Comprehensive kinetic analysis of influenza hemagglutinin-mediated membrane fusion: Role of sialate binding

Biophysical Journal

Volumn 81, Issue 3, 2001, Pages 1521-1535

  Mittal, Aditya ^a   Bentz, Joe ^a  

^a DREXEL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS HEMAGGLUTININ;

ARTICLE; BILAYER MEMBRANE; CHEMICAL REACTION KINETICS; CONFORMATIONAL TRANSITION; INFLUENZA VIRUS; MEMBRANE FUSION; MODEL; MOLECULAR DYNAMICS; NONHUMAN;

EID: 0034872358     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)75806-7     Document Type: Article

References (51)

1. Fusion of influenza virus with sialic acid-bearing target membranes
2. Intermediates and kinetics of membrane fusion
3. Minimal aggregate size and minimal fusion unit for the first fusion pore of influenza hemagglutinin-mediated membrane fusion
4. Membrane fusion mediated by coiled coils: A hypothesis
5. An architecture for the fusion site of influenza hemagglutinin
6. Deployment of membrane fusion protein domains during fusion
7. Dilation of the influenza hemagglutinin fusion pore revealed by the kinetics of individual fusion events
8. Structure of the influenza haemagglutinin at neutral and at fusogenic pH by electron cryo-microscopy
9. Structure of influenza haemagglutinin at the pH of membrane fusion
10. Influenza hemagglutinin is spring-loaded by a metastable native configuration
11. On the use of self-quenching fluorophores in the study of membrane fusion kinetics. The effect of slow probe redistribution
12. A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low pH induced conformation
13. The pathway of membrane fusion catalyzed by influenza hemagglutinin: Restriction of lipids, hemifusion, and lipid fusion pore formation
14. An early stage of membrane fusion mediated by the low pH conformation of influenza hemagglutinin depends upon membrane lipids
15. Membrane fusion mediated by the influenza virus hemagglutinin requires the concerted action of at least three hemagglutinin trimers
16. Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change
17. Fluorescence assays for membrane fusion
18. Fusion of influenza hemagglutinin-expressing fibroblasts with glycophorin-bearing liposomes: Role of hemagglutinin surface density
19. Role of hemagglutinin surface density in the initial stages of influenza virus fusion: Lack of evidence for cooperativity
20. Influence of lipid composition on physical properties and peg-mediated fusion of curved and uncurved modelmembrane vesicles: "Nature's own" fusogenic lipid bilayer
21. Virus-cell and cell-cell fusion
22. Fluorescence method for measuring the kinetics of fusion between biological membranes
23. A mechanism of protein-mediated fusion: Coupling between refolding of the influenza hemagglutinin and lipid rearrangements
24. Secretory and viral fusion may share mechanistic events with fusion between curved lipid bilayers
25. Delay of influenza hemagglutinin refolding into a fusion-competent conformation by receptor binding: A hypothesis
26. Protein machines and lipid assemblies: Current views of cell membrane fusion
27. Chemical characterization and surface orientation of the major glycoprotein of the human erythrocyte membrane
28. The lipid-anchored ectodomain of influenza virus hemagglutinin (GPI-HA) is capable of inducing nonenlarging fusion pores
29. Evolution of intermediates of influenza virus hemagglutinin-mediated fusion revealed by kinetic measurements of pore formation
30. The role of the cytoplasmic tail region of influenza virus hemagglutinin in formation and growth of fusion pores
31. Amino acid sequence requirements of the transmembrane and cytoplasmic domains of influenza virus hemagglutinin for viable membrane fusion
32. A point mutation in the transmembrane domain of the hemagglutinin of influenza virus stabilizes a hemifusion intermediate that can transit to fusion
33. The fusion kinetics of influenza hemagglutinin expressing cells to planar bilayer membranes is affected by HA surface density and host cell surface
34. Membrane fusion by surrogate receptor-bound influenza haemagglutinin
35. Kinetics of RBC fusion with influenza hemagglutinin-expressing cells as a function of technique
36. Single event recording shows that docking onto receptor alters the kinetics of membrane fusion mediated by influenza hemagglutinin
37. Control of biological activities of influenza virus hemagglutinin by its carbohydrate moiety
38. Glycosylation sites identified by solid-phase Edman degradation: O-linked glycosylation motifs on human glycophorin A
39. Specific single or double proline substitutions in the "spring-loaded" coiled coil region of the influenza hemagglutinin impair or abolish membrane fusion activity
40. Hemagglutinins from two influenza virus variants bind to sialic acid derivatives with millimolar dissociation constants: A 500-MHz proton nuclear magnetic resonance study
41. Influenza virus-liposomes lipid mixing is leaky and largely insensitive to the material properties of the target membrane
42. Morphological changes and fusogenic activity of influenza virus hemagglutinin
43. Coiled coils in both intracellular vesicle and viral membrane fusion
44. Influenza hemagglutinin-mediated membrane fusion: Influence of receptor binding on the lag phase preceding fusion
45. Intermediates in influenza induced membrane fusion
46. Anti-peptide antibodies detect steps in a protein conformational change: Low-pH activation of the influenza virus hemagglutinin
47. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution
48. An analytic solution to the Forster energy transfer problem in two dimensions
49. Insertion of a coiled-coil peptide from influenza virus hemagglutinin into membranes
50. Restricted movement of lipid and aqueous dyes through pores formed by influenza hemagglutinin during cell fusion