Role of genetic algorithms and artificial neural networks in predicting the phase behavior of colloidal delivery systems

Pharmaceutical Research

Volumn 18, Issue 7, 2001, Pages 1049-1055

  Agatonovic Kustrin, S ^a   Alany, R G ^b,c  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

ANNs; Cosurfactant; GNNs; Microemulsion; Molecular descriptors; Phase behavior

Indexed keywords

COSURFACTANT; HYDROCARBON; OLEIC ACID;

ACCURACY; ARTICLE; ARTIFICIAL NEURAL NETWORK; CALCULATION; CHEMICAL COMPOSITION; COLLOID; DRUG DELIVERY SYSTEM; DRUG FORMULATION; LIQUID CRYSTAL; MICROEMULSION; MOLECULAR MODEL; NERVE CELL; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; TECHNIQUE;

ALGORITHMS; CHEMISTRY, PHARMACEUTICAL; COLLOIDS; DRUG DELIVERY SYSTEMS; MODELS, GENETIC; NEURAL NETWORKS (COMPUTER); PREDICTIVE VALUE OF TESTS; SURFACE-ACTIVE AGENTS;

EID: 0034873206     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1010913017092     Document Type: Article

References (24)

1. The effect of alcohols with different structures on the formation of warm o/w microemulsions
2. 2O/n-octane/C(8)E(5)/n-octanol - Role of the alcohol in microemulsions
3. Preparing nontoxic microemulsions with alkyl monoglucosides and the role of alkanediols as cosolvents
4. Surfactant-water liquid crystal phases
5. Liquid crystals and their application
6. Microemulsions in technical processes
7. Effects of alcohols and diols on the phase behaviour of quaternary systems
8. Assessing the importance of features for multi-layer perceptrons
9. Three medical examples in neural network rule extraction
10. MLP iterative construction algorithm
11. Genetic algorithms in molecular recognition and design
12. Evolutionary optimization in quantitative structure-activity relationship: An application of genetic neural networks
13. Three-dimensional quantitative structure-activity relationship from molecular similarity matrices and genetic neural networks
14. Simulating lipophilicity of organic molecules with a back-propagation neural network
15. Physicochemical significance of topological parameters - Molecular connectivity index and information. Content 2: Correlation studies with molecular refractivity and liphylicity
16. An estimation of the atomic contribution to octanol-water partition-coefficient and molar refractivity from fundamental atomic and structural properties - Its use in computer aided drug design
17. Factors determining emulsion type-hydrophile-lipophile balance and beyond
18. The linear free-energy relationship between partition coefficient and the aqueous solubility of organic liquids
19. Effects with descriptors directly from 3D-structures using a comparative molecular-field analysis (COMFA) approach
20. Lecithin-based microemulsions. Phase behaviour and microstructure