICLE; CANCER RISK; CELL PROLIFERATION; COLON BIOPSY; COLON CARCINOGENESIS; COLON MUCOSA; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE SEVERITY; DRUG USE; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTESTINE CRYPT; LABELING INDEX; MALE; MELANOSIS; MUCOSA CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; RECTUM BIOPSY; RECTUM MUCOSA; SIGMOIDOSCOPY; TIME;

EID: 0034876684     PISSN: 00223417     EISSN: None     Source Type: Journal    
DOI: 10.1002/path.914     Document Type: Article

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